Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats.
Uppsala, Sweden. In Acta Physiol (oxf), 2014
The expression levels of the tight junction components, zona occludens (ZO)-1, ZO-2, and ZO-3, claudin-2, claudin-3, claudin-4, occludin, and myosin light chain kinase and of the melatonin receptors MT1 and MT2 were assessed using qRT-PCR.
Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2.
Salzburg, Austria. In Tissue Barriers, 2013
Zonula occludens proteins (ZO-1, ZO-2, ZO-3), which belong to the family of membrane-associated guanylate kinase (MAGUK) homologs, serve as molecular hubs for the assembly of multi-protein networks at the cytoplasmic surface of intercellular contacts in epithelial and endothelial cells.
ZO proteins and redox-dependent processes.
Mexico. In Antioxid Redox Signal, 2011
SIGNIFICANCE: ZO-1, ZO-2, and ZO-3 are scaffold proteins of the tight junction (TJ) that belong to the MAGUK protein family characterized for exhibiting PDZ, SH3, and GuK domains.