GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Zinc finger and BTB domain containing 38
ZBTB38, CIBZ, CtBP-interacting BTB zinc finger protein
The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010] (from
NCBI)
Sponsored links
Top mentioned proteins:
Kaiso, CAN, V1a, p53, PrP
Papers on
ZBTB38
Associations between menarche-related genetic variants and pubertal growth in male and female adolescents.
Indianapolis, United States. In J Adolesc Health, 2015
Among the nine menarche-timing and height-related SNPs, four (in or near genes ZBTB38, LOC728666, TBX2, and CABLES) were associated with changes in weight or height in EA and AA (p ≤ .0042).
The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability.
Paris, France. In Cell Rep, 2014
The E3 ubiquitin ligase RBBP6 ubiquitinates and destabilizes the transcriptional repressor ZBTB38.
An SNP of the ZBTB38 gene is associated with idiopathic short stature in the Chinese Han population.
Shanghai, China. In Clin Endocrinol (oxf), 2013
Recently, three genome-wide association studies discovered associations between the ZBTB38 and adult height in different populations.
Characterizing short stature by insulin-like growth factor axis status and genetic associations: results from the prospective, cross-sectional, epidemiogenetic EPIGROW study.
Manchester, United Kingdom. In J Clin Endocrinol Metab, 2013
An insertion-deletion (Indel) on the IGF1 gene (P = 1.2 × 10(-5), Bonferroni-corrected; case vs control frequency: 0.04 vs 0.112), an Indel on NFKB1 (P = 1.36 × 10(-10); case vs control frequency: 0.464 vs 0.272), and 2 single-nucleotide polymorphisms on ZBTB38 (P < 2.3 × 10(-6)) were associated with SS.
Genetics of prion diseases.
Review
London, United Kingdom. In Curr Opin Genet Dev, 2013
Two recent genome wide association studies in human have identified four new loci of interest: ZBTB38-RASA2 in UK CJD cases and MTMR7 and NPAS2 in variant CJD.
ZBTB38 gene polymorphism associated with body measurement traits in native Chinese cattle breeds.
Xi'an, China. In Gene, 2013
In this study, we investigated the association between genetic polymorphisms of the zinc finger and BTB domain containing 38 gene (ZBTB38) and body measurement traits in native Chinese cattle.
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
London, United Kingdom. In Hum Mol Genet, 2012
SNPs at the ZBTB38-RASA2 locus were associated with CJD in the UK (rs295301, P = 3.13 × 10(-8); OR, 0.70) but these SNPs showed no replication evidence of association in German sCJD or in Papua New Guinea-based tests.
CtBP-interacting BTB zinc finger protein (CIBZ) promotes proliferation and G1/S transition in embryonic stem cells via Nanog.
GeneRIF
Ikoma, Japan. In J Biol Chem, 2012
CIBZ post-transcriptionally regulates the expression of Nanog.
Exome sequencing and subsequent association studies identify five amino acid-altering variants influencing human height.
Seoul, South Korea. In Hum Genet, 2012
We performed association analysis in 740 cohort individuals and identified 11 nsSNPs in 10 loci (DIS3L2, ZBTB38, FAM154A, PTCH1, TSSC4, KIF18A, GPR133, ACAN, FAM59A, and NINL) associated with adult height (P < 0.05), including five novel loci.
Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.
Nashville, United States. In Plos One, 2011
This screen identified the Zinc fingers, C2H2 and BTB domain containing (ZBTB) family members ZBTB4 and ZBTB38 as MTG16 interacting proteins.
CIBZ, a novel BTB domain-containing protein, is involved in mouse spinal cord injury via mitochondrial pathway independent of p53 gene.
GeneRIF
Wuhu, China. In Plos One, 2011
CIBZ, a novel BTB domain-containing protein, is involved in mouse spinal cord injury via mitochondrial pathway independent of p53 gene.
The methyl-CpG-binding protein CIBZ suppresses myogenic differentiation by directly inhibiting myogenin expression.
GeneRIF
Ikoma, Japan. In Cell Res, 2011
CIBZ binds to a Myog promoter-proximal region and inhibits Myog transcription in a methylation-dependent manner.
Alternative splicing of human height-related zinc finger and BTB domain-containing 38 gene through Alu exonization.
GeneRIF
Seoul, South Korea. In Biochem Genet, 2011
Alternative splicing of human height-related zinc finger and BTB domain-containing 38 gene through Alu exonization
The molecular evolution of the p120-catenin subfamily and its functional associations.
Nashville, United States. In Plos One, 2009
Kaiso family members (i.e., Kaiso, ZBTB38 and ZBTB4) are found only in vertebrates, their origin following that of the p120-like gene lineage and coinciding with the evolution of vertebrate-specific mechanisms of epigenetic gene regulation by CpG island methylation.
Many sequence variants affecting diversity of adult human height.
Impact
GeneRIF
Reykjavík, Iceland. In Nat Genet, 2008
There was strongest association with SNPs in the ZBTB38 gene and adult human height.
