refine search
Apolipoprotein C-I 82
 
apolipoprotein E receptor activity 37
 
Genome-Wide Association Study 31
 
Polymorphism, Single Nucleotide 38
 
Alleles 44
 
Triglycerides 36
 
Alzheimer Disease 32
 
Chromosomes, Human, Pair 19 17
 
Apolipoprotein C-II 14
 
Cluster Analysis 29
 
Authors
Locations
Journals
Publication Dates
Find concepts in Knowledge Base
Explore current query
documentsstatisticstop authorclipboard
176 documents found
1: Title: Apolipoprotein E region molecular signatures of Alzheimer's disease.
Authors: Kulminski, Alexander M, et.al. .
Journal: Aging cell, 2018 .
Snippet: region (BCAM, NECTIN2, TOMM40, APOE, and APOC1) in 2,673 AD-affected and 16,246 unaffected individuals from five cohorts.
Affiliation: Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, North Carolina. .
Related Products: order online
2: Title: Peptidome Analysis Reveals Novel Serum Biomarkers for Children with Autism Spectrum Disorder in China.
Authors: Yang, Juan, et.al. .
Journal: Proteomics. Clinical applications (Proteomics Clin Appl), 2018 .
Snippet: 894.34, 4968.59, and 5910.53) with higher expression in ASD group were further identified as peptide regions of Plasma Serine Protease Inhibitor Precursor (SERPINA5), Platelet Factor 4 (PF4), Fatty Acid Binding Protein 1(FABP1), Apolipoprotein C-I Precursor (APOC1), Alpha-fetoprotein Precursor (AFP), Carboxypeptidase B2 (CPB2), Trace Amine-associated Receptor 6 (TAAR6) and Isoform1 of Fibrinogen Alpha Chain Precursor (FGA).
Affiliation: Department of Cell Biology and Genetics, School of Basic Medical Sciences / Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, China. Center of computational systems medicine, School of Biomedical informatics, University of Texas Health Science Center at Houston, Houston, 77030, USA. Department of Pediatrics, Xi'an Children's Hospital, Xi'an, 710003, China. Department of Hepatobiliary Surgery, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, China. .
Related Products: order online
3: Title: DNA methylation in the APOE genomic region is associated with cognitive function in African Americans.
Authors: Liu, Jiaxuan, et.al. .
Journal: BMC medical genomics (Bmc Med Genomics), Vol. 11 (1): 43, 2018 .
Snippet: BACKGROUND: Genetic variations in apolipoprotein E (APOE) and proximal genes (PVRL2, TOMM40, and APOC1) are associated with cognitive function and dementia, particularly Alzheimer's disease.
Affiliation: Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, 4602 SPH Tower, Ann Arbor, MI, 48109-2029, USA. Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA. Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 55905, USA. Department of Neurology, University of Mississippi Medical Center, Jackson, MS, 39126, USA. Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, 4602 SPH Tower, Ann Arbor, MI, 48109-2029, USA. smjenn@umich.edu. Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA. smjenn@umich.edu. .
Related Products: order online
4: Title: Apolipoprotein C1 promotes prostate cancer cell proliferation in vitro.
Authors: Su, Wei-Peng, et.al. .
Journal: Journal of biochemical and molecular toxicology (J Biochem Mol Toxicol), 2018 .
Snippet: Here, we aimed to investigate the carcinogenic effects of apolipoprotein C1 (APOC1) in prostate cancer (PCa).
Affiliation: Department of Urology, Fuzhou General Hospital, Fujian Medical University, Fuzhou, Fujian 350025, People's Republic of China. Department of Presbyatrics, Fuzhou General Hospital, Fujian Medical University, Fuzhou, Fujian 350025, People's Republic of China. Department of Urology, Fuzhou Dongfang Hospital, Xiamen University, Xiamen, Fujian 361005, People's Republic of China. .
Related Products: order online
5: Title: Effects of apoC1 genotypes on the hormonal levels, metabolic profile and PAF-AH activity in Chinese women with polycystic ovary syndrome.
Authors: Zhang, Renjiao, et.al. .
Journal: Lipids in health and disease (Lipids Health Dis), Vol. 17 (1): 77, 2018 .
Snippet: We investigated the relationship between these two variants and the risk of PCOS, evaluated the genotypic effects on clinical, hormonal and metabolic indexes and plasma platelet-activating factor acetylhydrolase (PAF-AH) activity, and defined the association of apoC1 gene variants with apoE ε2/ε3/ε4 polymorphisms.
Affiliation: Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China. Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China. Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China. fanping15@scu.edu.cn. .
Related Products: order online
6: Title: The profiles and networks of miRNA, lncRNA, mRNA, and circRNA in benzo(a)pyrene-transformed bronchial epithelial cells.
Authors: Jiang, Xinhang, et.al. .
Journal: The Journal of toxicological sciences (J Toxicol Sci), Vol. 43 (4): 281-289, 2018 .
Snippet: From miRNA-circRNA, circRNA-mRNA, and lncRNA-circRNA networks analysis, we found that mir-137, circ-RPS5, circ-ZNF292, circ-ERBB2IP, circ-SEMA3C, circ-IGF1R, circ-RTN4, APOC1, and CDKN2A may be of great significance for cell transformation.
Related Products: order online
7: Title: Change of ranibizumab-induced human vitreous protein profile in patients with proliferative diabetic retinopathy based on proteomics analysis.
Authors: Zou, Chen, et.al. .
Journal: Clinical proteomics (Clin Proteomics), Vol. 15, 2018 .
Snippet: Intravitreal level of apolipoprotein C-I (APOC1), serpin peptidase inhibitor clade A member 5 (SERPINA5), tissue inhibitor of metalloproteinases (TIMP2), and keratin 1 (KRT1) were determined by enzyme-linked immuno sorbent assay (ELISA).
Affiliation: 1Department of Ophthalmology, Shanghai General Hospital, Shanghai Key Laboratory of Ocular Fundus Disease, Shanghai Engineering Center for Visual Science and Photomedicine, No. 100 Haining Road, Shanghai, 200080 China. 2Department of Ophthalmology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004 Shaanxi Province China. 3Department of Ophthalmology, Yixing People's Hospital, Jiangsu University, No.75 Tongzhenguan Road, Yixing, 214200 Jiangsu China. Department of Ophthalmology, Changshu the 2nd People's Hospital, Changshu, 215500 Jiangsu China. 5Public Health, Stanford University, Stanford, CA 94305 USA. 6National Center for Protein Science Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 333 Haike Road, Shanghai, 201210 China. .
Related Products: order online
8: Title: ANP32A regulates histone H3 acetylation and promotes leukemogenesis.
Authors: Yang, Xuejing, et.al. .
Journal: Leukemia, 2018 .
Snippet: Notably, significant histone H3 acetylation enrichment was associated with mRNA changes in lipid-related genes, including APOC1, PCSK9, P2RX1, and LPPR3.
Affiliation: Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China. University of Chinese Academy of Sciences, Beijing, China. College of Life Sciences, Key Laboratory of Cell Hemostasis of Hubei Province, Wuhan University, Wuhan, Hubei, China. Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Blood Diseases Institute, The Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu, China. Department of Hematology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China. Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China. wangqf@big.ac.cn. University of Chinese Academy of Sciences, Beijing, China. wangqf@big.ac.cn. College of Life Sciences, Key Laboratory of Cell Hemostasis of Hubei Province, Wuhan University, Wuhan, Hubei, China. z-huang@whu.edu.cn. .
Related Products: order online
9: Title: Prediction of cholesterol ratios within a Korean population.
Authors: Lee, Jin Sol, et.al. .
Journal: Royal Society open science (R Soc Open Sci), Vol. 5 (1): 171204, 2018 .
Snippet: After performing the 10-fold cross-validation, the six SNPs (rs4420638 (APOC1), rs12421652 (BUD13), rs17411126 (LPL), rs6589566 (ZPR1), rs16940212 (LOC101928635) and rs10852765 (ABCA8)) were finally selected for predicting cholesterol ratios.
Affiliation: Department of Life Science, Sogang University, Baekbumro 35, Mapo-gu, Seoul 04107, Republic of Korea. Research Institute for Basic Science, Sogang University, Mapo-gu, Seoul, 121-742, Republic of Korea. Department of Genetic Epidemiology, SNP Genetics, Inc., Taihard building 1007, Sogang University, Baekbumro 35, Mapo-gu, Seoul, Republic of Korea. .
Related Products: order online
10: Title: Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis.
Authors: Mao, Chunhong, et.al. .
Journal: Journal of proteomics and genomics research (J Proteom Genom Res), Vol. 2 (1): 1-12, 2017 .
Snippet: The top ranking genes included some known to be involved with cardiovascular disease (APOA1, APOA5, APOB, APOC1, APOC2, APOE, CDKN1A, CXCL12, SCARB1, SMARCA4 and TERT), and others that are less obvious and require further investigation (TP53, MYC, PPARG, YWHAQ, RB1, AR, ESR1, EGFR, UBC and YWHAZ).
Affiliation: Biocomplexity Institute of Virginia Tech, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. Center for Genomics & Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Division of Hematology, Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21205, USA. Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA. Heart institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048. Department of Pathology, LSU Health New Orleans, New Orleans, LA 70112, USA. Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA. Department of Cardiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. .
Related Products: order online
11: Title: Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.
Authors: Yashin, Anatoliy I, et.al. .
Journal: Experimental gerontology (Exp Gerontol), 2017 .
Snippet: The results of analyses confirmed strong associations of genetic variants from well-known genes APOE, TOMM40, PVRL2 (NECTIN2), and APOC1 with AD.
Affiliation: Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, 2024 W. Main Street, Durham, NC 27705, USA. Electronic address: aiy@duke.edu. Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, 2024 W. Main Street, Durham, NC 27705, USA. Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, 2024 W. Main Street, Durham, NC 27705, USA. Electronic address: svo@duke.edu. .
Related Products: order online
12: Title: Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development.
Authors: Yokota, Chika, et.al. .
Journal: The International journal of developmental biology (Int J Dev Biol), Vol. 61 (6-7): 415-425, 2017 .
Snippet: Here, we have identified apolipoprotein C-I (apoc1) in a screen for genes regulated by Wnt/Ctnnb1 signaling in late blastula stage Xenopus tropicalis embryos.
Affiliation: Institute for Cancer Research Ltd, Stockholm, Sweden. chika.yokota@licr.ki.se. .
Related Products: order online
13: Title: The association between six genetic variants and blood lipid levels in pregnant Chinese Han women.
Authors: Nie, Min, et.al. .
Journal: Journal of clinical lipidology (J Clin Lipidol), Vol. 11 (4): 938-944, 2017 Jul - Aug .
Snippet: Six SNPs (rs1260326 in GCKR, rs1800775 in CETP, rs515135 in APOB, rs1800588 in LIPC, rs964184 in ZPR1, and and rs4420638 in APOC1 of each participant were genotyped using TaqMan allelic discrimination assays.
Affiliation: Key laboratory of Endocrine, Department of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. Electronic address: maliangkun@pumch.cn. .
Related Products: order online
14: Title: Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions.
Authors: Weller, Romy, et.al. .
Journal: Journal of virology (J Virol), Vol. 91 (18), 2017 .
Snippet: Transcriptome sequencing (RNA-seq) revealed abundant coexpression of ApoE, ApoB, ApoA1, ApoA2, ApoC1, ApoC2, and ApoC3 in primary hepatocytes and in Huh-7.5 cells.
Affiliation: Institute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hanover, Germany. Department of General, Visceral and Transplant Surgery, Hanover Medical School, Hanover, Germany. German Centre for Infection Research, Partner Site Hanover-Braunschweig, Hanover, Germany. Institute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hanover, Germany thomas.pietschmann@twincore.de. .
Related Products: order online
15: Title: Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort.
Authors: Li, Jin, et.al. .
Journal: Neurobiology of aging (Neurobiol Aging), Vol. 57, 2017 .
Snippet: The GWAS results replicated the previously reported AD-related genes APOE, APOC1, and TOMM40, as well as identified 14 novel genes, which showed genome-wide statistical significance.
Affiliation: College of Automation, Harbin Engineering University, Harbin, China. College of Automation, Harbin Engineering University, Harbin, China; College of Information Engineering, Northeast Dianli University, Jilin, China. Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA; Department of BioHealth Informatics, Indiana University School of Informatics and Computing, Indianapolis, IN, USA. Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA. College of Automation, Harbin Engineering University, Harbin, China. Electronic address: lh@hrbeu.edu.cn. Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA; Department of BioHealth Informatics, Indiana University School of Informatics and Computing, Indianapolis, IN, USA. Electronic address: shenli@iu.edu. .
Related Products: order online
16: Title: Replication and fine-mapping of genetic predictors of lipid traits in African-Americans.
Authors: Feng, QiPing, et.al. .
Journal: Journal of human genetics (J Hum Genet), Vol. 62 (10): 895-901, 2017 .
Snippet: Furthermore, we identified two loci significantly associated with non-HDL-C: APOE/APOC1/TOMM40 and PCSK9.
Affiliation: Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA. Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. Department of Pharmacology, Vanderbilt University, Nashville, TN, USA. .
Related Products: order online
17: Title: A generalized association test based on U statistics.
Authors: Wei, Changshuai, et.al. .
Journal: Bioinformatics (Oxford, England) (Bioinformatics), Vol. 33 (13): 1963-1971, 2017 .
Snippet: We further performed a whole genome sequencing (WGS) scan for Alzherimer's disease neuroimaging initiative data, identifying three genes, APOE , APOC1 and TOMM40 , associated with imaging phenotype.
Affiliation: Department of Biostatistics and Epidemiology, University of North Texas Health Science Center, Fort Worth, TX 76107. Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI 48824, USA. .
Related Products: order online
18: Title: Effect of two lipid-lowering strategies on high-density lipoprotein function and some HDL-related proteins: a randomized clinical trial.
Authors: Lee, Chan Joo, et.al. .
Journal: Lipids in health and disease (Lipids Health Dis), Vol. 16 (1): 49, 2017 .
Snippet: The baseline cholesterol efflux capacity correlated positively with apolipoprotein (apo)A1 and C3, whereas apoA1 and apoC1 showed inverse associations with VCAM-1 expression.
Affiliation: Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea. Gachon Cardiovascular Research Institute, Gachon University, Incheon, Korea. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea. Interdisciplinary program of Integrated Biotechnology, Sogang University, Seoul, Korea. Department of chemistry, Sookmyung Women's University, Seoul, Korea. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea. jelee9137@kist.re.kr. Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. shl1106@yuhs.ac. Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea. shl1106@yuhs.ac. .
Related Products: order online
19: Title: The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster.
Authors: Subramanian, Shobana, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1863 (3): 810-816, 2017 .
Snippet: Low (nM) concentrations of pioglitazone (Pio) decreased transcription of TOMM40, APOE, and APOC1 genes, with the lowest mRNA levels for each gene observed at 1.5nM.
Affiliation: Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA. Center for Genomic and Computational Biology, Duke University Medical Center, Durham, NC 27710, USA. Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA; Zinfandel Pharmaceuticals, Chapel Hill, NC, USA. Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA; Center for Genomic and Computational Biology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: o.chibafalek@duke.edu. .
Related Products: order online
20: Title: Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup.
Authors: Kim, Taehyeung, et.al. .
Journal: PloS one, Vol. 12 (1): e0168137, 2017 .
Snippet: The associations of the GWAS variants with lipid ratios were replicated in the validation stage: for the log[TG]:HDLC ratio, rs6589566 near APOA5 and rs4244457 and rs6586891 near LPL; for the LDLC:HDLC ratio, rs4420638 near APOC1 and rs17445774 near C2orf47; and for the non-HDLC:HDLC ratio, rs6589566 near APOA5.
Affiliation: Mibyeong Research Center, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon, Republic of Korea. .
Related Products: order online
Page 1 2 3 … 9 
Documents per page: 20 | 50 | 100