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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Zinc finger protein 217

ZNF217, zinc finger protein 217
Top mentioned proteins: c-Myc, erbB-2, CAN, HAD, p16
Papers on ZNF217
The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value.
Review
New
Vendrell et al., Lyon, France. In Oncotarget, Jan 2016
The recently described oncogene ZNF217 belongs to a chromosomal region that is frequently amplified in human cancers.
Coordination of m(6)A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming.
New
Impact
Walsh et al., New York City, United States. In Cell Stem Cell, Jan 2016
Here we show that the chromatin-associated zinc finger protein 217 (ZFP217) coordinates epigenetic and epitranscriptomic regulation.
Aneusomy detected by fluorescence in-situ hybridization has high positive predictive value for Barrett's dysplasia.
New
Going et al., Glasgow, United Kingdom. In Histopathology, Oct 2015
(ZNF217) in 20 cases of Barrett's oesophagus.
Detection of novel germline mutations for breast cancer in non-BRCA1/2 families.
New
Bracken et al., Dublin, Ireland. In Febs J, Sep 2015
These included novel potential pathogenic mutations in MAP3K1, CASP8, RAD51B, ZNF217, CDKN2B-AS1, and ERBB2, including a splice site mutation, which we predict would generate a constitutively active HER2 protein.
DNA methylation as a promising landscape: A simple blood test for breast cancer prediction.
Review
New
Tavakkoly Bazzaz et al., Tehrān, Iran. In Tumour Biol, Jul 2015
WBC's DNA was the focus of several case-control studies at both genome wide and candidate gene levels to reveal epigenetic changes accounting for predisposition to breast cancer, leading to suggest that ATM, TITF1, SFRP1, NUP155, NEUROD1, ZNF217, DBC2, DOK7 and ESR1 genes and the LINE1, Alu and Sat2 DNA elements could be considered as the potential epimarkers.
[Lentivirus-mediated shRNA targeting ZNF217 suppresses cell growth, migration, and invasion of glioma cells in vitro].
New
Li et al., Bose, China. In Nan Fang Yi Ke Da Xue Xue Bao, Jul 2015
OBJECTIVE: To explore the role of ZNF217 in regulating cell proliferation, migration and invasion in glioma cells.
Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy.
New
Thiery et al., Singapore, Singapore. In Oncotarget, Jul 2015
The Small cell fraction also showed copy number increases in six target genes (FGFR1, Myc, CCND1, HER2, TOP2A and ZNF217) associated with breast cancer.
Fluorescence in situ hybridization identifies high risk Barrett's patients likely to develop esophageal adenocarcinoma.
New
Wang et al., Rochester, United States. In Dis Esophagus, Jul 2015
Brushing specimens were assessed by FISH probes targeting 8q24 (MYC), 9p21 (CDKN2A), 17q12 (ERBB2), and 20q13 (ZNF217) and evaluated for the presence of polysomy, defined as multiple chromosomal gains (displaying ≥ 3 signals for ≥ 2 probes).
Functional genomics of PCOS: from GWAS to molecular mechanisms.
Review
New
Strauss et al., Penn Hills, United States. In Trends Endocrinol Metab, Mar 2015
Genome-wide association studies (GWAS) identified several PCOS candidate loci including LHCGR, FSHR, ZNF217, YAP1, INSR, RAB5B, and C9orf3.
Effect of ZNF217 gene polymorphisms on colorectal cancer development in a Mexican population.
Ayala-Madrigal et al., Guadalajara, Mexico. In Genet Mol Res, 2014
The ZNF217 gene, a potential oncogene amplified and overexpressed in several cancers including colorectal cancer (CRC), acts as a transcription factor that activates or represses target genes.
Potential targets for ovarian clear cell carcinoma: a review of updates and future perspectives.
Review
Kimura et al., Suita, Japan. In Cancer Cell Int, 2014
In particular, we focus on the mechanism of platinum resistance in clear cell carcinoma, including the role of annexin A4, one of the most investigated factors of platinum resistance, as well as the mutant genes and overexpressed proteins such as VEGF, PI3K/AKT/mTOR signaling pathway, ARID1A, hepatocyte nuclear factor-1β, ZNF217.
ZNF217 is overexpressed and enhances cell migration and invasion in colorectal carcinoma.
Yang et al., Beijing, China. In Asian Pac J Cancer Prev, 2014
BACKGROUND: To investigate the expression and clinical significance of zinc finger protein 217 (ZNF217) in human colorectal carcinoma (CRC).
Gene amplification of ZNF217 located at chr20q13.2 is associated with lymph node metastasis in ovarian clear cell carcinoma.
GeneRIF
Miyazaki et al., Japan. In Anticancer Res, 2012
found ZNF217 gene amplification to be significantly correlated with lymph node metastasis (p<0.05) in ovarian clear cell carcinoma. Profound inhibition of cell migration and invasion was observed in siRNA-treated cells with ZNF217 amplification
ZNF217 is a marker of poor prognosis in breast cancer that drives epithelial-mesenchymal transition and invasion.
GeneRIF
Cohen et al., Lyon, France. In Cancer Res, 2012
study showed that high levels of expression of ZNF217 mRNA are associated with poor prognosis and the development of metastases in breast cancer; ZNF217 also promoted epithelial-mesenchymal transition (EMT) in mammary epithelial cells
Prognostic and therapeutic impact of the chromosome 20q13.2 ZNF217 locus amplification in ovarian clear cell carcinoma.
GeneRIF
Miyazaki et al., Izumo, Japan. In Cancer, 2012
These findings indicate that ZNF217 overexpression is critical to growth and survival of OCCCs with ZNF217 gene amplification.
The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain.
GeneRIF
Crossley et al., Sydney, Australia. In J Biol Chem, 2011
multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain
Overexpression of ZNF217 in glioblastoma contributes to the maintenance of glioma stem cells regulated by hypoxia-inducible factors.
GeneRIF
Huo et al., Xi'an, China. In Lab Invest, 2011
ZNF217 is overexpressed in GBMs and contributes to the maintenance of GSCs, which is regulated by HIFs released by the hypoxic environment of the tumor
Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad.
Review
GeneRIF
Crossley et al., Sydney, Australia. In Biochim Biophys Acta, 2007
ZNF217 and its associated pathways may provide new targets for therapeutic intervention in human cancers.[REVIEW]
In situ analyses of genome instability in breast cancer.
Impact
Lockett et al., San Francisco, United States. In Nat Genet, 2004
We modeled this process in vitro by measuring these same features in human mammary epithelial cell cultures during ZNF217-mediated transition through telomere crisis and immortalization.
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene.
Impact
Pinkel et al., San Francisco, United States. In Nat Genet, 2000
The putative oncogene ZNF217 (ref.
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