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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Activating transcription factor 5

ATF5, activating transcription factor 5
plays a role in inhibition of nerve growth factor-induced neuronal outgrowth and regulation of neurogenesis [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: GDNF, V1a, ATF4, CREB, ACID
Papers using ATF5 antibodies
Identification and characterization of the promoter of human ATF5 gene
Angelastro J M et al., In Oncogene, 2009
... One pBiTETO-d/n-ATF5 transgenic B6CBA/F1 mouse was able ...
Papers on ATF5
Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction.
Mizuguchi et al., Ōsaka, Japan. In Biochem Biophys Res Commun, Feb 2016
Because the gene expression levels of the hepatic transcription factors (activating transcription factor 5 (ATF5), CCAAT/enhancer-binding protein alpha (c/EBPα), and prospero homeobox protein 1 (PROX1)) in adult liver were significantly higher than those in human iPS-HLCs and fetal liver, we expected that the hepatic functions of human iPS-HLCs could be enhanced by adenovirus (Ad) vector-mediated ATF5, c/EBPα, and PROX1 transduction.
Potential Role of Activating Transcription Factor 5 during Osteogenesis.
Memeo et al., Italy. In Stem Cells Int, Dec 2015
Activating transcription factor 5 is a transcription factor of the ATF/cAMP response element-binding protein (CREB) family.
Elucidation and pharmacological targeting of novel molecular drivers of follicular lymphoma progression.
Califano et al., Colombia. In Cancer Res, Dec 2015
This analysis revealed FOXM1, TFDP1, ATF5, HMGA1, and NFYB to be candidate master regulators (MR) contributing to disease progression.
Association between human cytomegalovirus infection and histone acetylation level in various histological types of glioma.
Wang et al., Qingdao, China. In Oncol Lett, Nov 2015
The in situ protein expression of IE86, which is encoded by the IE2 gene, activating transcription factor 5 (ATF5), P300, acetyl-histone H3K9 and acetyl-histone H3K14 was detected by immunohistochemistry.
The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map.
Bohm et al., Umeå, Sweden. In J Neurosci, Nov 2015
Initially, these effects are selective to the VL-most zone and correlate with reduced ATF5 expression and accumulation of OSNs that do not express ORs.
Activating transcription factor 5 (ATF5) is essential for the maturation and survival of mouse basal vomeronasal sensory neurons.
Takahashi et al., Hachiōji, Japan. In Cell Tissue Res, Oct 2015
UNASSIGNED: Activating transcription factor 5 (ATF5) is a member of the CREB/ATF family of transcription factors, which is highly expressed in olfactory chemosensory tissues, the main olfactory epithelium and vomeronasal epithelium (VNE) in mice.
DNA methylation level of promoter region of activating transcription factor 5 in glioma.
Wang et al., Qingdao, China. In J Zhejiang Univ Sci B, Sep 2015
Previous researches have shown that the expression level of activating transcription factor 5 (ATF5) was frequently increased in glioma and its acetylation level was related to glioma.
ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole.
Liu et al., Spokane, United States. In Cell, Aug 2015
Here, we show that ATF5 forms a characteristic 9-fold symmetrical ring structure in the inner layer of the PCM outfitting the proximal end of the mother centriole.
Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner.
Kögel et al., Frankfurt am Main, Germany. In Neoplasia, Jul 2015
Lentiviral knockdown of the activating transcription factor 5 combined with subsequent quantitative polymerase chain reaction analysis revealed that sorafenib-dependent suppression of MCL1 occurred at the transcriptional level but did not depend on activating transcription factor 5 which previously had been proposed to be essential for MCL1-dependent glioma cell survival.
Gene Expression Profiles of Main Olfactory Epithelium in Adenylyl Cyclase 3 Knockout Mice.
Ma et al., Baoding, China. In Int J Mol Sci, 2014
Quantitative RT-PCR verification of the differentially expressed epigenetic regulation related genes, olfactory receptors, ion transporter related genes, neuron development and differentiation related genes, lipid metabolism and membrane protein transport etc. related genes showed that P75NTR, Hinfp, Gadd45b, and Tet3 were significantly up-regulated, while Olfr370, Olfr1414, Olfr1208, Golf, Faim2, Tsg101, Mapk10, Actl6b, H2BE, ATF5, Kirrrel2, OMP, Drd2 etc. were significantly down-regulated.
Human hepatocytes with drug metabolic function induced from fibroblasts by lineage reprogramming.
Deng et al., Beijing, China. In Cell Stem Cell, 2014
Here, we show that functional human induced hepatocytes (hiHeps) can be generated from fibroblasts by overexpressing the hepatic fate conversion factors HNF1A, HNF4A, and HNF6 along with the maturation factors ATF5, PROX1, and CEBPA.
Co-opting the unfolded protein response to elicit olfactory receptor feedback.
Lomvardas et al., San Francisco, United States. In Cell, 2013
OR expression induces Perk-mediated phosphorylation of the translation initiation factor eif2α causing selective translation of activating transcription factor 5 (ATF5).
ATF5, a possible regulator of osteogenic differentiation in human adipose-derived stem cells.
Hutmacher et al., Singapore, Singapore. In J Cell Biochem, 2012
The evidence suggests a role for ATF5 in the regulation of osteogenic differentiation in adipose-derived stem cells.
Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells.
Liu et al., State College, United States. In J Biol Chem, 2012
a mechanistic link between elevated NPM1 expression and depressed ATF5 in HCC and suggests that regulation of ATF5 by NPM1 plays an important role in the proliferation and survival of HCC.
Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells.
Greene et al., New York City, United States. In Dev Neurobiol, 2012
These findings indicate a reciprocal interaction between ATF5 and Shh in which Shh stimulates ATF5 expression and in which ATF5 contributes to Shh-stimulated cerebellar granule neuron progenitor cell expansion.
ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.
Krajinovic et al., Montréal, Canada. In Blood, 2011
ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.
p300-Dependent ATF5 acetylation is essential for Egr-1 gene activation and cell proliferation and survival.
Lu et al., Penn Hills, United States. In Mol Cell Biol, 2011
coordinated actions by ATF5, p300, Elk-1, and ERK/mitogen-activated protein kinase are essential for ATF5-dependent Egr-1 activation and cell proliferation and survival
A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications.
Green et al., Worcester, United States. In Nat Med, 2010
essential in malignant glioma genesis and ATF5-mediated survival pathway identified
The transcription factor ATF5: role in neurodevelopment and neural tumors.
Angelastro et al., New York City, United States. In J Neurochem, 2009
We review recent findings regarding the properties of ATF5 and the major roles that this transcription factor plays in development of the nervous system and in survival of neural tumors.
A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation.
Murry et al., Seattle, United States. In Cell Stem Cell, 2008
Transcripts under exclusive translational control included the transcription factor ATF5, the tumor suppressor DCC, and the beta-catenin agonist Wnt1.
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