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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Vacuolar protein sorting 72 homolog

yl-1
Top mentioned proteins: ACID, V1a, HAD, CAN, fibrillin-1
Papers using yl-1 antibodies
Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue
Supplier
van Heyningen Veronica et al., In Developmental Biology, 1994
... and Pr260; set VIII, Pr150 and Pr151; set IX, Pr154 and Pr155 and set X, YL1 and YL2.For FISH analysis, spleens were dissected from transgenic mice, washed in PBS, ...
Papers on yl-1
Dinaciclib, a Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation of Mcl-1 and Enhances ABT-737-Mediated Cell Death in Malignant Human Glioma Cell Lines.
New
Pollack et al., Pittsburgh, United States. In J Pharmacol Exp Ther, Feb 2016
In contrast, combination of the Bcl-2/Bcl-xL inhibitors ABT-263 (4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide) or ABT-737 (4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide) with dinaciclib potentiated the apoptotic response induced by each single drug.
Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats.
New
Song et al., Taejŏn, South Korea. In Arch Pharm Res, Feb 2016
A new 11β-HSD1 inhibitor known as 2-(3-benzoyl)-4-hydroxy-1, 1-dioxo-2H-1, 2-benzothiazine-2-yl-1-phenylethanone (KR-66344) is being developed as a therapeutic agent for these metabolic diseases.
Towards the chiral metabolomics: Liquid chromatography-mass spectrometry based DL-amino acid analysis after labeling with a new chiral reagent, (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl)pyrrolidine-2-carboxylate, and the application to saliva of healthy volunteers.
New
Toyo'oka et al., Shizuoka, Japan. In Anal Chim Acta, Jun 2015
A novel triazine-type chiral derivatization reagent, i.e., (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate (DMT-(S)-Pro-OSu), was developed for the highly sensitive and selective detection of chiral amines and amino acids by UPLC-MS/MS analysis.
Synthesis, crystal structure, spectroscopic and density functional theory (DFT) study of N-[3-anthracen-9-yl-1-(4-bromo-phenyl)-allylidene]-N-benzenesulfonohydrazine.
New
Birinji et al., Jiddah, Saudi Arabia. In Spectrochim Acta A Mol Biomol Spectrosc, Jun 2015
N-[3-anthracen-9-yl-1-(4-bromo-phenyl)-allylidene]-N-benzenesulfonohydrazine has been synthesized and characterized by various spectroscopic techniques including FT-IR, UV-vis, (1)H-NMR, (13)C-NMR spectroscopy, and the structure was unequivocally confirmed by single crystal X-ray diffraction studies.
Crystal structure of ethyl 6-(2-fluoro-phen-yl)-4-hy-droxy-2-sulfanyl-idene-4-tri-fluoro-meth-yl-1,3-diazinane-5-carboxyl-ate.
New
Begum et al., Bengaluru, India. In Acta Crystallogr E Crystallogr Commun, Jun 2015
In the title compound, C14H14F4N2O3S, the central di-hydro-pyrimidine ring adopts a sofa conformation with the C atom bearing the 2-fluoro-benzene ring displaced by 0.596 (3) Å from the other five atoms.
Close Packing of Nitroxide Radicals in Stable Organic Radical Polymeric Materials.
New
Gennett et al., Golden, United States. In J Phys Chem Lett, May 2015
For the radical polymer poly(2,2,6,6-tetramethylpiperidine-4-yl-1-oxyl methacrylate), it is unclear whether the radical packing is optimal for charge transport partially because the relationship between radical packing and molecular structure is not well-understood.
Crystal structure of diethyl 3,3'-{2,2'-(1E)-[1,4-phenyl-enebis(azan-1-yl-1-yl-idene)]bis-(methan-1-yl-1-yl-idene)bis-(1H-pyrrole-2,1-di-yl)}di-propano-ate.
New
Al-Jeboori et al., Al Başrah, Iraq. In Acta Crystallogr E Crystallogr Commun, May 2015
The complete mol-ecule of the title compound, C26H30N4O4, is generated by crystallographic inversion symmetry.
Blocking of orexin receptors in the paraventricular nucleus of the thalamus has no effect on the expression of conditioned fear in rats.
Kirouac et al., Winnipeg, Canada. In Front Behav Neurosci, 2014
Infusion of 0.5 μl of the DORA N-biphenyl-2-yl-1-[(1-methyl-1H-benzimidazol-2yl) sulfanyl] acetyl-L-prolinamide at a concentration of 0.1, 1.0, and 10 nmol had no effect on the freezing produced by exposing rats to an auditory cue or the context associated with foot shock.
Kinetic studies of inverse electron demand Diels-Alder reactions (iEDDA) of norbornenes and 3,6-dipyridin-2-yl-1,2,4,5-tetrazine.
Slugovc et al., Graz, Austria. In Tetrahedron Lett, 2014
Inverse electron demand Diels-Alder additions (iEDDA) between 1,2,4,5-tetrazines and olefins have recently found widespread application as a novel 'click chemistry' scheme and as a mild technique for the modification of materials.
Nucleosome-free region dominates histone acetylation in targeting SWR1 to promoters for H2A.Z replacement.
Impact
Wu et al., Bethesda, United States. In Cell, 2013
Analysis of mutants indicates that the conserved Swc2/YL1 subunit and the adenosine triphosphatase domain of Swr1 are mainly responsible for binding to substrate.
Biological Control of Apple Ring Rot on Fruit by Bacillus amyloliquefaciens 9001.
Wang et al., Beijing, China. In Plant Pathol J, 2013
Strain 9001 showed obvious antagonistic activity to B. dothidea YL-1 when plated on potato dextrose agar.
Perampanel, a novel, non-competitive, selective AMPA receptor antagonist as adjunctive therapy for treatment-resistant partial-onset seizures.
Review
Rektor, Brno, Czech Republic. In Expert Opin Pharmacother, 2013
This article reviews preclinical and clinical data for 2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile, perampanel , a new chemical entity developed for the treatment of partial-onset seizures.
Development of perampanel in epilepsy.
Review
Laurenza et al., United States. In Acta Neurol Scand Suppl, 2012
Perampanel (2-[2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl] benzonitrile) is a potent, orally active, highly selective, non-competitive AMPA-type glutamate receptor antagonist, identified via a focused discovery program at Eisai Research Laboratories.
Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist.
Review
Hanada et al., Sacramento, United States. In Acta Neurol Scand Suppl, 2012
Perampanel [2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile; E2007] is a potent, selective, orally active non-competitive AMPA receptor antagonist developed for the treatment of epilepsy.
2-{4-[-Pyridin-4-yl-1-(2-[(18)F]fluoro-ethyl)-1H-pyrazol-3-yl]-phenoxymethyl}-quinoline
Review
Leung, Bethesda, United States. In Unknown Journal, 2011
In this chapter, 2-{4-[-pyridin-4-yl-1-(2-[(18)F]fluoro-ethyl)-1H-pyrazol-3-yl]-phenoxymethyl}-quinoline ([(18)F]JNJ4151047) was found to be a selective inhibitor of PED10A (>1,000-fold better selectivity than the other nine PDE subtypes) with an IC50 value of 0.5 nM for PDE10A (14).
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.
GeneRIF
Conaway et al., Kansas City, United States. In J Biol Chem, 2005
Results identify YL1 as a subunit of the TRRAP/TIP60 HAT complex, and also as a component of a novel mammalian multiprotein complex that includes the SNF2-related helicase SRCAP.
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