Gastric cancer: epidemiologic aspects.
Barcelona, Spain. In Helicobacter, 2013
Large meta-analyses confirmed the association between IL8, IL10, TNF-b, TP53 and PSCA, while genetic variation at different genes such as XPG, PLCE1, HFE, ERCC5, EZH2, DOC2, CYP19A1, ALDH2, and CDH1 have been reported to be associated with GC risk.
Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
Los Angeles, United States. In Nature, 2009
Genetic connections to mammalian XPG (also known as ERCC5) and ERCC1 in S. pombe homologues Rad13 and Swi10 and biochemical interactions with Escherichia coli UvrA and UvrC combined with structural results reveal that ATLs sculpt alkylated DNA to create a genetic and structural intersection of base damage processing with nucleotide excision repair.
ERCC5 is a novel biomarker of ovarian cancer prognosis.
Los Angeles, United States. In J Clin Oncol, 2008
ERCC5 was identified as a candidate gene in this region because of its known function in the nucleotide excision repair pathway, the unique DNA repair pathway that removes platinum-DNA adducts.