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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Adenosine A2b receptor

Top mentioned proteins: A2A, V1a, CAN, HAD, ACID
Papers on A2B
Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction.
Jackson et al., Bhutan. In J Pharmacol Exp Ther, Feb 2016
Here, we test the hypothesis that combined A1/A2B adenosine receptor blockade is beneficial in obese ZSF1 rats, an animal model of HFpEF with metabolic syndrome.
Intramolecular electron transfer reactions in meso-(4-nitrophenyl)-substituted subporphyrins.
Osuka et al., Kyoto, Japan. In Chem Commun (camb), Feb 2016
A2B-type meso-(4-nitrophenyl)-substituted subporphyrins have been synthesized and shown to undergo very fast photoinduced intramolecular charge separation (CS) and charge recombination (CR) between the subporphyrin core and the meso-4-nitrophenyl group in CH2Cl2 as probed by femtosecond time-resolved transient absorption spectroscopy.
Mesenchymal Stem Cells Ageing: Targeting the "Purinome" to Promote Osteogenic Differentiation and Bone Repair.
Correia-de-Sá et al., Porto, Portugal. In J Cell Physiol, Feb 2016
Nucleotides and their derivatives act via adenosine P1 (A1 , A2A , A2B and A3 ) and nucleotide-sensitive P2 purinoceptors comprising ionotropic P2X and G-protein-coupled P2Y receptors.
Remifentanil-induced preconditioning has cross-talk with A1 and A2B adenosine receptors in ischemic-reperfused rat heart.
Park et al., Spain. In Bosn J Basic Med Sci, Feb 2016
These increases in the R-Pre group were blocked by naloxone, a nonspecific ADR antagonist, an A1 ADR antagonist, and an A2B ADR antagonist.
Up regulation of A2B adenosine receptor on monocytes are crucially required for immune pathogenicity in Indian patients exposed to Leishmania donovani.
Bimal et al., Patna, India. In Cytokine, Jan 2016
Here, we investigated the relationship between Leishmania donovani infection and expression of A2B receptor on monocytes in VL patients in their pre and post treatment stage.
A2B adenosine receptor activation switches differentiation of bone marrow cells to a CD11c(+)Gr-1(+) dendritic cell subset that promotes the Th17 response.
Sun et al., Los Angeles, United States. In Immun Inflamm Dis, Dec 2015
The non-selective AR agonist NECA and an A2BR-specific agonist had a similar effect, and the effect of NECA could be blocked by an A2BR-specific antagonist.
Purinergic signalling in brain ischemia.
Pugliese et al., Florence, Italy. In Neuropharmacology, Dec 2015
Evidence up to now in literature indicate that A2A receptor antagonists provide protection centrally by reducing excitotoxicity, while agonists at A2A (and possibly also A2B) and A3 receptors provide protection by controlling massive infiltration and neuroinflammation in the hours and days after brain ischemia.
Adenosine receptor targets for pain.
Sawynok, Halifax, Canada. In Neuroscience, Nov 2015
A2BR agonists exhibit peripheral proinflammatory effects on immune cells, but also spinal antinociceptive effects similar to A2AR agonists.
Adenosine receptors and diabetes: Focus on the A(2B) adenosine receptor subtype.
Gessi et al., Ferrara, Italy. In Pharmacol Res, Sep 2015
The nucleoside adenosine has long been known to affect insulin secretion, glucose homeostasis and lipid metabolism, through activation of four G protein coupled adenosine receptors (ARs), named A1, A2A, A2B and A3.
Adenosine Signaling Mediates Osteogenic Differentiation of Human Embryonic Stem Cells on Mineralized Matrices.
Varghese et al., San Diego, United States. In Front Bioeng Biotechnol, 2014
Here, we show that CaP matrix-driven osteogenic differentiation of hESCs occurs through A2b adenosine receptor (A2bR).
Current status of A1 adenosine receptor allosteric enhancers.
Varani et al., Ferrara, Italy. In Future Med Chem, 2014
Adenosine is an ubiquitous nucleoside involved in various physiological and pathological functions by stimulating A1, A2A, A2B and A3 adenosine receptors (ARs).
The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives.
Spalluto et al., Trieste, Italy. In Plos One, 2014
In particular, the PTP scaffold was conjugated at the C2 position with the 1-(3-trifluoromethyl-benzyl)-1H-pyrazole, a group believed to confer potency and selectivity toward the human (h) A2B adenosine receptor (AR) to the xanthine ligand 8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione (CVT 6975).
Adenosine receptor A2b on hematopoietic cells mediates LPS-induced migration of PMNs into the lung interstitium.
Reutershan et al., Tübingen, Germany. In Am J Physiol Lung Cell Mol Physiol, 2012
Distinct roles for hematopoietic cell A(2b) receptor in cell trafficking and for endothelial A(2b) receptor for microvascular permeability.
A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo.
Ravid et al., Boston, United States. In J Biol Chem, 2012
Study identified the A2BAR as a new regulator of osteoblast differentiation, bone formation, and fracture repair.
Leishmania amazonensis impairs DC function by inhibiting CD40 expression via A2B adenosine receptor activation.
Afonso et al., Ouro Preto, Brazil. In Eur J Immunol, 2012
It is proposed that A2B adenosine receptor activation may be used by L. amazonensis to inhibit dendritic cell function and evade the immune response.
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.
Eltzschig et al., Aurora, United States. In Nat Med, 2012
studies identify adenosine-elicited stabilization of Per2 in the control of HIF-dependent cardiac metabolism and ischemia tolerance and implicate Per2 stabilization
A2BR adenosine receptor modulates sweet taste in circumvallate taste buds.
Finger et al., Aurora, United States. In Plos One, 2011
This studiy identified a novel regulator of sweet taste, the A2BR, which functions to potentiate sweet responses in posterior lingual taste fields.
Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
Eltzschig et al., Tübingen, Germany. In Nat Immunol, 2009
Neutrophil transepithelial migration studies showed that by engaging A2B adenosine receptor (A2BAR) on neutrophils, netrin-1 attenuated neutrophil transmigration.
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases.
Pacher et al., Newark, United States. In Nat Rev Drug Discov, 2008
Adenosine is a key endogenous molecule that regulates tissue function by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3.
Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation.
Tessier-Lavigne et al., San Francisco, United States. In Science, 2001
Activation of the adenosine A2B receptor, proposed to contribute to netrin effects on axons, is not required for rat commissural axon outgrowth or Xenopus spinal axon attraction to netrin-1.
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