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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Solute carrier family 30

ZnT6, hZnT-6
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008] (from NCBI)
Papers on ZnT6
Zinc transporter mRNA levels in Alzheimer's disease postmortem brain.
Johnston et al., Ireland. In J Alzheimers Dis, 2011
The results of this study showed that signi fi cant positive correlations between ZIP1,ZnT1, and ZnT6 in most brain in patient with Alzheimer's disease.
Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain.
Lovell et al., Lexington, United States. In Brain Pathol, 2010
our results suggest that alterations in Zn transport proteins ZnT-1, ZnT-4 and ZnT-6 may contribute to the pathology observed in preclinical Alzheimer's disease subjects before onset of clinical symptoms
Demonstration and characterization of the heterodimerization of ZnT5 and ZnT6 in the early secretory pathway.
Kambe et al., Kyoto, Japan. In J Biol Chem, 2009
The cytosolic C-terminal tail of ZnT5 is important for its interaction with ZnT6 as a heterodimer.
Abundant expression of zinc transporters in the amyloid plaques of Alzheimer's disease brain.
Wang et al., Shenyang, China. In Brain Res Bull, 2008
Data show that ZNT6 is extensively present in the Abeta-positive plaques in the cortex of human AD brains.
Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9.
Rink et al., Aachen, Germany. In J Leukoc Biol, 2008
hZnT-6 is up-regulated in response to cellular zinc depletion in Raji & THP-1 cells.
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