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Carnosine synthase 1

CARNS1 (EC, a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).[supplied by OMIM, Apr 2010] (from NCBI)
Top mentioned proteins: OUT, fibrillin-1
Papers on ATPGD1
Expression profiles of carnosine synthesis-related genes in mice after ingestion of carnosine or ß-alanine.
Morimatsu et al., Tsukuba, Japan. In J Int Soc Sports Nutr, 2011
Therefore, we investigated the tissue distribution of carnosine synthase, ATP-grasp domain-containing protein-1 (ATPGD1) mRNA, and ATPGD1 and carnosine specific dipeptidase (CN1) gene expression profiles in mice that were given carnosine or ß-alanine orally.
Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1).
Van Schaftingen et al., Brussels, Belgium. In J Biol Chem, 2010
carnosine synthase is identified as ATP-grasp domain-containing protein 1
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