refine search
Saccharomyces cerevisiae 13
 
Saccharomyces cerevisiae Proteins 10
 
Endoplasmic Reticulum 9
 
Membrane Proteins 11
 
endoplasmic reticulum 9
 
Homeostasis 10
 
Sphingolipids 6
 
endoplasmic reticulum membrane 6
 
homeostatic process 9
 
sterol biosynthetic process 5
 
Authors
Locations
Journals
Publication Dates
Find concepts in Knowledge Base
Explore current query
documentsstatisticstop authorclipboard
24 documents found
1: Title: γ-Tocotrienol induces apoptosis in pancreatic cancer cells by upregulation of ceramide synthesis and modulation of sphingolipid transport.
Authors: Palau, Victoria E, et.al. .
Journal: BMC cancer, Vol. 18 (1): 564, 2018 .
Snippet: Modulation ARV1 and previously observed inhibition of the HMG-CoA pathway, contribute to changes in membrane structure and signaling functions, allows the clustering of DR5, effectively initiating apoptosis.
Affiliation: Division of Hematology-Oncology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA. Department of Pharmaceutical Sciences, Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, 37614, USA. Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA. Department of Pediatrics, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA. Division of Hematology-Oncology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA. krishnak@etsu.edu. .
Related Products: order online
2: Title: Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Authors: Gallo-Ebert, Christina, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), 2018 .
Snippet: Arv1-/- animals excreted more fecal cholesterol, free fatty acids, and bile acids.
Affiliation: Institute of Metabolic Disorders. Institute of Metabolic Disorders, United States. Biology, Hope College, United States. Invivotek, United States. Invivotek. Hope College, United States. Rutgers Center for Lipid Research, New Jersey Institute for Food, Nutrition, and Health, Rutgers University, New Brunswick, New Jersey 08901, United States. .
Related Products: order online
3: Title: An ARV1 homologue from a filarial nematode is functional in yeast.
Authors: Herath, H M L P B, et.al. .
Journal: Journal of helminthology (J Helminthol), 2017 .
Snippet: In this study, the ARV1 of an animal filarial parasite, Setaria digitata (SdARV1), was characterized; its cDNA was 761 bp and encoded a protein of 217 amino acids, with a predicted molecular weight of 25 kDa, containing a highly conserved ARV1 homology domain and three transmembrane domains in the bioinformatic analyses.
Affiliation: Department of Chemistry,Faculty of Science,University of Colombo,Colombo 03,Sri Lanka. Molecular Medicine Unit,Faculty of Medicine,University of Kelaniya,Kelaniya,Sri Lanka. .
Related Products: order online
4: Title: Molecular Analysis of Arthrobacter Myovirus vB_ArtM-ArV1: We Blame It on the Tail.
Authors: Kaliniene, Laura, et.al. .
Journal: Journal of virology (J Virol), Vol. 91 (8), 2017 .
Snippet: The genome of ArV1 is a linear, circularly permuted, double-stranded DNA molecule (71,200 bp) with a GC content of 61.6%.
Affiliation: Department of Molecular Microbiology and Biotechnology, Institute of Biochemistry, Life Sciences Centre, Vilnius University, Vilnius, Lithuania laura.kaliniene@bchi.vu.lt. Department of Molecular Microbiology and Biotechnology, Institute of Biochemistry, Life Sciences Centre, Vilnius University, Vilnius, Lithuania. Department of Eukaryote Gene Engineering, Institute of Biotechnology, Life Sciences Centre, Vilnius University, Vilnius, Lithuania. Proteomics Centre, Institute of Biochemistry, Life Sciences Centre, Vilnius University, Vilnius, Lithuania. .
Related Products: order online
5: Title: Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence.
Authors: McCourt, Paula, et.al. .
Journal: G3 (Bethesda, Md.) (G3 (bethesda)), 2016 .
Snippet: Arv1 has a conserved Arv1 homology domain (AHD) that has a zinc-binding domain containing two cysteine clusters.
Affiliation: Institute of Metabolic Disorders; Insitute of Metabolic Disorders; Swansea University Medical School; Invivotek. Institute of Metabolic Disorders; jnickels@venenumbiodesign.com. .
Related Products: order online
6: Title: Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy.
Authors: Palmer, Elizabeth E, et.al. .
Journal: Human molecular genetics (Hum Mol Genet), Vol. 25 (14): 3042-3054, 2016 .
Snippet: Exome sequencing identified a homozygous single nucleotide change that abolishes a splice donor site in the ARV1 gene (c.294
Affiliation: Department of Women and Children's Health, Randwick Campus, University of New South Wales, NSW 2031, Australia. Genetics of Learning Disability Service, Waratah, NSW 2298, Australia. Department of Molecular Physiology and Biophysics. Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA. Sydney Children's Hospital, Randwick, NSW 2031, Australia. Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia. Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Hiroshima University, 1-4-4 Kagamiyam, Higashi-Hiroshima 739-8528, Japan. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. SEALS pathology, Randwick, NSW 2031, Australia. Electron Microscope Unit, Concord Repatriation General Hospital, Concord, NSW 2139, Australia. Kinghorn Centre for Clinical Genomics, Garvan Institute, 370 Victoria St Darlinghurst, Sydney, Australia. St Vincent's Clinical School, University of New South Wales, Sydney, Australia. Department of Molecular Physiology and Biophysics lagor@bcm.edu. .
Related Products: order online
7: Title: Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow.
Authors: Sundvold, Hilde, et.al. .
Journal: Cell cycle (Georgetown, Tex.) (Cell Cycle), Vol. 15 (5): 628-43, 2016 .
Snippet: At the cleavage furrow Arv1 recruits myosin heavy chain 9 (MYH9) and myosin light chain 9 (MYL9) by interacting with IQ-motif-containing GTPase-activating protein (IQGAP1).
Affiliation: a Unit for Cardiac and Cardiovascular Genetics, Department of Medical Genetics, Oslo University Hospital , Oslo , Norway. b Institute of Basic Medical Sciences, Department of Anatomy, University of Oslo , Oslo , Norway. c Department of Chemistry , University of Oslo , Oslo , Norway. d Center for Cancer Biomedicine, Faculty of Medicine, University of Oslo , Montebello, Oslo , Norway. e Institute for Cancer Research, Department of Molecular Cell Biology, The Norwegian Radium Hospital , Montebello, Oslo , Norway. .
Related Products: order online
8: Title: Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure.
Authors: Lagor, W R, et.al. .
Journal: Nutrition & diabetes (Unknown Journal), Vol. 5, 2015 .
Snippet: Arv1 knockout mice exhibited a dramatic lean phenotype, with major reductions in white adipose tissue (WAT) mass and body weight on a chow diet.
Affiliation: Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA. Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Department of Pediatrics, Columbia University Medical Center, New York, NY, USA. .
Related Products: order online
9: Title: Complementation analysis reveals a potential role of human ARV1 in GPI anchor biosynthesis.
Authors: Ikeda, Atsuko, et.al. .
Journal: Yeast (Chichester, England) (Yeast), Vol. 33 (2): 37-42, 2016 .
Snippet: ARV1 is involved in regulating lipid homeostasis but also in the biosynthesis of glycosylphosphatidylinositol (GPI) in Saccharomyces cerevisiae.
Affiliation: Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Japan. Lipid Biology Laboratory and RIKEN, Saitama, Japan. .
Related Products: order online
10: Title: Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families.
Authors: Alazami, Anas M, et.al. .
Journal: Cell reports (Cell Rep), Vol. 10 (2): 148-61, 2015 .
Snippet: This prescreening step led to the identification of 69 recessive genes not previously associated with disease, of which 33 are here described (SPDL1, TUBA3E, INO80, NID1, TSEN15, DMBX1, CLHC1, C12orf4, WDR93, ST7, MATN4, SEC24D, PCDHB4, PTPN23, TAF6, TBCK, FAM177A1, KIAA1109, MTSS1L, XIRP1, KCTD3, CHAF1B, ARV1, ISCA2, PTRH2, GEMIN4, MYOCD, PDPR, DPH1, NUP107, TMEM92, EPB41L4A, and FAM120AOS).
Affiliation: Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia. Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Department of Pediatrics, King Khalid University Hospital and College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia. Department of Pediatrics, King Fahad Medical City, Riyadh 11525, Saudi Arabia. Department of Anatomy and Cell Biology, College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia; Department of Pediatrics, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia. Department of Anatomy and Cell Biology, College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia; Department of Medical Genetics, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia. Department of Pediatrics, King Fahad General Hospital, Jeddah 23325, Saudi Arabia. Department of Pediatrics, Armed Forces Hospital, Khamis Mushayt 62413, Saudi Arabia. Department of Obstetrics & Gynecology, King Faisal Specialist Hospital, Riyadh 11211, Saudi Arabia. Center of Excellence for Genomics, King Abdulaziz City for Science and Technology, Riyadh 11442, Saudi Arabia. Department of Pediatrics, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia. Department of Pediatrics, Security Forces Hospital, Riyadh 12625, Saudi Arabia. Department of Neurosciences, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia. Division of Genetics, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh 14611, Saudi Arabia. Department of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia. Department of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia. Department of Clinical Genetics, Human Genetics and Genome Research Division, National Research Centre, Cairo 12345, Egypt. Department of Pediatrics, Johns Hopkins Aramco Healthcare, Dhahran 34465, Saudi Arabia. Department of Pediatrics, King Khalid University Hospital and College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia; Department of Pediatrics, Children's Hospital, Ain Shams University, Cairo 01234, Egypt. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia; Saudi Human Genome Program, King Abdulaziz City for Science and Technology, Riyadh 11442, Saudi Arabia. Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia; Department of Internal Medicine, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia. Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia; Department of Anatomy and Cell Biology, College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia; Saudi Human Genome Program, King Abdulaziz City for Science and Technology, Riyadh 11442, Saudi Arabia. Electronic address: falkuraya@kfshrc.edu.sa. .
Related Products: order online
11: Title: System analysis of synonymous codon usage biases in archaeal virus genomes.
Authors: Li, Sen, et.al. .
Journal: Journal of theoretical biology (J Theor Biol), Vol. 355, 2014 .
Snippet: Especially, mutational pressure may influence SCUB in SIRV1, SIRV2, ARV1, AFV1, and PhiCh1 viruses, whereas translational selection could play a leading role in HRPV1׳s SCUB.
Affiliation: State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China. State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China. Electronic address: luckyjyj@sina.com.cn. .
Related Products: order online
12: Title: High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions.
Authors: Garay, Erika, et.al. .
Journal: PLoS genetics (Plos Genet), Vol. 10 (2): e1004168, 2014 .
Snippet: We show that lifespan extension by dietary restriction depends on the Swr1 histone-exchange complex and that a functional link between autophagy and the lipid-homeostasis factor Arv1 has an impact on cellular lifespan.
Affiliation: Laboratorio Nacional de Genómica para la Biodiversidad, Centro de Investigación y de Estudios Avanzados del IPN, Irapuato, Guanajuato, Mexico. .
Related Products: order online
13: Title: A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance.
Authors: Ruggles, Kelly V, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 289 (7): 4417-31, 2014 .
Snippet: The ARV1-induced hepatic triglyceride accumulation was accompanied by up-regulation of DGAT1, a triglyceride synthesis gene, and the fatty acid transporter, CD36.
Affiliation: From the Institute of Human Nutrition and. .
Related Products: order online
14: Title: Arv1 regulates PM and ER membrane structure and homeostasis but is dispensable for intracellular sterol transport.
Authors: Georgiev, Alexander G, et.al. .
Journal: Traffic (Copenhagen, Denmark) (Traffic), Vol. 14 (8): 912-21, 2013 .
Snippet: The pan-eukaryotic endoplasmic reticulum (ER) membrane protein Arv1 has been suggested to play a role in intracellular sterol transport.
Affiliation: Department of Biochemistry, Weill Cornell Medical College, New York, NY, USA. .
Related Products: order online
15: Title: Arv1 lipid transporter function is conserved between pathogenic and nonpathogenic fungi.
Authors: Gallo-Ebert, Christina, et.al. .
Journal: Fungal genetics and biology : FG & B (Fungal Genet Biol), Vol. 49 (2): 101-13, 2012 .
Snippet: In the presence of drug, Scarv1 cells are unable to induce ERG gene expression, have an altered pleiotrophic drug response, and are defective in multi-drug resistance efflux pump expression.
Affiliation: Venenum Biodesign, Genesis Biotechnology Group, Hamilton, NJ 08691, United States. .
Related Products: order online
16: Title: Determination of the membrane topology of Arv1 and the requirement of the ER luminal region for Arv1 function in Saccharomyces cerevisiae.
Authors: Villasmil, Michelle L, et.al. .
Journal: FEMS yeast research (Fems Yeast Res), Vol. 11 (6): 524-7, 2011 .
Snippet: Using C-terminal fusion to Suc2-His4, we determined the orientation of full-length Arv1 in the ER membrane.
Affiliation: Target Biology, Venenum Biodesign, Genesis Biotechnology Group, Hamilton, NJ, USA. .
Related Products: order online
17: Title: Loss of subcellular lipid transport due to ARV1 deficiency disrupts organelle homeostasis and activates the unfolded protein response.
Authors: Shechtman, Caryn F, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 286 (14): 11951-9, 2011 .
Snippet: Decreased ARV1 expression in murine macrophages also results in UPR induction, particularly up-regulation of activating transcription factor-4, CHOP (C/EBP homologous protein), and apoptosis.
Affiliation: Institute of Human Nutrition, Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA. .
Related Products: order online
18: Title: The putative lipid transporter, Arv1, is required for activating pheromone-induced MAP kinase signaling in Saccharomyces cerevisiae.
Authors: Villasmil, Michelle L, et.al. .
Journal: Genetics, Vol. 187 (2): 455-65, 2011 .
Snippet: A mutant Ste5, Ste5(Q59L), which binds more tightly to the plasma membrane, suppresses the MAP kinase signaling defects of arv1 cells.
Affiliation: Pharmacogenomics Division, Medical Diagnostics Laboratories, Hamilton, New Jersey 08690, USA. .
Related Products: order online
19: Title: Decreased expression of ARV1 results in cholesterol retention in the endoplasmic reticulum and abnormal bile acid metabolism.
Authors: Tong, Fumin, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 285 (44): 33632-41, 2010 .
Snippet: Knockdown of ARV1 in murine liver and HepG2 cells was associated with accumulation of cholesterol in the ER at the expense of the plasma membrane and suppression of sterol regulatory element-binding proteins and their targets.
Affiliation: Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. .
Related Products: order online
20: Title: Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.
Authors: Kajiwara, Kentaro, et.al. .
Journal: Molecular biology of the cell (Mol Biol Cell), Vol. 19 (5): 2069-82, 2008 .
Snippet: We also provide evidence that ARV1 deletion and mutations in other proteins involved in GPI anchor synthesis affect inositol phosphorylceramide synthesis as well as the intracellular distribution and amounts of sterols, suggesting a role of GPI anchor synthesis in lipid flow from the ER.
Affiliation: Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima 739-8528, Japan. .
Related Products: order online
Page 1 2 
Documents per page: 20 | 50 | 100