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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


Top mentioned proteins: CAN, Aura, Histone, V1a, p53
Papers using Aurora antibodies
Update on Aurora kinase targeted therapeutics in oncology
Ulisse Salvatore et al., In BMC Cancer, 2010
... Mouse monoclonal antibodies against Aurora-A (31C1) and Aurora-B (AIM-1) were from Abcam (Cambridge, UK) ...
Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR
Hooijberg Erik et al., In Journal of Translational Medicine, 2008
... ] supplemented with 1% human serum (HS; ICN Biomedicals, Aurora, OH, USA) and antibiotics (100 IE/ml penicillin and 100 μg/ml streptomycin, Life technologies).
A conserved mechanism for steroid receptor translocation to the plasma membrane
Watson Cheryl S et al., In Environmental Health, 2006
... purchased from Cell Signaling Technology (Danvers, MA), for clathrin (mouse anti-clathrin monoclonal) from ICN Biomedicals (Aurora, OH), for ERα (MC-20) from Santa Cruz Biotechnology (Santa Cruz, CA), for ...
The structure and regulation of vinculin
Beaulieu Jean-François et al., In Journal of Cellular Physiology, 2005
... All other materials were purchased from Sigma–Aldrich, MP Biomedicals (Aurora, OH), BD Biosciences (San Jose, CA), or ...
Swi6/HP1 recruits a JmjC domain protein to facilitate transcription of heterochromatic repeats
Dillon Niall et al., In The EMBO Journal, 2005
... ), α-H3K9me3 (Upstate 07-442), α-Aurora B (Abcam ab2254), α-HP1β (anti-M31 rat ...
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Papers on Aurora
Multifunctional Human Transcriptional Co-activator Protein PC4 is a Substrate of Aurora Kinases and Activates the Aurora Enzymes.
Kundu et al., Bengaluru, India. In Febs J, Feb 2016
A fraction of PC4 associates with Aurora A and Aurora B and undergoes phosphorylation, following which, PC4 activates both Aurora A and B to sustain optimal kinase activity to maintain the phosphorylation gradient for the proper functioning of the mitotic machinery.
Benzimidazole-Based Quinazolines: In Vitro Evaluation, Quantitative Structure-Activity Relationship, and Molecular Modeling as Aurora Kinase Inhibitors.
Paul et al., Patiāla, India. In Arch Pharm (weinheim), Feb 2016
The ligand efficiency (LE) of the compounds with Aurora A kinase was also determined.
Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression.
Machado-Santelli et al., São Paulo, Brazil. In Oncotarget, Feb 2016
It was observed mislocalization of Anillin, Aurora B, Septin 9 and Alix in the intercellular bridge, and no determination of secondary constriction and abscission sites.
The Anaphase-Promoting Complex/Cyclosome Is Essential for Entry into Meiotic M-Phase.
Mayer et al., Konstanz, Germany. In Dev Cell, Feb 2016
Preventing PP6c destruction impairs activating autophosphorylation of Aurora A, a cell-cycle kinase critical for meiotic translation.
Regulation of steroid hormone receptors and coregulators during the cell cycle highlights potential novel function in addition to roles as transcription factors.
Murphy et al., Winnipeg, Canada. In Nucl Recept Signal, Dec 2015
Cell cycle progression is tightly controlled by several kinase families including Cyclin-Dependent Kinases, Polo-Like Kinases, and Aurora Kinases.
Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype.
Liu et al., Dalian, China. In Nat Commun, Dec 2015
Centrosome-localized mitotic Aurora kinase A (AURKA) facilitates G2/M events.
A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis.
Diskin et al., Philadelphia, United States. In Cancer Cell, Dec 2015
Further, we demonstrate a convergence of LIN28B and RAN signaling on Aurora kinase A activity.
Phase II Intergroup Trial of Alisertib in Relapsed and Refractory Peripheral T-Cell Lymphoma and Transformed Mycosis Fungoides: SWOG 1108.
Friedberg et al., Seattle, United States. In J Clin Oncol, Aug 2015
PURPOSE: Aurora A kinase (AAK) is upregulated in highly proliferative lymphomas, suggesting its potential as a therapeutic target.
GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.
Seemann et al., Dallas, United States. In Cell, Aug 2015
Sequestration of importin α by GM130 liberates the spindle assembly factor TPX2, which activates Aurora-A kinase and stimulates local microtubule nucleation.
A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA.
Dominguez et al., Aurora, United States. In Lancet, May 2015
METHODS: We defined a case of neurological disease as any child admitted to Children's Hospital Colorado (Aurora, CO, USA) with acute flaccid paralysis with spinal-cord lesions involving mainly grey matter on imaging, or acute cranial nerve dysfunction with brainstem lesions on imaging, who had onset of neurological symptoms between Aug 1, 2014, and Oct 31, 2014.
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.
Ellenberg et al., Heidelberg, Germany. In Nat Biotechnol, Apr 2015
We also analyzed the cell-cycle-dependent dynamics of the mitotic kinase complex Aurora B/INCENP and showed how a rise in Aurora concentration triggers two-step complex formation.
Aurora-A Kinase as a Promising Therapeutic Target in Cancer.
Galanis et al., Rochester, United States. In Front Oncol, 2014
Among the three members of the Aurora kinase family (Aurora-A, -B, and -C), Aurora-A and Aurora-B are expressed at detectable levels in somatic cells undergoing mitotic cell division.
Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly.
Guarguaglini et al., Roma, Italy. In Front Oncol, 2014
The Aurora kinase A (AURKA) is involved in different aspects of mitotic control, from mitotic entry to cytokinesis.
Aurora A's Functions During Mitotic Exit: The Guess Who Game.
Prigent et al., Rennes, France. In Front Oncol, 2014
Until recently, the knowledge of Aurora A kinase functions during mitosis was limited to pre-metaphase events, particularly centrosome maturation, G2/M transition, and mitotic spindle assembly.
Phenotypic Screening Approaches to Develop Aurora Kinase Inhibitors: Drug Discovery Perspectives.
Lallena et al., Alcobendas, Spain. In Front Oncol, 2014
Targeting mitotic regulators as a strategy to fight cancer implies the development of drugs against key proteins, such as Aurora-A and -B.
Aurora A contributes to p150(glued) phosphorylation and function during mitosis.
Giet et al., Rennes, France. In J Cell Biol, 2010
Drosophila melanogaster aurora A phosphorylates the dynactin subunit p150(glued) on sites required for its association with the mitotic spindle.
Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells.
Doe et al., Eugene, United States. In Cell, 2009
Study identified a previously unrecognized evolutionarily conserved Pins domain (Pins(LINKER)) that requires Aurora-A phosphorylation to recruit Dlg and promote partial spindle orientation.
Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.
Knoblich et al., Vienna, Austria. In Cell, 2008
Study shows that a phosphorylation cascade triggered by the activation of Aurora-A is responsible for the asymmetric localization of Numb in mitosis.
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts.
Chia et al., Singapore, Singapore. In Genes Dev, 2007
Study shows that Aurora-A acts as a tumor suppressor by suppressing neuroblast self-renewal and promoting neuronal differentiation.
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.
Doe et al., Eugene, United States. In Genes Dev, 2007
Study concludes that Aurora-A and Numb are novel inhibitors of neuroblast self-renewal and that spindle orientation regulates neuroblast self-renewal.
More papers using Aurora antibodies
KIF14 and citron kinase act together to promote efficient cytokinesis
Barr Francis A. et al., In The Journal of Cell Biology, 2004
... Antibodies were obtained as follows: mouse monoclonals to α-tubulin (clone DM1a; Sigma-Aldrich); Aurora B (clone AIM-1; Becton Dickinson); mouse monoclonal to citron ...
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis
Zachos George et al., In The Journal of Cell Biology, 2000
... antiserum was generated in rabbits by immunization against the phosphorylated peptide pS331 (H2N-CPWVRANS[PO3H2]RRVLPPS-CONH2) of human Aurora B (Eurogentec).
Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis
Lo K-W et al., In Oncogene, 2000
... To inhibit the Aurora activity, cells were treated with 2 μ ZM447439 (Tocris Bioscience, Bristol, UK) or ...
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2
Barr Francis A. et al., In The Journal of Cell Biology, 2000
... ); AIM-1 0.25 mg/ml mouse monoclonal to Aurora B (Becton Dickinson); affinity purified 0.1 mg/ml ...
A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus.
Maedler Kathrin, In PLoS ONE, 1997
... France), PDX1 antibody from Millipore (St Quentin en Yvelines, France), insulin antibody from MP Biomedicals (Aurora, Ohio, USA), CK 20 antibody from Abcam (Paris, France) and Glut ...
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
Gruneberg Ulrike et al., In The Journal of Cell Biology, 1997
... antibodies were used to α-tubulin (mouse DM1A; Sigma-Aldrich), Plk1 (mouse SC-17783; Santa Cruz Biotechnology, Inc.), Aurora A (rabbit AB12875; Abcam), Aurora A pT288 (rabbit 3079; ...
Methods for clonal growth and serial cultivation of normal human epidermal keratinocytes and mesothelial cells.
Karl Mike O., In PLoS ONE, 1988
... anti-cyclin A2 (CY-A1, Sigma-Aldrich, Inc.), anti PCNA (167, Sigma-Aldrich, Inc.), anti-γ-tubulin (GTU-88; Sigma-Aldrich, Inc.), anti Aurora kinase B (Abcam), anti Keratin 1,10,11 (Ks ...
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
Hyman Anthony A. et al., In The Journal of Cell Biology, 1987
... Full-length Aurora A cDNA was subcloned into pET21 vector (CLONTECH Laboratories, Inc.) for ...
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