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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

PGCP plasma glutamate carboxypeptidase

encodes proline iminopeptidase (from NCBI)
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Top mentioned proteins: ACID, CAN, CD13, HAD, Angiotensin II
Papers on aminopeptidase
A biosensor platform for rapid detection of E. coli in drinking water.
Abbaszadegan et al., Tempe, United States. In Enzyme Microb Technol, Feb 2016
Non-target substrates that included 4-methylumbelliferyl-β-d-galactopyranoside (MUGal) and l-leucine β-naphthylamide aminopeptidase (LLβ-N) were also investigated to identify nonspecific patterns of enzymatic activities in E. coli.
Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump.
Nikaido et al., Monserrato, Italy. In Proc Natl Acad Sci U S A, Feb 2016
Because the hydrolysis of PAβN in Escherichia coli was nearly entirely dependent on an aminopeptidase, PepN, expression of PepN in periplasm allowed us to carry out a quantitative determination of PAβN efflux kinetics through the determination of its periplasmic concentrations by quantitation of the first hydrolysis product, phenylalanine, after a short period of treatment.
Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density.
Hallberg et al., Uppsala, Sweden. In Mol Pharmacol, Feb 2016
UNASSIGNED: Angiotensin IV (Ang IV) and related peptide analogues, as well as non-peptide inhibitors of insulin-regulated aminopeptidase (IRAP), have previously been shown to enhance memory and cognition in animal models.
Aminopeptidase N (APN/CD13) as a target molecule for scirrhous gastric cancer.
Kajiyama et al., Tokyo, Japan. In Clin Res Hepatol Gastroenterol, Feb 2016
In contrast, CD13(-high) subpopulation of HSC-58 was more sensitive to an aminopeptidase N inhibitor bestatin.
Antibiotic Susceptibility Evaluation of Group A Streptococcus Isolated from Children with Pharyngitis: A Study from Iran.
Tavassoli et al., Tehrān, Iran. In Infect Chemother, Dec 2015
The isolates strains from throat culture were identified as GAS by colony morphology, gram staining, beta hemolysis on blood agar, sensitivity to bacitracin, a positive pyrrolidonyl aminopeptidase (PYR) test result, and the presence of Lancefield A antigen determined by agglutination test.
TET peptidases: A family of tetrahedral complexes conserved in prokaryotes.
Franzetti et al., Grenoble, France. In Biochimie, Dec 2015
Recent studies have shed light on the assembly mechanism of homo and hetero-dodecameric TET complexes and shown that the activity of TET aminopeptidase towards polypeptides is coupled with its assembly process.
The complement of family M1 aminopeptidases of Haemonchus contortus - Biotechnological implications.
Gasser et al., Melbourne, Australia. In Biotechnol Adv, Nov 2015
Hc-AP-11 represents a leucyl/cystinyl aminopeptidase, predicted to have metallopeptidase and zinc ion binding activity, whereas Hc-AP-12 likely encodes an aminopeptidase Q homologue also with these activities and a possible role in gonad function.
Recent Developments on 1,2,4-Triazole Nucleus in Anticancer Compounds: A Review.
Kumar et al., India. In Anticancer Agents Med Chem, Sep 2015
This review article describes the role of 1,2,4-triazole nucleus in different type of anticancer agents such as nucleoside based anticancer agents, kinase inhibitors, tubulin modulators, aromatase and steroid sulfatase inhibitors, methionine aminopeptidase inhibitors, tankyrase inhibitors and metal complex based anticancer agents.
Theoretical insights into the functioning of metallopeptidases and their synthetic analogues.
Prabhakar et al., Coral Gables, United States. In Acc Chem Res, Mar 2015
In particular, the role of the metal ions, ligands, and microenvironment in the functioning of mono- and binuclear metal center containing enzymes such as insulin degrading enzyme (IDE) and bovine lens leucine aminopeptidase (BILAP), respectively, and their synthetic analogues have been investigated.
Assessment of spinal pain.
Kiltz et al., Herne, Germany. In Best Pract Res Clin Rheumatol, 2014
HLA B27 has the strongest contribution to the total genetic burden, but other major contributors such as endoplasmic reticulum aminopeptidase (ERAP)-1 and interleukin (IL)-23R have also been identified.
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.
Brown et al., Brisbane, Australia. In Nat Genet, 2013
Protective variants at two of these loci are associated both with reduced aminopeptidase function and with MHC class I cell surface expression.
Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study.
Kantarjian et al., Houston, United States. In Lancet Oncol, 2013
BACKGROUND: Tosedostat is a novel oral aminopeptidase inhibitor with clinical activity in a previous phase 1-2 study in elderly patients with relapsed or refractory acute myeloid leukaemia (AML).
Specifying and sustaining pigmentation patterns in domestic and wild cats.
Menotti-Raymond et al., Huntsville, United States. In Science, 2012
We identified the gene responsible for tabby pattern variation in domestic cats as Transmembrane aminopeptidase Q (Taqpep), which encodes a membrane-bound metalloprotease.
Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum.
Shastri et al., Berkeley, United States. In Nat Immunol, 2012
The aminopeptidase ERAAP is essential for trimming peptides presented by major histocompatibility complex (MHC) class I molecules.
Potential Use of Calpain Inhibitors as Brain Injury Therapy
Anagli et al., Boca Raton, United States. In Unknown Journal, 0001
We saw the development of a serine aminopeptidase inhibitor, vildagliptin, as a therapy for type 2 diabetes (Deacon and Holst, 2006), and another ACE inhibitor (Aliskiren) that is an alternative to the current ACE inhibitor drugs (Stanton, 2003).
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