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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Ataxin 7-like 3

Ataxin 7-like 3, ATXN7L3
Top mentioned proteins: Histone, USP22, H2A, DSS1, Domino
Papers on Ataxin 7-like 3
The Cellular Protein Complex Associated with a Transforming Region of E1A Contains c-MYC.
Chinnadurai et al., Saint Louis, United States. In J Virol, 2014
The same E1A region additionally interacted with the constituents of a deubiquitinase complex consisting of USP22, ATXN7, and ATXN7L3 via TRRAP.
The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements.
Tora et al., Illkirch-Graffenstaden, France. In Mol Cell Biol, 2011
Downregulation of ATXN7L3 by short hairpin RNA speci fi cally inactivated the SAGA deubiquitination activity, leading to a strong increase of global H2B ubiquitination and a moderate increase of H2A ubiquitination.
The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties.
Kieffer et al., Illkirch-Graffenstaden, France. In Embo Rep, 2010
The solution structures of the SCA7 domain of both ATXN7 and ATXN7L3 reveal a new, common zinc-finger motif at the heart of two distinct folds, providing a molecular basis for the observed functional differences.
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
Devys et al., Tokyo, Japan. In Mol Cell, 2008
ATXN7L3, USP22, & ENY2 are required cofactors for full transcriptional activity by nuclear receptors. The deubiquitinase activity of TFTC/STAGA HAT counteracts heterochromatin silencing & is a positive cofactor for in vivo nuclear receptor activation.
Genome-wide survey for biologically functional pseudogenes.
Lagergren et al., Stockholm, Sweden. In Plos Comput Biol, 2006
Two processed sequences are notable, their conservation since the human-mouse split being as high as most protein-coding genes; one is derived from the protein Ataxin 7-like 3 (ATX7NL3), and one from the Spinocerebellar ataxia type 1 protein (ATX1).
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