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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Zinc finger with KRAB and SCAN domains 1

zinc finger protein 36, ZNF139
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010] (from NCBI)
Top mentioned proteins: tristetraprolin, fibrillin-1, Insulin, CAN, Interleukin-6
Papers on zinc finger protein 36
Negative Feed-forward Control of Tumor Necrosis Factor (TNF) by Tristetraprolin (ZFP36) Is Limited by the Mitogen-activated Protein Kinase Phosphatase, Dual-specificity Phosphatase 1 (DUSP1): IMPLICATIONS FOR REGULATION BY GLUCOCORTICOIDS.
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Newton et al., Calgary, Canada. In J Biol Chem, Feb 2016
The 3'-untranslated region of the TNF transcript contains AU-rich elements (AREs) that are targeted by the RNA-binding protein, tristetraprolin (also known as zinc finger protein 36 (ZFP36)), which is itself up-regulated by inflammatory stimuli, to promote mRNA degradation.
Role of RNA-interference-induced zinc finger protein 139 suppression in gastric cancer cell sensitivity to chemotherapeutic agents.
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Wang et al., Shijiazhuang, China. In Oncol Lett, Sep 2015
ZNF139 was found to be associated with GC in our previous experiments.
[Screening and identification of proteins related to gastric cancer metastasis with comparative proteomics].
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Liu et al., Shijiazhuang, China. In Nan Fang Yi Ke Da Xue Xue Bao, Mar 2015
METHODS: Zinc finger protein 139 (ZNF139)-specific siRNA was synthesized and transfected into gastric cancer cell line SGC7901, which was then screened by G418.
Zinc finger protein 139 expression in gastric cancer and its clinical significance.
Wang et al., Shijiazhuang, China. In World J Gastroenterol, 2015
AIM: To investigate the expression of zinc finger protein 139 (ZNF139) in gastric cancer (GC), and to analyze its clinical significance.
The Expression of Tristetraprolin and Its Relationship with Urinary Proteins in Patients with Diabetic Nephropathy.
Liu et al., Zhengzhou, China. In Plos One, 2014
OBJECTIVE: Tristetraprolin (TTP), also known as zinc finger protein 36, is an RNA binding protein that has a significant role in regulating the expression of mRNAs containing AU-rich elements.
Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea.
Zhang et al., Ürümqi, China. In Genet Mol Res, 2014
Zinc finger protein 36 (ZFP36) regulates TNF-α mRNAs.
Silencing of ZNF139-siRNA induces apoptosis in human gastric cancer cell line BGC823.
Zhang et al., Shijiazhuang, China. In Int J Clin Exp Pathol, 2014
BACKGROUND AND PURPOSE: ZNF139, a member of zinc finger protein family, is a transcription factor.
Comparative proteomics in gastric cancer cell line BGC823 after ZNF139 gene inhibited with RNA interference.
Wang et al., In Hepatogastroenterology, 2014
BACKGROUND/AIMS: Zinc finger protein 139 (ZNF139) gene is proved play an important role in gastric cancer.
Association of BTG2, CYR61, ZFP36, and SCD gene polymorphisms with Graves' disease and ophthalmopathy.
Lantz et al., Malmö, Sweden. In Thyroid, 2014
RESULTS: Ten SNPs in four genes (BTG family, member 2 [BTG2], cysteine-rich, angiogenic inducer 61 [CYR61], zinc finger protein 36, C3H type, homolog mouse [ZFP36], and stearoyl-coenzyme A desaturase [SCD]) showed an association with GD and/or GO.
Regulatory mechanism of ZNF139 in multi-drug resistance of gastric cancer cells.
Wang et al., Shijiazhuang, China. In Mol Biol Rep, 2014
Our previous study found increased zinc finger protein 139 (ZNF139) expression in gastric cancer (GC) cells.
[Effect and mechanisms of TET on human gastric carcinoma cell line SGC7901 and SGC7901/ADR].
Hao et al., Shijiazhuang, China. In Zhongguo Zhong Xi Yi Jie He Za Zhi, 2014
OBJECTIVE: To investigate the effect of tetrandrine (TET) on zinc finger protein 139 (ZNF139) and multidrug resistance (MDR) of human gastric carcinoma cell lines and possible mechanisms.
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
Liu et al., In Neoplasma, 2013
Zinc finger protein 139(ZNF139), a member of zinc finger protein family, is a transcription factor.
Identification of a major phosphopeptide in human tristetraprolin by phosphopeptide mapping and mass spectrometry.
Blackshear et al., Durham, United States. In Plos One, 2013
Tristetraprolin/zinc finger protein 36 (TTP/ZFP36) binds and destabilizes some pro-inflammatory cytokine mRNAs.
[Association of MK2 and ZFP36 gene polymorphisms with high density lipoprotein cholesterol in Uygur population from Hetian area of Xinjiang].
Guo et al., Ürümqi, China. In Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2013
OBJECTIVE: To assess the association of genetic polymorphisms of mitogen-activated protein kinase activated protein kinase 2 gene (MK2) and zinc finger protein 36 gene (ZFP36) with high density lipoprotein cholesterol (HDL-C) in Xinjiang Urgur population.
NR4A2 is regulated by gastrin and influences cellular responses of gastric adenocarcinoma cells.
Thommesen et al., Trondheim, Norway. In Plos One, 2012
We show that NR4A2 is a primary early transient gastrin induced gene in adenocarcinoma cell lines, and that NR4A2 expression is negatively regulated by inducible cAMP early repressor (ICER) and zinc finger protein 36, C3H1 type-like 1 (Zfp36l1), suggesting that these gastrin regulated proteins exert a negative feedback control of NR4A2 activated responses.
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