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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

DNA cross-link repair 1C

Artemis, a SCID, MART, phosphoribosylpyrophosphate synthetase, ARTS
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: MART-1, CAN, HAD, CD8, V1a
Papers on Artemis
Validity and Clinical Utility of Subtyping by the Beck Depression Inventory in Women Seeking Gastric Bypass Surgery.
Grilo et al., New Haven, United States. In Obes Surg, Feb 2016
When identifying clinical severity, however, subtyping women by BDI scores of >15 may identify a significantly more disturbed subgroup than relying on a SCID-I/P-generated mood disorder diagnosis.
Modulation of oxidative stress, inflammation, autophagy and expression of Nrf2 in hippocampus and frontal cortex of rats fed with açaí-enriched diets.
Shukitt-Hale et al., In Nutr Neurosci, Feb 2016
In this study, two different species of açaí pulp extracts, naturally grown in two distinct regions of the Amazon, namely, Euterpe oleracea Mart.
Liver metabolic and histopathological profile in finishing lambs fed licuri (Syagrus coronata(Mart.)Becc.) cake.
de Cruz et al., Salvador, Brazil. In Trop Anim Health Prod, Feb 2016
UNASSIGNED: The objective of this study was to determine the impact of including licuri cake in the diet of Santa Inês crossbred finishing lambs by examining their liver metabolic and histopathological profile.
Comparison of functional limbal epithelial stem cell isolation methods.
Calonge et al., Valladolid, Spain. In Exp Eye Res, Jan 2016
Endothelial cell (PECAM), melanocyte (MART-1), and dendritic cell (CD11c) proteins were not detected, while fibroblast-protein (S100A4) was detected in all LPCs.
Usefulness of Highly Sensitive Troponin as a Predictor of Short-Term Outcome in Patients With Diabetes Mellitus and Stable Coronary Artery Disease (from the ARTEMIS Study).
Junttila et al., Oulu, Finland. In Am J Cardiol, Jan 2016
UNASSIGNED: The aim of this study was to test the hypothesis that novel biomarkers may predict cardiac events in diabetic patients with stable coronary artery disease (CAD).
E3 ubiquitin ligases as molecular targets in human oral cancers.
Kitagawa et al., Hamamatsu, Japan. In Curr Cancer Drug Targets, Dec 2015
SCFSkp2, KPC complex, Pirh2 and CRL4DDB2-Artemis have been reported as E3 ligases targeting p27Kip1 for degradation.
Spitz nevus arising in the eyelid of a teenager.
Yoon et al., Philadelphia, United States. In Surv Ophthalmol, Nov 2015
HMB-45, MART-1, and microphthalmia-associated transcription factor were all positive and established the melanocytic nature of the benign tumor.
Congenital defects in V(D)J recombination.
de Villartay, Paris, France. In Br Med Bull, Jun 2015
Two NHEJ factors, Artemis and XLF/Cernunnos, were identified through the molecular studies of SCID patients.
Rezolsta® (Darunavir/Cobicistat): First Boosted Protease Inhibitor Co-formulated with Cobicistat.
Moltó et al., Barcelona, Spain. In Aids Rev, Apr 2015
Data from the single-arm, open-label, phase III GS-US-216-130 trial showed virological efficacy rates comparable to those from ARTEMIS and ODIN.
Regulation of Cell Death by IAPs and Their Antagonists.
Ryoo et al., New York City, United States. In Curr Top Dev Biol, 2014
Loss of the mammalian IAP-antagonist ARTS results in reduced stem cell apoptosis.
Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naive melanoma.
Chen et al., Princeton, United States. In J Clin Oncol, 2014
High pretreatment NY-ESO-1 and MART-1-specific CD8(+) T cells were associated with progression of disease.
Sept4/ARTS regulates stem cell apoptosis and skin regeneration.
Steller et al., New York City, United States. In Science, 2013
We found that mice deficient for the proapoptotic Sept4/ARTS gene have elevated numbers of hair follicle stem cells (HFSCs) that are protected against apoptosis.
Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells.
Kawamoto et al., Yokohama, Japan. In Cell Stem Cell, 2013
In this study, we established iPSCs from mature cytotoxic T cells specific for the melanoma epitope MART-1.
Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs.
Cortes et al., New York City, United States. In J Exp Med, 2012
Point mutations in Artemis that disrupt its interaction with Ligase IV or DNA-PKcs reduce V(D)J recombination.
Similar temporal and spatial recruitment of native 19S and 20S proteasome subunits to transcriptionally active chromatin.
Tansey et al., Nashville, United States. In Proc Natl Acad Sci U S A, 2012
Data show that proteasome subunits Rpt1, Rpt4, Rpn8, Rpn12, Pre6, and Pre10 are recruited to GAL10 rapidly upon galactose induction.
Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS-I.
de Brouwer et al., Cleveland, United States. In Am J Med Genet A, 2012
missense mutations in PRPS1 can cause a continuous spectrum of features ranging from progressive non-syndromic postlingual hearing impairment to uric acid overproduction, and recurrent infections depending on the functional sites that are affected
Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27.
Legerski et al., Houston, United States. In Cell Cycle, 2012
Regulation of p27 by Artemis and DDB2 is important for cell cycle progression in normally proliferating cells.
Molecular analysis of X-linked inborn errors of purine metabolism: HPRT1 and PRPS1 mutations.
Fujimori et al., Japan. In Nucleosides Nucleotides Nucleic Acids, 2011
Three HPRT1 mutations in Lesch-Nyhan families were identified but no mutation was identified in any patient in the analysis of PRPS1.
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Sleckman et al., United States. In Nature, 2011
Although there are several cellular nucleases that could perform this function, only the Artemis nuclease is able to do so efficiently.
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.
Melief et al., Leiden, Netherlands. In Nat Immunol, 2011
Nardilysin and TOP were required, either together or alone, for the generation of a tumor-specific CTL epitope from PRAME, an immunodominant CTL epitope from Epstein-Barr virus protein EBNA3C, and a clinically important epitope from the melanoma protein MART-1.
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