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Armadillo repeat containing, X-linked 2

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX1 and ALEX3, on the X chromosome. Two alternative transcripts that encode the same protein but differ in the 5' UTR have been described. Additional alternative transcripts may exist but their full length natures have not been determined. A pseudogene for this locus is located on chromosome 7. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, Tec, iMpact, Armadillo, ALEX3
Papers on ALEX2
Intraspecific facilitation by allelochemical mediated grazing protection within a toxigenic dinoflagellate population.
Van de Waal et al., Bremerhaven, Germany. In Proc Biol Sci, Feb 2015
Here we investigate the impact of grazing on monoclonal and mixed set-ups of highly (Alex2) and moderately (Alex4) allelochemically active A. fundyense strains and a non-allelochemically active conspecific (Alex5) by the heterotrophic dinoflagellate Polykrikos kofoidii.
Impact of elevated pCO₂ on paralytic shellfish poisoning toxin content and composition in Alexandrium tamarense.
Rost et al., Wageningen, Netherlands. In Toxicon, 2014
Here we investigated the impact of elevated pCO₂ on paralytic shellfish poisoning toxin (PST) content and composition in two strains of Alexandrium tamarense, Alex5 and Alex2.
Profiling the fatty acids from a strain of the microalgae Alexandrium tamarense by means of high-speed counter-current chromatography and gas chromatography coupled with mass spectrometry.
Vetter et al., Stuttgart, Germany. In J Chromatogr A, 2013
For this reason, we cultivated a well-defined strain of A. tamarense (Alex2, group I, North American clade) in order to study both its major and minor fatty acids.
Temporal and spatial expression profile of the novel armadillo-related gene, Alex2, during testicular differentiation in the mouse embryo.
Sinclair et al., Melbourne, Australia. In Dev Dyn, 2005
has a role in specification or development of the interstitial cell lineage in the developing testis
ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.
Nomura et al., Ibaraki, Japan. In Biochem Biophys Res Commun, 2001
ALEX1 shares significant homology with uncharacterized ORF KIAA0512 and putative protein product of unknown mRNA (GenBank AF211175), designated here as ALEX2 and ALEX3, respectively.
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