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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

ADP-ribosylation factor-like 11

This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010] (from NCBI)
Top mentioned proteins: iMpact, OUT, PrP, bcl-2, caspase-3
Papers on ARLTS1
ARLTS1 and prostate cancer risk--analysis of expression and regulation.
Schleutker et al., Tampere, Finland. In Plos One, 2012
Recently, we showed that homozygous carriers for the T442C variant of the ARLTS1 gene (ADP-ribosylation factor-like tumour suppressor protein 1 or ARL11, located at 13q14) are associated with an increased risk for both unselected and familial PCa.
Involvement of ARLTS1 in chemotherapy and apoptosis in ovarian cancer cell line.
Peng et al., Chengdu, China. In Arch Gynecol Obstet, 2011
PURPOSE: Recent evidence suggests that ADP-ribosylation factor-like tumor suppressor gene 1(ARLTS1) may act as a tumor suppressor gene.
ARLTS1, MDM2 and RAD51 gene variations are associated with familial breast cancer.
Dalay et al., ─░stanbul, Turkey. In Mol Biol Rep, 2011
The role of the allelic variants in ARLTS1, RAD51 and MDM2 acting in the tumor suppressor, DNA repair and p53 pathways as risk factors for familial breast cancer in 147 patients displaying characteristics of familial disease, was investigated.
Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.
Schleutker et al., Tampere, Finland. In Plos One, 2010
the important role of ARLTS1 Cys148Arg variant as a contributor in prostate cancer predisposition
[Polymorphism of ARLTS1 gene in early-onset ovarian cancer].
Peng et al., Chengdu, China. In Sichuan Da Xue Xue Bao Yi Xue Ban, 2009
A significantly increased risk was observed for young ovarian cancer patients with ARLTS1 Cys148Arg variant.
Association of the ARLTS1 variants with familial ovarian cancer risk in China.
Peng et al., Chengdu, China. In Int J Gynecol Cancer, 2009
Data show a significantly increased risk of familial OC for ARLTS1 Cys148Arg variant, which indicate that ARLTS1 may play a role in familial ovarian cancer.
[Effects of ARLTS1 gene on growth and apoptosis of epithelial ovarian cancer SKOV3 cells].
Peng et al., Chengdu, China. In Sichuan Da Xue Xue Bao Yi Xue Ban, 2009
OBJECTIVE: To investigate the effect of ARLTS1 (ADP-ribosylation factor-like tumor suppressor gene 1) on the growth and apoptosis of ovarian cystadenocarcinoma cell line SKOV3.
ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer.
Vahteristo et al., Tampere, Finland. In Eur J Hum Genet, 2008
ARLTS1 germline variants are not associated with breast, prostate, and colorectal cancer
ARLTS1 - a novel tumor suppressor gene.
Calin et al., Buffalo, United States. In Cancer Lett, 2008
A novel tumor suppressor gene [ARLTS1 (ADP-ribosylation factor-like tumor suppressor gene 1)]is found to be altered in human carcinogenesis. It is located in Chromosome 13q14.3.
Tumor suppressor functions of ARLTS1 in lung cancers.
Calin et al., United States. In Cancer Res, 2007
650 transcripts expressed after restoration of ARLTS1 expression were identified in A549 cells, suggesting that pathways involved in cell survival, proliferation, signaling, and development mediate the effects of wild-type ARLTS1 in lung cancer.
Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer.
Gastrointestinal Oncology Group of the Spanish Gastroenterological Association et al., Barcelona, Spain. In Carcinogenesis, 2007
Cysteine148Arginine variant is associated with a moderately increased risk of colorectal cancer, both in sporadic and familial cases.
ARLTS1 polymorphisms and basal cell carcinoma of the skin.
Kumar et al., Heidelberg, Germany. In Hered Cancer Clin Pract, 2006
Polymorphisms in the ARLTS1 gene, a member of the Ras super-family, have been associated with susceptibility in different cancer types.
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
Croce et al., Columbus, United States. In Cancer Res, 2006
ARLTS1 is a tumor suppressor gene initially described as a low-penetrance cancer gene: a truncated Trp149Stop (MUT) polymorphism is associated with general familial cancer aggregation and, particularly, high-risk familial breast cancer.
ARLTS1 variants and melanoma risk.
Burwinkel et al., Heidelberg, Germany. In Int J Cancer, 2006
While ARLTS1 Trp149Stop did not influence melanoma risk (OR = 0.83, 95% CI = 0.37-1.88, p = 0.65), Cys148Arg revealed a statistically significant association with an increased risk for heterozygous carriers (OR = 1.43, 95% CI = 1.05-1.95, p = 0.02)
Familial cancer associated with a polymorphism in ARLTS1.
Croce et al., Philadelphia, United States. In N Engl J Med, 2005
A genetic variant of ARLTS1 predisposes patients to familial cancer.
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