Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer.
Baltimore, United States. In Epigenetics, 2014
We uncovered 186 downregulated genes harboring cancer specific promoter methylation including PAX1 and PAX5 and we identified 10 key tumor suppressor genes (GABRB3, HOXC12, PARP15, SLCO4C1, CDKN2A, PAX1, PIK3AP1, HOXC6, PLCB1, and ZIC4) inactivated by both promoter methylation and/or somatic mutation.
Seroprevalence of autoantibodies against brain antigens in health and disease.
Göttingen, Germany. In Ann Neurol, 2014
All other AB were found in ≤0.1% of individuals (anti-AMPAR-1/2, AQP4, CV2, Tr/DNER, DPPX-IF1, GABAR-B1/B2, GAD67, GLRA1b, GRM1, GRM5, Hu, LGl1, recoverin, Ri, ZIC4).