gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Apoptosis, caspase activation inhibitor

Top mentioned proteins: Bcl-xL, PrP, p53, CAN, Atm
Papers on Aven
Genetic polymorphisms associated with increased risk of developing chronic myelogenous leukemia.
Rousselot et al., Paris, France. In Oncotarget, Dec 2015
The HDAC9, AVEN, SEMA3C, IKBKB, GSTA3, RIPK1 and FGF2 genes were each represented by three SNPs, the PSM family by four SNPs and the SLC15A1 gene by six.
Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.
Danen et al., Leiden, Netherlands. In J Pathol, Jul 2015
In this study we found that expression of Aven correlates inversely with metastasis-free survival in osteosarcoma patients and is increased in metastases compared to primary tumours.
Akt regulation of Aven contributes to the sensitivity of cancer cells to chemotherapeutic agents.
Kim et al., Seoul, South Korea. In Mol Med Report, May 2015
In the present study, it was demonstrated that the protein level of the apoptosis inhibitor Aven is regulated by the Akt signaling pathway, evidenced by the observation that Aven levels were significantly increased in MCF7 constitutively active (CA)‑Akt cells and significantly inhibited following treatment with LY294002.
The stage-specific testicular germ cell apoptotic response to low-dose radiation and 2,5-hexanedione combined exposure. II: qRT-PCR array analysis reveals dose dependent adaptive alterations in the apoptotic pathway.
Boekelheide et al., Providence, United States. In Toxicol Pathol, 2014
The apoptosis PCR arrays identified significant dose-dependent treatment effects on several genes, with downregulation of death receptor 5 (DR5), Naip2, Sphk2, Casp7, Aven, Birc3, and upregulation of Fas.
Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.
Richard et al., Montréal, Canada. In Elife, 2014
Herein, we show that Aven stimulates the mRNA translation of the mixed lineage leukemia (MLL) proto-oncogene in an arginine methylation-dependent manner.
Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites.
Gudjonsson et al., Ann Arbor, United States. In Clin Transl Med, 2014
We identified a limited set of DEGs that encode proteins interacting with PRE motifs, including TFs (GATA3, EHF, FOXM1, SOX5) and uDBPs (AVEN, RBM8A, GPAM, WISP2).
Nitric oxide donor NOC-5 increases XIAP and Aven level in Jurkat cells.
Ryazantseva et al., Tomsk, Russia. In Cell Biol Int, 2014
We have studied the X-linked apoptosis inhibitor (XIAP) and Aven protein content in NO-treated Jurkat cells.
Progesterone regulation of AVEN protects bovine oocytes from apoptosis during meiotic maturation.
Fair et al., Dublin, Ireland. In Biol Reprod, 2013
These altered IVM conditions resulted in dynamic changes in protein expression of the progesterone receptors and the cell death-regulated proteins AVEN, BCL-xL, and active caspase 3.
Effect of Bcl-x(L) overexpression on lactate metabolism in chinese hamster ovary cells producing antibody.
Lee et al., Taejŏn, South Korea. In Biotechnol Prog, 2013
Previously, overexpression of anti-apoptotic proteins, such as E1B-19K and Aven, was reported to alter lactate metabolism of CHO cells in culture.
Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy.
Spray et al., Valhalla, United States. In Eur J Neurosci, 2013
Cacng1, Nadsyn1, Kcng1, Aven, S100a4, GFAP, Vim, Hrsp12 and Grik1).
Enantioselective induction of cytotoxicity by o,p'-DDD in PC12 cells: implications of chirality in risk assessment of POPs metabolites.
Liu et al., Hangzhou, China. In Environ Sci Technol, 2013
We have documented for the first time that R-(+)-o,p'-DDD increases apoptosis by selectively disturbing the oxidative system (enzymes and molecules) and regulating the transcription of Aven, Bid, Cideb and Tp53.
MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells.
Hernandez-Vargas et al., Lyon, France. In Bmc Genomics, 2012
At least one of these targets, the anti-apoptotic protein AVEN, was able to partially revert the effect of miR-30a overexpression.
Aven is dynamically regulated during Xenopus oocyte maturation and is required for oocyte survival.
Hensey et al., Dublin, Ireland. In Cell Death Dis, 2012
We have analyzed the expression and function of the cell death and cell cycle regulator Aven in Xenopus.
Sevoflurane and isoflurane preconditioning provides neuroprotection by inhibition of apoptosis-related mRNA expression in a rat model of focal cerebral ischemia.
Ozkose et al., Ankara, Turkey. In J Neurosurg Anesthesiol, 2012
Proapoptotic genes (Tnf, Tnfrsf10b, and Tp53) downregulated and antiapoptotic genes (Aven, Bcl2, Bcl2l2, and Prok2) upregulated with sevoflurane treatment compared with the isoflurane and control groups.
Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis.
Socorro et al., Covilhã, Portugal. In Fertil Steril, 2011
The results suggest that deregulation of the expression of the apoptosis inhibitor Aven may be related to male factor infertility.
Regulation of the ATM-activator protein Aven by CRM1-dependent nuclear export.
Irusta et al., Washington, D.C., United States. In Cell Cycle, 2010
Results suggest that the regulation of Exportin-1/CRM1-dependent nucleocytoplasmatic traffic of Aven could modulate its ability to influence cell cycle progression.
[Expression of antiapoptotic gene aven in de novo acute myeloid leukemia patients and its clinical significance].
Chen et al., Guangzhou, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2009
the expression level of aven mRNA in de novo AML patients obviously increases
A recombinant MnSOD is radioprotective for normal cells and radiosensitizing for tumor cells.
Mancini et al., Napoli, Italy. In Free Radic Biol Med, 2009
activated in irradiated tissues protected from radiodamage by treatment with recombinant superoxide dismutase (MnSOD)
Aven-dependent activation of ATM following DNA damage.
Kornbluth et al., Durham, United States. In Curr Biol, 2008
These results identify Aven as a new ATM activator and describe a positive feedback loop operating between Aven and ATM; in aggregate, these findings place Aven, a known apoptotic inhibitor, as a critical transducer of the DNA-damage signal.
Adolescent sexuality and disability.
Thomas et al., New York City, United States. In Phys Med Rehabil Clin N Am, 2002
SIECCAN, 850 Coxwell, Aven., East York, Ontario, M4C 5R1 Tel: 416-466-5304; Fax: 416-778-0785.
share on facebooktweetadd +1mail to friends