The vagus nerve and the nicotinic anti-inflammatory pathway.
North Bay Shore, United States. In Nat Rev Drug Discov, 2005
Recent studies indicate that the vagus nerve (which is the longest of the cranial nerves and innervates most of the peripheral organs) can modulate the immune response and control inflammation through a 'nicotinic anti-inflammatory pathway' dependent on the alpha7-nicotinic acetylcholine receptor (alpha7nAChR).
Evidence for ectopic neurotransmission at a neuronal synapse.
Los Angeles, United States. In Science, 2005
At cholinergic synapses in the chick ciliary ganglion, however, membrane formations and physiological measurements suggest that release distant from postsynaptic densities can activate the predominantly extrasynaptic alpha7 nicotinic receptor subtype.