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Zinc finger protein of the cerebellum 5

Zic5, OPr
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, HAD, CAN, ZIC2, V1a
Papers on Zic5
TaOPR2 encodes a 12-oxo-phytodienoic acid reductase involved in the biosynthesis of jasmonic acid in wheat (Triticum aestivum L.).
Zhao et al., Beijing, China. In Biochem Biophys Res Commun, Feb 2016
Protein evolution analysis revealed that TaOPR2 belongs to the OPRⅡ subgroup and shares a high degree of identity with other higher plant OPR proteins.
Chiral N-heterocyclic carbene/Lewis acid cooperative catalysis of the reaction of 2-aroylvinylcinnamaldehydes: a switch of the reaction pathway by Lewis acid activation.
Cheng et al., Beijing, China. In Chem Commun (camb), Jan 2016
A switch of intramolecular cyclization to intermolecular dimerization was achieved by the cooperative catalysis of chiral triazole carbene and Ti(OPr-i)4 catalysts.
Striatal opioid receptor availability is related to acute and chronic pain perception in arthritis: does opioid adaptation increase resilience to chronic pain?
Jones et al., Valparaíso, Chile. In Pain, Nov 2015
Animal models of chronic pain point to upregulation of opioid receptors (OpR) in the brain, with unknown functional significance.
Jasmonic acid involves in grape fruit ripening and resistant against Botrytis cinerea.
Qian et al., Nanjing, China. In Funct Integr Genomics, Nov 2015
Jasmonic acid positively regulated its biosynthesis pathway genes LOS, AOS, and 12-oxophytodienoate reductase (OPR) and signal pathway genes COI1 and JMT.
The Octatricopeptide Repeat Protein Raa8 Is Required for Chloroplast trans Splicing.
Kück et al., Bochum, Germany. In Eukaryot Cell, Oct 2015
Raa1 and Rat2 share a structural motif, an octatricopeptide repeat (OPR), that presumably functions as an RNA interaction module.
Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2.
Kasai et al., Japan. In Oncotarget, Oct 2015
Zinc-finger transcriptional regulators ZIC1 to ZIC5 of ZIC gene family were demonstrated to associate with GLI to increase the nuclear accumulation and transcriptional activity of GLI.
A pharmacodynamic study of the optimal P2Y12 inhibitor regimen for East Asian patients with acute coronary syndrome.
Yoon et al., Wŏnju, South Korea. In Korean J Intern Med, Sep 2015
After 2 to 4 weeks, on-treatment platelet reactivity (OPR) was assessed in terms of P2Y12 reaction units (PRUs) using the VerifyNow P2Y12 assay (Accumetrics).
Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention.
Sibbing et al., New York City, United States. In Eur Heart J, Aug 2015
We sought to determine the prognostic value of low platelet reactivity (LPR), optimal platelet reactivity (OPR), or high platelet reactivity (HPR) by applying uniform cut-off values for standardized devices.
Two Chlamydomonas OPR proteins stabilize chloroplast mRNAs encoding small subunits of photosystem II and cytochrome b6 f.
Vallon et al., Paris, France. In Plant J, Jun 2015
Here, we present the characterization of two mRNA stabilization factors of the green alga Chlamydomonas reinhardtii, which both belong to the OctotricoPeptide Repeat (OPR) family.
Transcriptional Responses Associated with Virulence and Defence in the Interaction between Heterobasidion annosum s.s. and Norway Spruce.
Elfstrand et al., Uppsala, Sweden. In Plos One, 2014
However, three genes that had not previously been reported to respond to H. annosum showed specific induction to inoculation: an oxophytodienoic acid-reductase (OPR), a beta-glucosidase and a germin-like protein (GLP2) gene.
Effect of sulodexide on vascular responses and liver mitochondrial function in diabetic rats.
Kristová et al., Bratislava, Slovakia. In Physiol Res, 2014
Oxygen consumption and phosphorylation rates ([QO(2)(S(3))], [QO(2)(S(4))] and (OPR)) and respiratory control ratio (RCR) were decreased in the mitochondria of DM rats.
Description of the smallest critical region for Dandy-Walker malformation in chromosome 13 in a girl with a cryptic deletion related to t(6;13)(q23;q32).
Sánchez et al., Barcelona, Spain. In Am J Med Genet A, 2010
the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates.
Expression of ZIC family genes in meningiomas and other brain tumors.
Yokota et al., Wako, Japan. In Bmc Cancer, 2009
ZIC1, ZIC2, and ZIC5 may have roles in meningiomas
A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation.
Grinblat et al., Madison, United States. In J Cell Sci, 2009
Zic2a and zic5 as crucial players in the genetic network linking patterned gene expression to morphogenetic changes during neurulation.
The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum.
Grinblat et al., Madison, United States. In Development, 2007
Zic2a and Zic5 have essential, cooperative roles in promoting cell proliferation in the tectum, but lack obvious patterning functions.
Arrays in rays: terminal addition in echinoderms and its correlation with gene expression.
Wray et al., San Francisco, United States. In Evol Dev, 2005
However, it has long been recognized that echinoderms have serial elements along their radii formed in accordance with the ocular plate rule (OPR).
Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.
Aruga et al., Wako, Japan. In Biochem Biophys Res Commun, 2004
Results describe the molecular properties of Zic4 and Zic5 proteins.
Cross-talk of opioid peptide receptor and beta-adrenergic receptor signalling in the heart.
Xiao et al., Melbourne, Australia. In Cardiovasc Res, 2004
Opioid peptide receptor (OPR) and beta-adrenergic receptor (beta-AR) are well-established members of G-protein-coupled receptor (GPCR) superfamily and are involved in regulating cardiac contractility, energy metabolism, myocyte survival or death.
[Molecular neuropharmacology of nociceptive transmission and opioid receptors].
Satoh, Kyoto, Japan. In Yakugaku Zasshi, 2000
Using cloned cDNA for OPRs, we demonstrated (1) the distribution of mRNAs for OPRs in the rat central nervous system, (2) coexistence of each type of mRNA for mu-, delta- and kappa-OPRs and pre-protachykinin A mRNA in the dorsal root ganglion neurons, (3) an increased expression of mu- and kappa-OPR mRNAs in the I-II layers of rat lumbar dorsal horn with an adjuvant arthritis in the hind limb, (4) the inhibitions of N- and Q-types of Ca2+ channels by mu- and kappa-OPR agonists and (5) cross-desensitization of the inhibition through a common intracellular phosphorylation-independent mechanism, (6) pharmacological characterization of "antagonist analgesics" as partial agonists at every type of OPRs, and (7) the key-structure(s) of OPRs for discriminative binding of DAMGO to mu-OPR.
[Mechanisms for the development of quinolone resistance].
Kojima, In Nihon Rinsho, 1997
Bacterial resistance to the quinolones probably results from : 1) mutations with chromosomal genes of DNA gyrase or DNA topoisomerase in E. coli and S. aureus, 2) decreased permeability of the cell envelope through OmpF, porin-forming protein, in gram-negative bacteria, and 3) activation of active efflux-mediated permeability through the cell membrane protein, either NorA in S. aureus or Opr in P. aeruginosa.
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