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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

ACT1 Act1p

Actin, ACT1
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, POLYMERASE, V1a
Papers using Actin antibodies
Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells
Methner Axel et al., In Journal of Neuroinflammation, 2010
... the anti-Nrf2 antibody was from Santa Cruz Biotechnology, Bergheimer Straße 89, 69115 Heidelberg, Germany; the anti-Actin antibody and secondary antibodies were from Millipore, 290 Concord Road Billerica, MA 01821, USA; the anti-NF-κB-antibody was from Cell Signaling Technologies, 3 Trask Lane Danvers, ...
Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1
Singh Lalit P. et al., In Experimental Diabetes Research, 2010
... and HMGB1 are from Santa Cruz Biotechnology (Santa Cruz, CA), and VDUP1 (TXNIP), tubulin, and Actin were from Abcam (Cambridge, MA) ...
mTORC1 signaling: what we still don’t know
Tajmir-Riahi Heidar-Ali, In PLoS ONE, 2010
... and 4E-BP-1 were obtained from Cell Signaling (New England Biolabs, Hertfordshire, UK), and antibody against β-Actin, anti-rabbit IgG-horseradish peroxidase-conjugated secondary antibody, and anti-mouse IgG-horseradish peroxidase-conjugated secondary antibody were from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
Leverkus Martin et al., In The Journal of Cell Biology, 2008
... β-Actin antibodies were purchased from Sigma-Aldrich, and HRP-coupled monoclonal antibody to GFP was purchased from Clontech.
Inhibitory effect of eupatilin and jaceosidin isolated from Artemisia princeps on carrageenan-induced inflammation in mice
Sohn Uy Dong et al., In The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2008
... phospho-SAPK/JNK, SAPK/JNK, phospho-p38 MAPK, and p38 MAPK antibodies from Cell Signaling Technology (Beverly, MA, USA); Actin antibody from Santa Cruz Biotechnology (Santa Cruz, CA, USA); ...
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Papers on Actin
Barcoding and species recognition of opportunistic pathogens in Ochroconis and Verruconis.
de Hoog et al., Utrecht, Netherlands. In Fungal Biol, Feb 2016
SSU, ITS, LSU, ACT1, BT2, and TEF1 were unable to reach all 'gold standard' criteria of barcoding markers.
Mechanical regulation of vascular network formation in engineered matrices.
Levenberg et al., Israel. In Adv Drug Deliv Rev, Feb 2016
Actin and myosin II are key molecular players in controlling initiation of vessel sprouting and branching morphogenesis.
Evaluation of the reference genes for expression analysis using quantitative Real-Time PCR in the Green peach aphid, Myzus persicae.
Liu et al., China. In Insect Sci, Feb 2016
18s, Actin and ribosomal protein L27 (L27) were recommended as the most stable reference genes for M. persicae, whereas ribosomal protein L27 (L27) were found to be the least stable reference genes for abiotic studies (photoperiod, temperature and insecticide susceptibility).
Subcutaneous Axillary and Scalp Metastases from Non-Gynecological Retroperitoneal Leiomyosarcoma: An Unusual Presentation After Surgical Resection.
Sood et al., Ludhiāna, India. In Rare Tumors, Jan 2016
Fine needle aspiration cytology from both these sites revealed a sarcoma, which was positive for Smooth Muscle Actin and negative for S100 on cell block immuno-histochemistry (IHC).
Development and Application of a High Throughput Protein Unfolding Kinetic Assay.
Stollar et al., Madison, United States. In Plos One, Dec 2015
Here, we present a simple high throughput protein unfolding kinetic assay using a plate reader that is applicable to the studies of the majority of 2-state folding proteins.
Proteomics-Based Identification and Analysis of Proteins Associated with Helicobacter pylori in Gastric Cancer.
Guan et al., Guiyang, China. In Plos One, Dec 2015
pylori) is a spiral-shaped Gram-negative bacterium that causes the most common chronic infection in the human stomach.
ACTIN-DIRECTED TOXIN. ACD toxin-produced actin oligomers poison formin-controlled actin polymerization.
Kudryashov et al., Columbus, United States. In Science, Aug 2015
Actin cross-linking by ACD is thought to lead to slow cytoskeleton failure owing to a gradual sequestration of actin in the form of nonfunctional oligomers.
Turoverov et al., In Tsitologiia, 2014
It is shown that the native globular actin (G-actin) is the thermodynamically unstable (quasi-stationary) form of the protein.
Rapid recurrence and bilateral lungs, multiple bone metastasis of malignant solitary fibrous tumor of the right occipital lobe: report of a case and review.
Ding et al., Guangzhou, China. In Diagn Pathol, 2014
The authors report a case of MSFT of the right occipital lobe with a rapid recurrence and bilateral lung, multiple bone metastasis.
The Evolving View of IL-17-Mediated Immunity in Defense Against Mucocutaneous Candidiasis in Humans.
Maródi et al., Debrecen, Hungary. In Int Rev Immunol, 2014
Inborn errors of immunity affecting IL-17+ T cell differentiation have recently been defined, such as deficiencies of signal transducer and activator of transcription (STAT)3, STAT1, IL-12Rβ1 and IL-12p40, and caspase recruitment domain 9. Impaired receptor-ligand coupling was identified in patients with IL-17F and IL-17 receptor A (IL17RA) deficiency and autoimmune polyendocrine syndrome (APS) type 1. Mutation in the nuclear factor kappa B activator (ACT) 1 was described as a cause of impaired IL-17R-mediated signaling.
RNA-Binding Proteins in Trichomonas vaginalis: Atypical Multifunctional Proteins.
Arroyo et al., Mexico. In Biomolecules, 2014
The tvcp4 and tvcp12 mRNAs have a stem-loop structure in the 5'-coding region or in the 3'-UTR, respectively that interacts with T. vaginalis multifunctional proteins HSP70, α-Actinin, and Actin under iron starvation condition, causing translation inhibition or mRNA stabilization similar to the previously characterized IRE-IRP system in eukaryotes.
Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming.
Rana et al., Los Angeles, United States. In Cell Stem Cell, 2014
Here, we report a kinome-wide RNAi-based analysis to identify kinases that regulate somatic cell reprogramming to iPSCs.
An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
Casanova et al., New York City, United States. In Immunity, 2013
We report a biallelic missense mutation (T536I) in the adaptor molecule ACT1 in two siblings with CMC.
CIKS/Act1-mediated signaling by IL-17 cytokines in context: implications for how a CIKS gene variant may predispose to psoriasis.
Siebenlist et al., Bethesda, United States. In J Immunol, 2012
A CIKS mutant may promote the initiation of psoriatic inflammation
Direct redox regulation of F-actin assembly and disassembly by Mical.
Terman et al., Dallas, United States. In Science, 2012
actin filament subunits were directly modified by Mical on their conserved pointed-end, critical for filament assembly; Mical posttranslationally oxidized the methionine 44 residue within D-loop of actin, severing filaments and decreasing polymerization
Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly.
Holak et al., Martinsried, Germany. In Proc Natl Acad Sci U S A, 2012
Data suggest that the molecular and structural mechanism of actin polymerization by Spire should apply to other actin-binding proteins that contain WH2 domains in tandem.
A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.
Li et al., Cleveland, United States. In Sci Signal, 2010
Data show that deletion of the CC' loop from Act1 or IL-17RA abolished the interaction between both proteins.
Persistent stimulation with interleukin-17 desensitizes cells through SCFβ-TrCP-mediated degradation of Act1.
Qian et al., Shanghai, China. In Sci Signal, 2010
Data indicate that knockdown of beta-TrCP1 and beta-TrCP2 markedly reduced IL-17-induced, phosphorylation-dependent ubiquitination and degradation of Act1.
Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis.
Treisman et al., London, United Kingdom. In Nat Cell Biol, 2009
Only a few genes show MRTF-dependent expression in both cell lines.
Targeted pre-mRNA modification for gene silencing and regulation.
Yu et al., Rochester, United States. In Nat Methods, 2008
We designed an artificial C/D RNA to target the branch point adenosine of ACT1 pre-mRNA to block its splicing.
More papers using Actin antibodies
Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide.
Dieli Francesco, In PLoS ONE, 2008
... of cytokine signaling 3 (SOCS3), proliferating cell nuclear antigen (PCNA), phosphoinositide 3-kinases 85α (PI3K85α), PI3K110α and Actin antibody were obtained from Santa Cruz Biotechnology, Inc ...
The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import
Kaether Christoph et al., In Cellular and Molecular Life Sciences, 2007
... ], mouse anti-importin β1 (3E9; Dianova), mouse anti-myc (9E10; Santa Cruz Biotechnology), rabbit anti-beta Actin (ab8227; Abcam), goat anti-GST (GE Healthcare) ...
Enhanced recovery from contraction-induced damage in skeletal muscles of old mice following treatment with the heat shock protein inducer 17-(allylamino)-17-demethoxygeldanamycin
Chang Jang-Yang et al., In Molecular Cancer, 2007
... The antibodies used in this study included a mouse anti-Actin antibody (Santa Cruz Biotechnology, Santa Cruz, CA), a rabbit ...
To reg or not to reg: that is the question in COPD.
Idzko Marco, In PLoS ONE, 2007
... mouse anti-human Cytokeratin 18 (Pierce), mouse anti-human E-cadherin (Dako), mouse anti-human Smooth Muscle Actin (Dako; M0851), and mouse anti-human ...
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation
Vale Ronald D. et al., In The Journal of Cell Biology, 2007
... Actin-GFP was obtained from Clontech Laboratories, Inc ...
Precancerous stem cells can serve as tumor vasculogenic progenitors.
Bridger Joanna Mary, In PLoS ONE, 2007
... Mouse anti-β-Actin (1∶1,000) and mouse anti-Tubulin (1∶2,000) antibodies were purchased from Santa Cruz Biotechnology Inc ...
p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis
Bhat Manoj K et al., In Cell & Bioscience, 2006
... mouse monoclonal), E6 (goat polyclonal and mouse monoclonal), GAPDH (goat polyclonal), β-Tubulin (rabbit polyclonal) and β-Actin (goat polyclonal) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
C-terminal modifications regulate MDM2 dissociation and nuclear export of p53.
Jin Dong-Yan, In PLoS ONE, 2006
... Other antibodies used were anti-myc (9E10), anti-FLAG (M2), anti-HA (12CA5), and β-Actin (Cell signaling technology) ...
Induced pluripotent stem cell lines derived from human somatic cells
Kasahara Noriyuki et al., In Molecular Therapy. Nucleic Acids, 2006
... β-Actin primary antibody (ab8227; Abcam, Cambridge, MA) was used ...
Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase.
Cordes Nils, In PLoS ONE, 2006
... (Abcam; and gift from Pam Silver, Dana-Farber Cancer Institute), anti-GFP mouse monoclonal antibody (Santa Cruz), anti-Actin mouse monoclonal antibody (Sigma), anti-α-Tubulin rabbit polyclonal antibody (Abcam), anti-E-cadherin antibody, anti-β-catenin antibody, ...
Prevention of mammary tumorigenesis by intermittent caloric restriction: does caloric intake during refeeding modulate the response?
Cleary Margot P et al., In Breast Cancer Research : BCR, 2006
... β-Actin was purchased from Delta Biolabs, LLC (Gilroy, CA, USA) ...
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics
Bertozzi Carolyn R. et al., In ACS Chemical Biology, 2005
... α-Actin clone C4 was obtained from AbCAM.
ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of Rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells.
Blagosklonny Mikhail V., In PLoS ONE, 2005
... Antibodies were obtained as follows: anti-p-Tyr-EGFR1173/p-Tyr1248, p-Tyr-Src 416, p-Tyr-SHP2, and β-Actin were all obtained from Cell Signaling Technology Inc (Danvers, MA) ...
Unidirectional Notch signaling depends on continuous cleavage of Delta.
Rutherford Suzannah, In PLoS ONE, 2004
... , Hunchback (gift from Paul MacDonald), Kruppel (gift from John Reinitz), Pericardin (EC11, DSHB), or Actin (Abcam, ab49846), following standard protocols ...
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
Barillé-Nion Sophie et al., In Breast Cancer Research : BCR, 2004
... Antibodies to Bax and Actin were from Dako (Trappes, France) and Millipore, ...
Prognostic impact of VEGF, CD31, CD34, and CD105 expression and tumour vessel invasion after radical surgery for IB-IIA non-small cell lung cancer
Cho Myung-Haing et al., In International Journal of Nanomedicine, 2003
... Bax, Bcl-xL, proliferating cell nuclear antigen (PCNA), Cyclin B1, vascular endothelial growth factor (VEGF), and Actin antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice.
Navarro Alfons, In PLoS ONE, 2003
... anti-CD31, anti-VEGF, anti-MMP-2, anti-MMP-9 and anti-Actin antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells.
Callaerts Patrick, In PLoS ONE, 2003
... Actin-GFP transgenic mice C57BL/6-Tg(ACTbEGFP)10sb/J were purchased ...
Equine estrogens differentially prevent cell death induced by glutamate
Bhavnani Bhagu R et al., In BMC Neuroscience, 2002
... ) and goat polyclonal antibody to Actin (sc1616) from Santa Cruz Biotechnology, Inc (Santa Cruz, Ca) ...
ErbB2/neu kinase modulates cellular p27Kip1 and cyclin D1 through multiple signaling pathways
Penichet Manuel L et al., In Breast Cancer Research : BCR, 2000
... β-Actin antibody (ab8226) was purchased from Abcam Inc ...
A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission.
Grimes H. Leighton, In PLoS Genetics, 1996
... High contribution chimeras were subsequently crossed to Actin-flpe transgenic mice ...
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
Yang Bo et al., In Journal of Biomedicine and Biotechnology, 1996
... -Actin, and HRP-labeled secondary antigoat, antimouse, and antirabbit antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation.
Cordes Nils, In PLoS ONE, 1995
... Monoclonal anti-FLNa (Chemicon), monoclonal anti-vinculin antibody (Sigma), monoclonal anti-Actin (Abcam) polyclonal anti-GFP (Rockland), polyclonal ...
Endogenous beta-galactosidase activity in the larval, pupal, and adult stages of the fruit fly, Drosophila melanogaster, indicates need for caution in lacZ fusion-gene studies
Monesi Nadia et al., In BMC Molecular Biology, 1995
... Actin), 30 μg of total RNA extracted from 3 h prepupae of the (-57/+40) transgenic line were hybridized either ...
Homology modelling of the catalytic domain of human furin: A model for the eukaryotic subtilisin-like proprotein convertases.
Antopolsky Maxim, In PLoS ONE, 1993
... The primary and secondary antibodies for PDGF-B, Actin and FLAG tag were bought from Santa Cruz Biotechnology Inc (Santa Cruz, Ca, ...
Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402
Neumann Carola A et al., In The EMBO Journal, 1992
... (110B7E) and HA-tag were purchased from Cell Signaling; Antibodies recognizing PTEN (A2B1), PTEN (N-19) and Actin (C-11) were purchased from Santa Cruz; antibodies against Prdx1 and Prdx1-SO2/-SO3 were purchased from Abcam; Ras antibody from Oncogene; ...
Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach
Ekblom Peter et al., In Journal of Negative Results in Biomedicine, 1990
... cDNA probes used: a 935 bp PCR generated GP210 probe (nt 4286–5220), a 1.8 kb human β-Actin control probe (Clontech) and a 1023 bp PCR ...
Spontaneous remission of solar keratoses: the case for conservative management.
Santos Janine, In PLoS ONE, 1985
... We used primary antibodies against Ser 1981-phosphorylated ATM (Rockland), ATM (Abcam), Lamin A (Abcam), Actin (Abcam) and Giantin Golgi marker ...
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
Mohammad Ramzi M et al., In Molecular Cancer, 1983
... Primary antibody specific for Actin was obtained from Santa Cruz Biotechnology, (Santa Cruz, CA) ...
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