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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Apolipoprotein M

apoM, apolipoprotein M, G3A
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012] (from NCBI)
Top mentioned proteins: HDL, HAD, CAN, AGE, ACID
Papers using apoM antibodies
Simvastatin promotes atherosclerotic plaque stability in apoE-deficient mice independently of lipid lowering
Xu Ning et al., In Lipids in Health and Disease, 2001
... Rabbit anti-mouse apoM was from Abnova Corporation, Taiwan ...
Papers on apoM
Dietary intake in Japanese patients with kidney transplantation.
Kanno et al., Tokyo, Japan. In Clin Exp Nephrol, Feb 2016
One patient was CKD G1 stage, five in G2, 17 in G3a, 24 in G3b, 14 in G4, and one in G5.
Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43.
Kwak et al., Copenhagen, Denmark. In Cardiovasc Res, Feb 2016
METHODS AND RESULTS: Apolipoprotein M (ApoM) transgenic (Apom-Tg) mice, in which plasma S1P is increased by 296%, and wild-type (WT) mice were subjected to in vivo I/R.
Urinary apolipoprotein M as a biomarker of acute kidney injury in children undergoing heart surgery.
Nielsen et al., Copenhagen, Denmark. In Biomark Med, Jan 2016
AIM: To investigate whether apoM is excreted in urine of children undergoing heart surgery and the potential of apoM as early biomarker of acute kidney injury (AKI).
HIV infection and hepatitis C virus genotype 1a are associated with phylogenetic clustering among people with recently acquired hepatitis C virus infection.
Applegate et al., Sydney, Australia. In Infect Genet Evol, Jan 2016
Among 225 participants with available Core-E2 sequence (ATAHC, n=113; HITS-p, n=90; and HITS-c, n=22), HCV genotype prevalence was: G1a: 38% (n=86), G1b: 5% (n=12), G2a: 1% (n=2), G2b: 5% (n=11), G3a: 48% (n=109), G6a: 1% (n=2) and G6l 1% (n=3).
Meta-Analysis on the Correlation Between APOM rs805296 Polymorphism and Risk of Coronary Artery Disease.
Zhang et al., Beijing, China. In Med Sci Monit, Dec 2015
BACKGROUND The present meta-analysis aimed to summarize the inconsistent findings on the association of apolipoprotein M gene (ApoM) rs805296 polymorphism with the risk of coronary artery disease (CAD), and to obtain a more authentic result about this topic.
Apolipoprotein M: Research progress, regulation and metabolic functions (Review).
Zhang et al., Wuhu, China. In Mol Med Report, Aug 2015
Apolipoprotein M (ApoM) is a novel lipoprotein-associated plasma protein of the apolipoprotein family.
HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation.
Hla et al., New York City, United States. In Nature, Aug 2015
Although the majority of plasma S1P is bound to apolipoprotein M (ApoM) in the high-density lipoprotein (HDL) particle, the immunological functions of the ApoM-S1P complex are unknown.
Apolipoprotein M.
Yi et al., Hengyang, China. In Clin Chim Acta, Jul 2015
Apolipoprotein M (ApoM) is a novel apolipoprotein that was discovered in 1999 and is bound primarily to high-density lipoproteins (HDLs) in the plasma.
The necessity and effectiveness of mineralocorticoid receptor antagonist in the treatment of diabetic nephropathy.
Sato, Tokyo, Japan. In Hypertens Res, Jun 2015
However, in category G3a and higher, sufficient attention must be paid to hyperkalemia.
HDL-S1P: cardiovascular functions, disease-associated alterations, and therapeutic applications.
Levkau, Essen, Germany. In Front Pharmacol, 2014
The main binding partner of S1P in HDL is apolipoprotein M but others may also exist particularly under conditions of acute S1P elevations.
Network-assisted analysis of primary Sjögren's syndrome GWAS data in Han Chinese.
Wang et al., Beijing, China. In Sci Rep, 2014
Of these pSS candidates, 14 genes had been reported to be associated with any of pSS, RA, and SLE, including STAT4, GTF2I, HLA-DPB1, HLA-DRB1, PTTG1, HLA-DQB1, MBL2, TAP2, CFLAR, NFKBIE, HLA-DRA, APOM, HLA-DQA2 and NOTCH4.
[Investigation by young members--comprehensive remarks as a chairman].
Kubota, In Rinsho Byori, 2014
The first speaker was Dr. Kurano from The University of Tokyo, and he discussed the crucial role of apolipoprotein M in "sphingosine 1-phosphatology".
ABCA1 upregulating apolipoproein M expression mediates via the RXR/LXR pathway in HepG2 cells.
Xu et al., Changzhou, China. In Biochem Biophys Res Commun, 2012
The present study demonstrated that apoM expression could be elevated by ABCA1 via the RXR/LXR pathway and LRH1 does not involve in the regulation of apoM by the activation of ABCA1, although the direct regulative pathway(s) between ABCA1 and apoM gene is still unknown yet.
Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL.
Nielsen et al., Copenhagen, Denmark. In Atherosclerosis, 2012
ApoM can bind oxidized phospholipids, increasing the antioxidant effect of HDL.
Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism.
von Eckardstein et al., Zürich, Switzerland. In Atherosclerosis, 2011
Report plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism.
Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis.
Chung et al., Seoul, South Korea. In Exp Mol Med, 2011
Single Nucleotide Polymorphism at the promoter region of the APOM gene is associated with rheumatoid arthritis.
Enchanced levels of apolipoprotein M during HBV infection feedback suppresses HBV replication.
Zhou et al., Wuhan, China. In Lipids Health Dis, 2010
Raised ApoM levels in hepatitis B virus (HBV) infection may in turn suppress HBV replication
Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis.
Stoffel et al., New York City, United States. In Nat Med, 2005
Overexpression of apoM in Ldlr(-/-) mice protected against atherosclerosis when the mice were challenged with a cholesterol-enriched diet.
Induction of MHC class I expression by the MHC class II transactivator CIITA.
Ting et al., Chapel Hill, United States. In Immunity, 1997
The G3A cell line, which is defective in CIITA induction, does not induce MHC class I antigen and promoter in response to IFNgamma.
Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction.
Ting et al., Chapel Hill, United States. In Immunity, 1994
Using one IFN gamma mutant cell line (G3A) that is selectively defective in HLA-DR and Ii induction, four lines of evidence are presented to show that CIITA mediates the IFN gamma induction of HLA-DR and Ii genes.
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