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75 documents found
1: Title: Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics.
Authors: Chen, Yi-Jen, et.al. .
Journal: Oncotarget, Vol. 8 (69): 113598-113613, 2017 .
Snippet: The putative targets for miR-204-5p were Kruppel-like factor 7 (KLF7) and SRY-box 11 (SOX11).
Affiliation: Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. Division of Pulmonary and Critical Care Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. Department of Internal Medicine, E-DA Cancer Hospital, Kaohsiung, Taiwan. School of Medicine, I-Shou University, Kaohsiung, Taiwan. Department of Physical Medicine and Rehabilitation, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Division of Geriatrics and Gerontology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung, Taiwan. .
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2: Title: Inhibition of KLF7-Targeting MicroRNA 146b Promotes Sciatic Nerve Regeneration.
Authors: Li, Wen-Yuan, et.al. .
Journal: Neuroscience bulletin (Neurosci Bull), 2018 .
Snippet: A previous study has indicated that Krüppel-like factor 7 (KLF7), a transcription factor that stimulates Schwann cell (SC) proliferation and axonal regeneration after peripheral nerve injury, is a promising therapeutic transcription factor in nerve injury.
Affiliation: Department of Anatomy, Mudanjiang College of Medicine, Mudanjiang, 157011, China. The Affiliated Hongqi Hospital, Mudanjiang College of Medicine, Mudanjiang, 157011, China. Department of Pathology, Mudanjiang College of Medicine, Mudanjiang, 157011, China. Department of Pharmacy, Mudanjiang College of Medicine, Mudanjiang, 157011, China. Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. Department of Anatomy, Mudanjiang College of Medicine, Mudanjiang, 157011, China. sjkx@sohu.com. Department of Anatomy, Mudanjiang College of Medicine, Mudanjiang, 157011, China. yingwang2016@sina.com. .
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3: Title: De novo variants in KLF7 are a potential novel cause of developmental delay/intellectual disability, neuromuscular and psychiatric symptoms.
Authors: Powis, Z, et.al. .
Journal: Clinical genetics (Clin Genet), 2017 .
Snippet: Among these genes is KLF7 (Krüppel-like factor 7), which is located at 2q33.3 and has been implicated in several developmental processes.
Affiliation: Ambry Genetics, Aliso Viejo, California. Kennedy Krieger Institute, Baltimore, Maryland. University of Illinois College of Medicine at Peoria, Peoria, Illinois. Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Department of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands. Department of Genetics, Radboud University Medical Center, Nijmegen, The Netherlands. GeneDx, Gaithersburg, Maryland. .
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4: Title: Krüppel Like Factors Family Expression in Cervical Cancer Cells.
Journal: Archives of medical research (Arch Med Res), Vol. 48 (4): 314-322, 2017 .
Snippet: Despite the heterogeneous expression profile, KLF3, -5, -12, -15 and -16 transcripts were present in all cell lines, KLF4 and -10 which were not expressed in CaSki; KLF11 and 13 were not expressed by Vipa and C4-I, and KLF7 was not expressed by C4-I and Rova.
Affiliation: Laboratorio de Oncología Genómica, Unidad de Investigación Médica en Enfermedades Oncológicas, Hospital de Oncología, CMN-SXXI, Instituto Mexicano del Seguro Social, Ciudad de México, México; Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados, Ciudad de México, México. Laboratorio de Oncología Genómica, Unidad de Investigación Médica en Enfermedades Oncológicas, Hospital de Oncología, CMN-SXXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados, Ciudad de México, México. Laboratorio de Biotecnología, Universidad Autonóma de Ciudad Juárez, Chihuahua, México. Laboratorio de Inmmunología y Cáncer, Unidad de Investigación Médica en Enfermedades Oncológicas, Hospital de Oncología, CMN-SXXI, Instituto Mexicano del Seguro Social, Ciudad de México, Ciudad de México, México. Laboratorio de Oncología Experimental, Instituto Nacional de Pediatria, S.S., Ciudad de México, México. Laboratorio de Oncología Genómica, Unidad de Investigación Médica en Enfermedades Oncológicas, Hospital de Oncología, CMN-SXXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: masava89@gmail.com. .
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5: Title: Waterborne Zn influenced Zn uptake and lipid metabolism in two intestinal regions of juvenile goby Synechogobius hasta.
Authors: Ling, Shi-Cheng, et.al. .
Journal: Ecotoxicology and environmental safety (Ecotoxicol Environ Saf), Vol. 148, 2018 .
Snippet: In anterior intestine, Zn addition in the water increased Zn contents, and mRNA concentrations of ZIP4, ZIP5, ATGL, PPARα, ZNF202 and KLF7, decreased TG contents, 6PGD and G6PD activities, and mRNA contents of 6PGD, G6PD, FAS, PPARγ, ICDH and KLF4.
Affiliation: Laboratory of Nutrition Physiology and Feed Formulation, Fishery College, Huazhong Agricultural University, Wuhan 430070, China. Laboratory of Nutrition Physiology and Feed Formulation, Fishery College, Huazhong Agricultural University, Wuhan 430070, China; Collaborative Innovation Center for Efficient and Health Production of Fisheries in Hunan Province, Changde 415000, China. Electronic address: luozhi99@mail.hzau.edu.cn. Panjin Guanghe Crab Co. Ltd., Panjin 124200, China. .
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6: Title: Krüppel-Like Factor 7 is a Marker of Aggressive Gastric Cancer and Poor Prognosis.
Authors: Jiang, Zhonghua, et.al. .
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (Cell Physiol Biochem), Vol. 43 (3): 1090-1099, 2017 .
Snippet: Furthermore, we observed a strong negative correlation between KLF7 expression and 5-year overall survival and disease-free survival in GC patients (P<0.05).
Affiliation: Department of Gastroenterology, the First People's Hospital of Yancheng, Yancheng, China. Department of Digestive Endoscopy, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Department of Digestive Endoscopy, the First People's Hospital of Wujiang District, Suzhou, China. .
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7: Title: Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation.
Authors: Klein, Rachel Herndon, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), 2017 .
Snippet: Taken together, our work defines regulatory enhancers in corneal epithelial cells, highlights global gene-regulatory relationships shared among different epithelial cells, identifies a role for KLF7 as a KLF4 antagonist in corneal epithelial cell differentiation, and explains how two SNPs may contribute to corneal diseases.
Affiliation: University of California Irvine, United States. University of California Irvine, United States bogi@uci.edu. .
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8: Title: AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury.
Authors: Li, Wen-Yuan, et.al. .
Journal: Neural plasticity (Neural Plast), Vol. 2017, 2017 .
Snippet: Our findings suggest that KLF7 promotes DPSN axonal plasticity and the formation of synapses with motor neurons at the caudal spinal cord, leading to improved functional recovery and further supporting the potential of AAV-KLF7 as a therapeutic agent for spinal cord injury.
Affiliation: Department of Anatomy, Basic Medical College, China Medical University, Shenyang 110122, China. Department of Anatomy, Mudanjiang College of Medicine, Mudanjiang 157011, China. Department of Pharmacy, Mudanjiang College of Medicine, Mudanjiang 157011, China. Department of Pathology, Mudanjiang College of Medicine, Mudanjiang 157011, China. Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. .
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9: Title: MicroRNA-186-5p overexpression modulates colon cancer growth by repressing the expression of the FAM134B tumour inhibitor.
Authors: Islam, Farhadul, et.al. .
Journal: Experimental cell research (Exp Cell Res), Vol. 357 (2): 260-270, 2017 .
Snippet: Western blots and immunohistochemistry analysis were performed to examine the modulation of FAM134B, PARP9 and KLF7 proteins expression.
Affiliation: Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia; Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi 6205, Bangladesh. Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia. School of Medical Science and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia. Department of Surgery, Gold Coast Hospital, Gold Coast, Queensland, Australia. Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia. Electronic address: a.lam@griffith.edu.au. .
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10: Title: KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition.
Authors: Ding, Xiaojun, et.al. .
Journal: Oncology letters (Oncol Lett), Vol. 13 (4): 2281-2289, 2017 .
Snippet: Krüppel-like factor 7 (KLF7) is a member of the KLF family of zinc finger transcription factors, and was the first KLF cloned using complementary DNA and polymerase chain reaction (PCR) techniques with human vascular endothelial cells as a template.
Affiliation: Department of Stomatology, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, P.R. China. .
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11: Title: Acute exercise regulates adipogenic gene expression in white adipose tissue.
Authors: Shen, Y, et.al. .
Journal: Biology of sport (Biol Sport), Vol. 33 (4): 381-391, 2016 .
Snippet: In epididymal white adipose tissue (eWAT), PPARγ2 and C/EBPα expression at the mRNA level was significantly decreased with high induction of Wnt10b and KLFs (KLF2, KLF3, KLF7, KLF6, KLF9 and KLF15), whereas PPARγ2, not C/EBPα, was decreased with high induction of Wnt6 and KLFs (KLF2, KLF3, KLF7, KLF6 and KLF9) in inguinal white adipose tissue (iWAT) after acute exercise.
Affiliation: University of Science and Technology of China, Hefei 230026, China; Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. .
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12: Title: [Research progress of Krüppel-like factor 7].
Authors: Chen, Yue-Chan, et.al. .
Journal: Sheng li xue bao : [Acta physiologica Sinica] (Sheng Li Xue Bao), Vol. 68 (6): 809-815, 2016 .
Snippet: Genetics reports showed that the genetic polymorphism of KLF7 is associated with obesity, type 2 diabetes, mental development in human beings; and KLF7 methylation is associated with the development of diffuse gastric cancer (gastric adenocarcinoma).
Affiliation: Department of Basic Medicine, School of Medicine, Shihezi University, Shihezi 832000, China. Office of Scientific Research, The First Affiliated Hospital of School of Medicine, Shihezi University, Shihezi 832000, China. Department of Basic Medicine, School of Medicine, Shihezi University, Shihezi 832000, China. zzwneau@163.com. .
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13: Title: Combined chondroitinase and KLF7 expression reduce net retraction of sensory and CST axons from sites of spinal injury.
Authors: Wang, Zimei, et.al. .
Journal: Neurobiology of disease (Neurobiol Dis), Vol. 99, 2017 .
Snippet: Chondroitinase was expressed by viral transduction of cells in the spinal cord, while VP16-KLF7 was virally expressed in sensory neurons of the dorsal root ganglia or corticospinal tract (CST) neurons.
Affiliation: Department of Biomedical Sciences, Marquette University, 53201, USA. Department of Biomedical Sciences, Marquette University, 53201, USA. Electronic address: murray.blackmore@marquette.edu. .
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14: Title: Molecular genetic contributions to self-rated health.
Authors: Harris, Sarah E, et.al. .
Journal: International journal of epidemiology (Int J Epidemiol), 2016 .
Snippet: The strongest signal was on chromosome 2 (rs2360675, P = 1.77 x 10(-10)) close to KLF7 A second strong peak was identified on chromosome 6 in the major histocompatibility region (rs76380179, P = 6.15 x 10(-10)).
Affiliation: Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK. Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Edinburgh, UK. Department of Psychology. Division of Psychiatry, University of Edinburgh, Edinburgh, UK. Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia. Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK. Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK i.deary@ed.ac.uk. .
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15: Title: KLF7-transfected Schwann cell graft transplantation promotes sciatic nerve regeneration.
Authors: Wang, Ying, et.al. .
Journal: Neuroscience, Vol. 340, 2017 .
Snippet: Several beneficial effects were detected in the ANA+KLF7-SCs group including an increase in the compound action potential amplitude, sciatic function index score, enhanced expression of PKH26-labeling transplant SCs, peripheral myelin protein 0, neurofilaments, S-100, and myelinated regeneration nerve.
Affiliation: Department of Anatomy, Mudanjiang College of Medicine, Mudanjiang 157011, China. Department of Anatomy, Mudanjiang College of Medicine, Mudanjiang 157011, China. Electronic address: yingwang770224@163.com. Department of Anatomy, Ningxia Medical University, Yinchuan 750004, China. Department of Pharmacology, Mudanjiang College of Medicine, Mudanjiang 157011, China. Hand & Foot Surgery and Reparative & Reconstructive Surgery Center, Orthopaedic Hospital of the Second Hospital of Jilin University, Changchun 130041, China. Department of Pathology, Mudanjiang College of Medicine, Mudanjiang 157011, China. Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, United States. .
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16: Title: Promotion of adipogenesis by neuropeptide Y during the later stages of chicken preadipocyte differentiation.
Authors: Shipp, Steven L, et.al. .
Journal: Physiological reports (Physiol Rep), Vol. 4 (21), 2016 .
Snippet: At 12 h posttreatment, mRNA abundance of topoisomerase II alpha (TOP2A), and thioredoxin-dependent peroxidase 2 was upregulated and NPY was downregulated in response to NPY (0 vs. 100 nmol/L) in preadipocytes.
Affiliation: Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA. Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA egilbert@vt.edu. .
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17: Title: Gene and MicroRNA Expression Are Predictive of Tumor Response in Rectal Adenocarcinoma Patients Treated With Preoperative Chemoradiotherapy.
Authors: Millino, Caterina, et.al. .
Journal: Journal of cellular physiology (J Cell Physiol), Vol. 232 (2): 426-435, 2017 .
Snippet: After PAM, the following eight transcripts were strong predictors of tumor response: TMEM188, ITGA2, NRG, TRAM1, BCL2L13, MYO1B, KLF7, and GTSE1.
Affiliation: Microarray Service, Department of Biology, CRIBI Biotechnology Centre, University of Padua, Padua, Italy. 1st Surgical Clinic, Department of Surgical, Oncological, and Gastroenterological Sciences, University of Padua, Padua, Italy. Department of Radiation Oncology, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy. Department of Pathology, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy. Nanoinspired Biomedicine Lab., Institute of Pediatric Research, Fondazione Città della Speranza, Padova, Italy. Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, Texas. Department of Translational Research, National Cancer Institute, CRO-IRCSS, Aviano, Italy. Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania. Sperimental Oncology, Istituto Oncologico Veneto, IRCCS, Padua, Italy. 1st Surgical Clinic, Department of Surgical, Oncological, and Gastroenterological Sciences, University of Padua, Padua, Italy. puc@unipd.it. .
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18: Title: Correlation of TLR4 and KLF7 in Inflammation Induced by Obesity.
Authors: Wang, Cuizhe, et.al. .
Journal: Inflammation, Vol. 40 (1): 42-51, 2017 .
Snippet: Moreover, compared with the NC group, visceral adipose tissue's mRNA expression levels of TLR4, KLF7, and SRC were significantly higher in the OB group (P < 0.05), and KLF7 was significantly positively correlated with TC, TLR4, MYD88, SRC, and IL-6 (P < 0.05); the protein expression levels of TLR4 and KLF7 were significantly higher than those in the NC group (P < 0.05).
Affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang, 832000, China. Shihezi University School of Medicine in the First Affiliated Hospital Clinical Laboratory, Shihezi, Xinjiang, 832000, China. Endocrinology Department of Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, Xinjiang, 830001, China. Shihezi University School of Medicine, Shihezi, Xinjiang, 832000, China. mayue850911@163.com. Shihezi University School of Medicine, Shihezi, Xinjiang, 832000, China. 2104767820@qq.com. .
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19: Title: Krüpple-like factors 7 and 6a mRNA expression in adult zebrafish central nervous system.
Authors: Bhattarai, Sunil, et.al. .
Journal: Gene expression patterns : GEP (Gene Expr Patterns), Vol. 21 (1): 41-53, 2016 .
Snippet: In this study, we used in situ hybridization to examine Klf7 mRNA (klf7) and Klf6a mRNA (klf6a) expression in adult zebrafish CNS.
Affiliation: Department of Biology and Integrated Bioscience Program, University of Akron, Akron, OH 44325, United States. Department of Biology and Integrated Bioscience Program, University of Akron, Akron, OH 44325, United States. Electronic address: qliu@uakron.edu. .
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20: Title: Sciatic nerve regeneration in KLF7-transfected acellular nerve allografts.
Authors: Wang, Ying, et.al. .
Journal: Neurological research (Neurol Res), Vol. 38 (3): 242-54, 2016 .
Snippet: OBJECTIVE: Krüppel-like Factor 7 (KLF7) is a transcription factor that promotes axon regeneration in the central nervous system.
Affiliation: a Department of Anatomy, Mudanjiang College of Medicine , Mudanjiang College of Medicine , Mudanjiang , China. b Stark Neurosciences Research Institute , Indiana University School of Medicine , Indianapolis , USA. c Department of Pharmacy , Mudanjiang College of Medicine , Tongxiang Road, Aimin District, Mudanjiang 157011 , Heilongjiang , China. .
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