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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Zinc finger with KRAB and SCAN domains 3

Top mentioned proteins: TFEB, SET, pRb, Histone, PC1
Papers on ZNF306
Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy.
Lieberman et al., In Hum Mol Genet, 2014
Here, we confirm that autophagy is induced in cellular and knock-in mouse models of SBMA and show that the transcription factors transcription factor EB (TFEB) and ZKSCAN3 operate in opposing roles to underlie these changes.
The return of the nucleus: transcriptional and epigenetic control of autophagy.
Joseph et al., Stockholm, Sweden. In Nat Rev Mol Cell Biol, 2014
The identification of tightly controlled transcription factors (such as TFEB and ZKSCAN3), microRNAs and histone marks (especially acetylated Lys16 of histone 4 (H4K16ac) and dimethylated H3K9 (H3K9me2)) associated with the autophagic process offers an attractive conceptual framework to understand the short-term transcriptional response and potential long-term responses to autophagy.
ZKSCAN3 is a master transcriptional repressor of autophagy.
Boyd et al., Houston, United States. In Mol Cell, 2013
Herein, we establish ZKSCAN3, a zinc finger family DNA-binding protein, as a transcriptional repressor of autophagy.
Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides.
Stewart et al., Scottsdale, United States. In Blood, 2012
Five newly acquired SNVs, including truncating mutations of RB1 and ZKSCAN3, were observed only in the final sPCL sample suggesting leukemic transformation events.
The zinc finger transcription factor ZKSCAN3 promotes prostate cancer cell migration.
Yang et al., Suzhou, China. In Int J Biochem Cell Biol, 2012
In our previous studies, ZKSCAN3 was demonstrated to be over-expressed in invasive colonic tumor cells and their liver metastases, but minimally expressed in adjacent non-transformed tissues.
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Tobin et al., Leicester, United Kingdom. In Nat Genet, 2011
We identified new regions showing association (combined P < 5 × 10(-8)) with pulmonary function in or near MFAP2, TGFB2, HDAC4, RARB, MECOM (also known as EVI1), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1 and KCNE2.
Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma.
Orlowski et al., Suzhou, China. In Oncogene, 2011
ZKSCAN3 induction represents a mechanism by which myeloma cells can induce cyclin D2 dysregulation and contribute to disease pathogenesis.
Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets.
Boyd et al., Houston, United States. In J Biol Chem, 2009
ZKSCAN3 regulates the expression of several genes favoring tumor progression including integrin beta 4 and VEGF
The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression.
Boyd et al., Houston, United States. In Cancer Res, 2008
ZKSCAN3 adds to an expanding set of encoded products contributing to the progression of colorectal cancer
Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library.
Ma et al., Beijing, China. In Life Sci, 2007
Among them, five genes, TRAF3IP3, ZNF306, ZNF250, SGOL1, and ZNF434, were determined through morphological observation, calcein AM fluorescence stain, MTT assay and cell cycle analysis to be associated with cell proliferation.
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