Prognostic Factors for Chronic Lymphocytic Leukemia.
Tucson, United States. In Curr Hematol Malig Rep, Feb 2016
The prognostic information can be categorized into three categories: genetic abnormalities which include 17p, 11q, and immunoglobulin heavy chain variable (IGHV) abnormalities; biochemical abnormalities and cell surface markers which include serum thymidine kinase, β-2-microglobulin, CD49d, CD38, and ZAP-70 levels; and patient characteristics which include sex, age, and performance status.
Modulation of CD44 Activity by A6-Peptide.
United States. In Front Immunol, 2014
Recently, A6 has been shown to be directly cytotoxic for B-lymphocytes obtained from patients with chronic lymphocytic leukemia expressing the kinase, ZAP-70.