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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Angiotensin II receptor, type 1a

receptor for and mediator of vascular remodeling effects of angiotensin II [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Angiotensin II, Renin, V1a, CAN, AT2
Papers using AT1 antibodies
Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma
Oya M et al., In British Journal of Cancer, 2008
... Rabbit polyclonal antibody for VEGF and AT1R were purchased from Santa Cruz Biotechnology, Inc ...
Mechanisms of tubulointerstitial injury in IgA nephropathy
Lai Kar-Neng et al., In Journal of Translational Medicine, 2004
... Goat anti-CYP11B2, rabbit polyclonal anti-AT1R (AT1R) and AngII receptor subtype-II (AT2R) were from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Papers on AT1
Impact of Olmesartan Medoxomil on Amiodarone- Induced Pulmonary Toxicity in Rats: Focus on Transforming Growth Factor-ßeta-1.
Abd Allah et al., Banhā, Egypt. In Basic Clin Pharmacol Toxicol, Feb 2016
Several lines of evidence have suggested that AT1 receptor antagonists can attenuate pulmonary fibrosis in different animal models.
Monocytic Angiotensin and Endothelin Receptor Imbalance Modulate Secretion of the Profibrotic Chemokine Ligand 18.
Riemekasten et al., Lübeck, Germany. In J Rheumatol, Feb 2016
RESULTS: Monocytes of patients with SSc presented an increased angiotensin II Type 1 receptor (AT1R)/AT2R ratio compared with those of healthy donors.
Up-regulation of the Ang II /AT1 receptor may compensate for the loss of gastric antrum ICC via the PI3k/Akt signaling pathway in STZ-induced diabetic mice.
Xu et al., Shanghai, China. In Mol Cell Endocrinol, Feb 2016
However, the angiotensin receptor type 1 (AT1R) expression levels in gastric smooth muscle and angiotensin-converting enzyme (ACE) expression levels in gastric mucosa were increased.
Combined Angiotensin Receptor Modulation in the Management of Cardio-Metabolic Disorders.
Unger et al., Maastricht, Netherlands. In Drugs, Jan 2016
Consequently, RAS inhibition by ACE inhibitors or angiotensin AT1 receptor (AT1R) blockers is the evidence-based standard for cardiovascular risk reduction in high-risk patients, including diabetics with albuminuria.
Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension.
Nishida et al., Okazaki, Japan. In Sci Signal, Dec 2015
The angiotensin (Ang) type 1 receptor (AT1R) promotes functional and structural integrity of the arterial wall to contribute to vascular homeostasis, but this receptor also promotes hypertension.
Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats.
He et al., Shenyang, China. In Oxid Med Cell Longev, Dec 2015
Real-time RT-PCR analysis revealed that DOCA/NaCl enhanced the mRNA expression of hypertensive components including AT1-R, ACE-1, and TNF-α in the paraventricular nucleus of hypothalamus in both intact and OVX females.
Vascular endothelial dysfunction and pharmacological treatment.
Su, Maisons-Alfort, France. In World J Cardiol, Dec 2015
Experimental and clinical studies have demonstrated that a variety of currently used or investigational drugs, such as angiotensin-converting enzyme inhibitors, angiotensin AT1 receptors blockers, angiotensin-(1-7), antioxidants, beta-blockers, calcium channel blockers, endothelial NO synthase enhancers, phosphodiesterase 5 inhibitors, sphingosine-1-phosphate and statins, exert endothelial protective effects.
The Role of Renin Angiotensin Aldosterone System Genes in Diabetic Nephropathy.
Rahimi, Kermānshāh, Iran. In Can J Diabetes, Dec 2015
The effects of some RAAS gene variants, including angiotensin converting enzyme (ACE), angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R), on the risk for DN have been studied more extensively, but there has been controversy.
International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].
Thomas et al., Seychelles. In Pharmacol Rev, Oct 2015
The receptors for RAS peptides consist of three G-protein-coupled receptors—the angiotensin II type 1 receptor (AT1 receptor), the angiotensin II type 2 receptor (AT2 receptor), the MAS receptor—and a type II trans-membrane zinc protein—the candidate angiotensin IV receptor (AngIV binding site).
Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.
Amoli et al., Tehrān, Iran. In J Diabetes Res, 2014
We found significant association between CTLA-4, IL-18, VDR, TAP2, IL-12, and CD4 genes and T1DM, HNFα and MODY, haptoglobin, paraoxonase, leptin, TCF7L2, calreticulin, ERα, PPAR-γ2, CXCL5, calpain-10, IRS-1 and 2, GSTM1, KCNJ11, eNOS, VDR, INSR, ACE, apoA-I, apo E, adiponectin, PTPN1, CETP, AT1R, resistin, MMP-3, BChE K, AT2R, SUMO4, IL-10, VEGF, MTHFR, and GSTM1 with T2DM or its complications.
Reactive Oxygen Species in the Paraventricular Nucleus of the Hypothalamus Alter Sympathetic Activity During Metabolic Syndrome.
Braga et al., João Pessoa, Brazil. In Front Physiol, 2014
The PVN plays an important role in the sympathoexcitatory response to increasing circulating levels of angiotensin II (Ang-II), which activates AT1 receptors in the circumventricular organs (OCVs), mainly in the subfornical organ (SFO).
The angiotensin II type 2 receptor for pain control.
Anand et al., Rotterdam, Netherlands. In Cell, 2014
All well-known deleterious effects of angiotensin (Ang) II, including vasoconstriction, inflammation, water and salt retention, and vascular remodeling, are mediated via its type 1 (AT1) receptor.
Alveolar progenitor and stem cells in lung development, renewal and cancer.
Krasnow et al., Stanford, United States. In Nature, 2014
Classical studies suggested that AT1 arise from AT2 cells, but recent studies propose other sources.
AT1a receptor signaling is required for basal and water deprivation-induced urine concentration in AT1a receptor-deficient mice.
Zhuo et al., Jackson, United States. In Am J Physiol Renal Physiol, 2012
AT(1a) receptor-mediated ANG II signaling is required to maintain tonic AVP release and regulate V(2) receptor-mediated responses to water deprivation in the inner medulla.
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
Lu et al., Shanghai, China. In Regul Pept, 2012
Ang-(1-7) and Ang II specifically interact with each other on rat renal mesangial cells via activation of their specific receptors, Mas and AT1 receptor respectively.
Allosteric interactions within the AT₁ angiotensin receptor homodimer: role of the conserved DRY motif.
Hunyady et al., Budapest, Hungary. In Biochem Pharmacol, 2012
allosteric interactions in the homodimers of ATR significantly affect the function of the non-stimulated protomer, and the conserved DRY motif has a crucial role in these interactions.
Possible involvement of angiotensin-converting enzyme 2 and Mas activation in inhibitory effects of angiotensin II Type 1 receptor blockade on vascular remodeling.
Horiuchi et al., Japan. In Hypertension, 2012
Data show that in angiotensin II type 1a receptor knockout mice, mRNA expression and immunostaining of ACE2 and Mas in the injured artery were greater, with less neointimal formation than in wild-type mice.
The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary.
Stepien et al., Łódź, Poland. In Scientificworldjournal, 2011
angiotensin type 1 and type 2 receptors are involved in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary
Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism.
Dietz et al., Baltimore, United States. In Science, 2011
Angiotensin II (AngII) mediates progression of aortic aneurysm, but the relative contribution of its type 1 (AT1) and type 2 (AT2) receptors remains unknown.
AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.
Coffman et al., Durham, United States. In Cell Metab, 2011
Abrogation of AT(1) angiotensin receptor signaling in the proximal tubule alone is sufficient to lower BP, despite intact vascular responses.
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