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1: Title: T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.
Authors: Houtman, Miranda, et.al. .
Journal: Journal of autoimmunity (J Autoimmun), 2018 .
Snippet: RNA sequencing analysis of LINC01882 knockdown in Jurkat T cells, using a combination of antisense oligonucleotides and RNA interference, revealed the upregulation of the transcription factor ZEB1 and kinase MAP2K4, both involved in IL-2 regulation.
Affiliation: Rheumatology Unit, Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden. Electronic address: miranda.houtman@ki.se. Rheumatology Unit, Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden. Department of Medical Sciences, Rheumatology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Institute of Human Genetics, University of Erlangen-Nuremberg, Erlangen, Germany. .
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