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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Acetyl-CoA acetyltransferase 1

acetoacetyl-CoA thiolase
catalyzes the conversion of 2 acetyl-CoA molecules to acetoacetyl-CoA plus CoA [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, STEP, fibrillin-1
Papers on acetoacetyl-CoA thiolase
Regulation of isoprenoid pheromone biosynthesis in bumblebee males.
Pichová et al., Praha, Czech Republic. In Chembiochem, Jan 2016
RNA-seq and qRT-PCR analyses indicated that acetoacetyl-CoA thiolase (AACT), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), and farnesyl diphosphate synthase (FPPS) transcripts are abundant in the B. terrestris labial gland.
Dictyostelium acetoacetyl-CoA thiolase is a dual-localizing enzyme that localizes to peroxisomes, mitochondria and the cytosol.
Ohmachi et al., Hirosaki, Japan. In Microbiology, Jul 2015
Acetoacetyl-CoA thiolase is an enzyme that catalyses both the CoA-dependent thiolytic cleavage of acetoacetyl-CoA and the reverse condensation reaction.
Inborn errors of ketone body utilization.
Fukao et al., Gifu, Japan. In Pediatr Int, Feb 2015
Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency and mitochondrial acetoacetyl-CoA thiolase (beta-ketothiolase or T2) deficiency are classified as autosomal recessive disorders of ketone body utilization characterized by intermittent ketoacidosis.
Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation.
Stamler et al., Cleveland, United States. In Proc Natl Acad Sci U S A, 2015
Further, we report that Adh6, acting as a selective SNO-CoA reductase, protects acetoacetyl-CoA thiolase from inhibitory S-nitrosylation and thereby affects sterol biosynthesis.
Clonorchis sinensis acetoacetyl-CoA thiolase: identification and characterization of its potential role in surviving in the bile duct.
Yu et al., Guangzhou, China. In Parasit Vectors, 2014
In this study, C. sinensis acetoacetyl-CoA thiolase (CsACAT), a member of the thiolase family which has a key role in the beta oxidation pathway of fatty acid production, was identified and characterized to understand its potential role in adapting to the bile environment.
Effect of nitrogen and temperature on the transcription of an ACAT gene in Isochrysis galbana.
Sun et al., Tai'an, China. In Mol Biol Rep, 2014
Thiolases are functionally divided into two groups: 3-ketoacyl-CoA thiolase and acetoacetyl-CoA thiolase (ACAT).
Metabolic encephalopathy in beta-ketothiolase deficiency: the first report from India.
Fukao et al., Hyderābād, India. In Brain Dev, 2014
Beta-ketothiolase deficiency, or mitochondrial acetoacetyl-CoA thiolase (T2) deficiency, is a rare autosomal recessive disorder affecting isoleucine catabolism and ketone body metabolism.
First report of 3-oxothiolase deficiency in iran.
Soltani et al., Sārī, Iran. In Int J Endocrinol Metab, 2014
INTRODUCTION: Mitochondrial acetoacetyl-CoA thiolase (3-oxothiolase) deficiency is a rare metabolic disorder involving ketone body metabolism characterized by acute attacks of vomiting, acidosis, ketosis, and lethargy along with some laboratory criteria including excessive excretion of 2-methyl-3-hydroxybutyric acid in urine.
Understanding the function of bacterial and eukaryotic thiolases II by integrating evolutionary and functional approaches.
Ayub et al., Buenos Aires, Argentina. In Gene, 2014
Acetoacetyl-CoA thiolase (EC,
Development of a multi-gene expression system in Xanthophyllomyces dendrorhous.
Kondo et al., Kōbe, Japan. In Microb Cell Fact, 2013
Using this system, three mevalonate synthetic pathway genes encoding acetoacetyl-CoA thiolase, HMG-CoA synthase and HMG-CoA reductase were overexpressed at the same time.
Development of MLPA for human ACAT1 gene and identification of a heterozygous Alu-mediated deletion of exons 3 and 4 in a patient with mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.
Kondo et al., Gifu, Japan. In Mol Genet Metab, 2013
Mitochondrial acetoacetyl-CoA thiolase deficiency is an autosomal recessive disorder, characterized by intermittent ketoacidosis.
Three Japanese Patients with Beta-Ketothiolase Deficiency Who Share a Mutation, c.431A>C (H144P) in ACAT1 : Subtle Abnormality in Urinary Organic Acid Analysis and Blood Acylcarnitine Analysis Using Tandem Mass Spectrometry.
Kondo et al., Gifu, Japan. In Jimd Rep, 2011
Mitochondrial acetoacetyl-CoA thiolase (T2) deficiency affects both isoleucine catabolism and ketone body metabolism.
Enzymes of the mevalonate pathway of isoprenoid biosynthesis.
Miziorko, Kansas City, United States. In Arch Biochem Biophys, 2011
The biosynthetic acetoacetyl-CoA thiolase and HMG-CoA synthase reactions rely on key amino acids that are different but are situated in active sites that are similar throughout the family of initial condensation enzymes.
Inborn errors of isoleucine degradation: a review.
Korman, Jerusalem, Israel. In Mol Genet Metab, 2006
Deficiency of beta-ketothiolase (beta-KT, also known as T2, mitochondrial acetoacetyl-CoA thiolase and acetyl-CoA acetyltransferase 1) is a well-described disorder which presents with acute episodic ketoacidosis.
Peroxisomal protein targeting and identification of peroxisomal targeting signals in cholesterol biosynthetic enzymes.
Krisans et al., San Diego, United States. In Biochim Biophys Acta, 2001
Peroxisomes have been shown to contain acetoacetyl-CoA thiolase, HMG-CoA synthase, HMG-CoA reductase, mevalonate kinase, phosphomevalonate kinase, phosphomevalonate decarboxylase, isopentenyl diphosphate isomerase and FPP synthase.
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