Biomarkers of progression of chronic obstructive pulmonary disease (COPD).
Brisbane, Australia. In J Thorac Dis, 30 Nov 2014
Examples of peripheral blood biological markers (biomarkers) include those associated with lung function (reduced CC-16), emphysema severity (increased adiponectin, reduced sRAGE), exacerbations and mortality [increased CRP, fibrinogen, leukocyte count, IL-6, IL-8, and tumor necrosis factor α (TNF-α)] including increased YKL-40 with mortality.
The significance of YKL-40 protein in liver fibrosis.
Hefei, China. In Inflamm Res, Apr 2014
OBJECTIVE: The aims of this review are to describe the present knowledge about YKL-40 protein, discuss its relation to liver fibrosis, and to look ahead at future perspectives of YKL-40 research.
Unveiling YKL-40, from Serum Marker to Target Therapy in Glioblastoma.
New York City, United States. In Front Oncol, Dec 2013
We review the current concept of developing YKL-40 as one of the most promising serum markers for glioblastoma, the recent advances on understanding the role of YKL-40 in gliomagenesis, and the promising evidence emerging from preclinical models on using this protein as a target for anti-glioma therapy.