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Zinc finger protein interacting with K protein 1 homolog

ZIK1
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Top mentioned proteins: MLH1, D4S90, Methylguanine-DNA Methyltransferase, Kms, Id4
Papers on ZIK1
Transcriptome analysis of CD133-positive stem cells and prognostic value of survivin in colorectal cancer.
Kim et al., Seoul, South Korea. In Cancer Genomics Proteomics, 2014
RESULTS: We found that in CD133(+) cells, 17 genes (RNASE2, PRB2, IL4, MGC27382, CLEC4C, SALL3, GIMAP1, ISG15, LOC728875, ZIK1, ICAM2, CCDC7, CDYL2, LRRC2, ZEB1, OSTF1 and CCDC144B) were significantly up-regulated compared to CD133(-) CRC cells.
Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model.
GeneRIF
Grady et al., Seattle, United States. In Mol Carcinog, 2010
Data indicate that Zik1 and Gja9 demonstrated cancer-specific aberrant DNA methylation, whereas, Cdkn2a/p16, Igfbp3, Mgmt, Id4, and Cxcr4 were methylated in both the AOM tumors and normal colon mucosa.
Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins.
Ushijima et al., Tokyo, Japan. In Am J Pathol, 2006
By a genome-wide screening, CpG islands in the putative promoter regions of four genes (ZIK1, ZNF141, KAL1, and FGF14) were found to be specifically methylated in glands with IM, and their expression was markedly decreased.
Zik1, a transcriptional repressor that interacts with the heterogeneous nuclear ribonucleoprotein particle K protein.
Bomsztyk et al., Seattle, United States. In J Biol Chem, 1996
The deduced primary structure of one of the positive clones revealed a novel zinc finger protein, hereby denoted as Zik1.
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