Moonlighting functions of the NRZ (mammalian Dsl1) complex.
Hachiōji, Japan. In Front Cell Dev Biol, 2013
Its metazoan counterpart NRZ complex, which comprises NAG, RINT1, and ZW10, is also involved in Golgi-to-ER retrograde transport, but each component of the complex has diverse cellular functions including endosome-to-Golgi transport, cytokinesis, cell cycle checkpoint, autophagy, and mRNA decay.
Regulators of the cytoplasmic dynein motor.
Cambridge, United States. In Nat Rev Mol Cell Biol, 2009
The answer could lie in the several multifunctional adaptors, including dynactin, lissencephaly 1, nuclear distribution protein E (NUDE) and NUDE-like, Bicaudal D, Rod-ZW10-Zwilch and Spindly, that regulate dynein function and localization.