gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

ARF1 ADP-ribosylation factor 2

ADP-ribosylation factor, ADP-RIBOSYLATION FACTOR 1, ARF1-like protein U5
Gene encoding ADP-ribosylation factor and similar to other ARFs and ARF-like proteins. A member of ARF GTPase family. Arabidopsis has 21 known members, known to be essential for vesicle coating and uncoating and functions in GTP-binding. The gene is shown to play a role in cell division, cell expansion and cellulose production using antisense construct. (from NCBI)
Top mentioned proteins: p16, ARF1, ARF6, CAN, ACID
Papers on ADP-ribosylation factor
Small GTPases in peroxisome dynamics.
Peränen et al., Heidelberg, Germany. In Biochim Biophys Acta, Feb 2016
The small GTPase ADP-ribosylation factor 1 (Arf1), for example, is known to stimulate synthesis of PI4P and PI(4,5)P2 on the Golgi to regulate protein and lipid sorting.
Arf6 controls platelet spreading and clot retraction via integrin αIIbβ3 trafficking.
Whiteheart et al., Lexington, United States. In Blood, Feb 2016
ADP-ribosylation factor 6 (Arf6) is a small GTP-binding protein known to regulate endocytic trafficking, especially of integrins.
A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability.
Mila et al., Barcelona, Spain. In Eur J Hum Genet, Feb 2016
UNASSIGNED: The IQSEC2 gene is located on chromosome Xp11.22 and encodes a guanine nucleotide exchange factor for the ADP-ribosylation factor family of small GTPases.
Amino acid sensing and activation of mechanistic target of rapamycin complex 1: implications for skeletal muscle.
Koopman et al., Melbourne, Australia. In Curr Opin Clin Nutr Metab Care, Jan 2016
The mechanisms of amino acid sensing and mTORC1 signaling are emerging with multiple potential sensors (e.g., solute carrier family 38, member 9, lysosomal protein transmembrane 4 beta/solute carrier family 7, member 5-solute carrier family 3, member 2) and signal transducers (e.g., Sestrins, ADP-ribosylation factor 1, and microspherule protein 1) identified.
The Prediction of the Expected Current Selection Coefficient of Single Nucleotide Polymorphism Associated with Holstein Milk Yield, Fat and Protein Contents.
Kim et al., Seoul, South Korea. In Asian-australas J Anim Sci, Jan 2016
They are phosphodiesterase 4B (PDE4B), serine/threonine kinase 40 (STK40), collagen, type XI, alpha 1 (COL11A1), ephrin-A1 (EFNA1), netrin 4 (NTN4), neuron specific gene family member 1 (NSG1), estrogen receptor 1 (ESR1), neurexin 3 (NRXN3), spectrin, beta, non-erythrocytic 1 (SPTBN1), ADP-ribosylation factor interacting protein 1 (ARFIP1), mutL homolog 1 (MLH1), transmembrane channel-like 7 (TMC7), carboxypeptidase X, member 2 (CPXM2) and ADAM metallopeptidase domain 12 (ADAM12).
GB virus type C E2 protein inhibits human immunodeficiency virus type 1 Gag assembly by downregulating human ADP-ribosylation factor 1.
Liu et al., Nashville, United States. In Oncotarget, Jan 2016
In the present study, we identified ADP-ribosylation factor 1 (ARF1) contributed to the inhibitory effect of GBV-C E2 on HIV-1 Gag membrane targeting.
Clinical and prognostic significance of Arl4c expression in colorectal cancer.
Xu et al., In Cancer Biomark, Jan 2016
BACKGROUND: ADP-ribosylation factor (ARF)-like 4c (Arl4c) has been reported to promote tumorigenesis in colorectal and lung cancers and may represent a novel therapeutic target.
Cargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis.
Fromme et al., Ithaca, United States. In Trends Cell Biol, Jul 2015
Several different cargo adaptors functioning in distinct trafficking pathways at the Golgi are similarly regulated through bivalent binding to the ADP-ribosylation factor 1 (Arf1) GTPase, potentially enabling regulation by a threshold concentration of Arf1.
Association of the ARL15 rs6450176 SNP and serum lipid levels in the Jing and Han populations.
Pan et al., Nanning, China. In Int J Clin Exp Pathol, 2014
The association of ADP-ribosylation factor-like 15 (ARL15) rs6450176 single nucleotide polymorphism (SNP) and serum lipid profiles has never been studied in the Chinese population.
Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer.
Brown et al., Nashville, United States. In Pharmacol Rev, 2014
In mammalian cells, the pathways modulating catalytic activity involve a variety of cellular signaling components, including G protein-coupled receptors, receptor tyrosine kinases, polyphosphatidylinositol lipids, Ras/Rho/ADP-ribosylation factor GTPases, and conventional isoforms of protein kinase C, among others.
A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.
Sabatini et al., Cambridge, United States. In Nat Cell Biol, 2013
To gain more insight into the cellular mechanisms mediating BFA toxicity, we conducted a genome-wide haploid genetic screen that led to the identification of the small G protein ADP-ribosylation factor 4 (ARF4).
Molecular mechanisms of Sar/Arf GTPases in vesicular trafficking in yeast and plants.
Takeuchi et al., Tokyo, Japan. In Front Plant Sci, 2013
Two types of small GTPases, secretion-associated Ras-related protein (Sar) and ADP-ribosylation factor (Arf), act in the biogenesis of transport vesicles.
Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ.
Alto et al., Dallas, United States. In Nature, 2013
A yeast genetic screen for IpaJ substrates identified ADP-ribosylation factor (ARF)1p and ARF2p, small molecular mass GTPases that regulate cargo transport through the Golgi apparatus.
Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.
Li et al., Salt Lake City, United States. In Nature, 2013
Here we show that the direct, immediate and disruptive effects of IL-1β on endothelial stability in a human in vitro cell model are NF-κB independent and are instead the result of signalling through the small GTPase ADP-ribosylation factor 6 (ARF6) and its activator ARF nucleotide binding site opener (ARNO; also known as CYTH2).
ARF family G proteins and their regulators: roles in membrane transport, development and disease.
Jackson et al., Bethesda, United States. In Nat Rev Mol Cell Biol, 2011
Members of the ADP-ribosylation factor (ARF) family of guanine-nucleotide-binding (G) proteins, including the ARF-like (ARL) proteins and SAR1, regulate membrane traffic and organelle structure by recruiting cargo-sorting coat proteins, modulating membrane lipid composition, and interacting with regulators of other G proteins.
share on facebooktweetadd +1mail to friends