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232 documents found
1: Title: Effect of TEAD4 on multilineage differentiation of muscle-derived stem cells.
Authors: Wang, Jinze, et.al. .
Journal: American journal of translational research (Am J Transl Res), Vol. 10 (3): 998-1011, 2018 .
Snippet: During adipogenic differentiation, TEAD4-KD systematically impaired upregulation of TEAD1, TEAD2, and TEAD3, as well as the activation of C/EBP2, ADD1, and PPARγ as the key transcription factors for adipogenic differentiation.
Affiliation: State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia UniversityHohhot 010070, Inner Mongolia, People's Republic of China. School of Basic Medical Sciences, Inner Mongolia Medical CollegeHohhot 010110, People's Republic of China. .
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2: Title: Genetic variants conferring susceptibility to gastroschisis: a phenomenon restricted to the interaction with the environment?
Journal: Pediatric surgery international (Pediatr Surg Int), 2018 .
Snippet: The rs4961 (ADD1), rs5443 (GNB3), rs1042713, and rs1042714 (ADRB2) were significantly associated with gastroschisis.
Affiliation: Departamento de Genética, Facultad de Medicina y Hospital Universitario José Eleuterio González, Universidad Autónoma de Nuevo León, Ave. Madero y Gonzalitos S/N Col. Mitras Centro, CP 64460, Monterrey, Nuevo León, Mexico. vm_salinas7@hotmail.com. Departamento de Sistemas y Computación, Instituto Tecnológico de Tijuana, Calzada del Tecnológico S/N Fracc. Tomas Aquino, CP 22414, Tijuana, Baja California, Mexico. Facultad de Enfermería, Universidad Autónoma de Nuevo León, Dr. José Eleuterio González 1500, Mitras Norte, CP 64460, Monterrey, Nuevo León, Mexico. Departamento de Genética, Facultad de Medicina y Hospital Universitario José Eleuterio González, Universidad Autónoma de Nuevo León, Ave. Madero y Gonzalitos S/N Col. Mitras Centro, CP 64460, Monterrey, Nuevo León, Mexico. .
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3: Title: Genetic Variants in ADD1 Gene and their Associations with Growth Traits in Cattle.
Authors: Huang, Yong-Zhen, et.al. .
Journal: Animal biotechnology (Anim Biotechnol), 2018 .
Snippet: The α-adducin (ADD1) is a subunit of adducin which is a cytoskeleton heterodimeric protein.
Affiliation: a Institute of Cellular and Molecular Biology, School of Life Sciences , Jiangsu Normal University , Xuzhou , Jiangsu , China. b Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology , Northwest A&F University , Yangling , Shaanxi , China. c College of Life Sciences , Institute for Conservation and Utilization of Agro-Bioresources in Dabie Mountains, Xinyang Normal University , Xinyang , Henan , China. d Animal Health Supervision in Henan Province , Zhengzhou , Henan , China. e Bureau of Animal Husbandry of Biyang County , Biyang , Henan , China. .
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4: Title: Over-expression of PPAR-γ2 gene enhances the adipogenic differentiation of hemangioma-derived mesenchymal stem cells in vitro and in vivo.
Authors: Yuan, Si-Ming, et.al. .
Journal: Oncotarget, Vol. 8 (70): 115817-115828, 2017 .
Snippet: Results: In the in vitro tests, Hem-MSCs with overexpression of PPAR-γ2 gene showed enhanced adipogenic differentiation with increased expression of adipogenic-related genes, including PPAR-γ2, ADD1, LPL, and CEBPA genes.
Affiliation: Department of Plastic Surgery and Vascular Biology Lab, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu 210002, China. Department of Plastic Surgery, Children's Hospital, Nanjing, Jiangsu 210008, China. .
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5: Title: Acetate alters the process of lipid metabolism in rabbits.
Authors: Fu, C, et.al. .
Journal: Animal : an international journal of animal bioscience (Animal), 2017 .
Snippet: In adipose, acetate injection significantly up-regulated the gene expression of peroxisome proliferator-activated receptor gamma (PPARγ), CCAAT/enhancer-binding protein α (C/EBPα), differentiation-dependent factor 1 (ADD1), adipocyte protein 2 (aP2), carnitine palmitoyltransferase 1 (CPT1), CPT2, hormone-sensitive lipase (HSL), G protein-coupled receptor (GPR41), GPR43, adenosine monophosphate-activated protein kinase α1 (AMPKα1), adiponectin receptor (AdipoR1), AdipoR2 and leptin receptor.
Affiliation: 1Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention,Department of Animal Science and Technology,Shandong Agricultural University,Taian 271018,China. .
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6: Title: Relationship between ADD1 Gly460Trp gene polymorphism and essential hypertension in Madeira Island.
Authors: Sousa, Ana Célia, et.al. .
Journal: Medicine (Medicine (baltimore)), Vol. 96 (42): e7861, 2017 .
Snippet: The genetic variant of the alpha-adducin gene (ADD1) has been described as a risk factor for EH, but with controversial results.The objective of this study was to evaluate the association of ADD1 (Gly460Trp) gene polymorphism with the EH risk in a population from Madeira Island.A case-control study with 1614 individuals of Caucasian origin was performed, including 817 individuals with EH and 797 controls.
Affiliation: aFunchal Hospital Center, Research Unit, Avenida Luís de Camões, n° 57, Funchal, Madeira bFaculty of Medical Sciences, New University of Lisbon, Campo dos Mártires da Pátria, Lisboa cLaboratory of Human Genetics, Madeira University, Campus da Penteada, Funchal-Madeira, Portugal. .
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7: Title: Sez6l2 regulates phosphorylation of ADD and neuritogenesis.
Authors: Yaguchi, Hiroaki, et.al. .
Journal: Biochemical and biophysical research communications (Biochem Biophys Res Commun), Vol. 494 (1-2): 234-241, 2017 .
Snippet: Increasing evidence shows that immune-mediated mechanisms may contribute to the pathogenesis of central nervous system disorders including cerebellar ataxias, as indicated by the aberrant production of neuronal surface antibodies.
Affiliation: Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan; Department of Biochemistry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan; Department of Neurology, Brain Science Center, Sapporo City General Hospital, Sapporo, Hokkaido, Japan. Electronic address: yaguchi-h@pop.med.hokudai.ac.jp. Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. Department of Biochemistry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. Department of Neurology, Brain Science Center, Sapporo City General Hospital, Sapporo, Hokkaido, Japan. Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Fukuoka, Japan. Department of Anatomy, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. Department of Biochemistry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. Electronic address: hatas@med.hokudai.ac.jp. .
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8: Title: NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.
Journal: PloS one, Vol. 12 (10): e0185780, 2017 .
Snippet: The aberrant spindle structure is concomitant with the disruption in localization and protein levels of myosin X (MYO10) and α-adducin (ADD1), both of which are implicated in the regulation of spindle formation during mitosis.
Affiliation: Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University, Ithaca, New York, United States of America. .
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9: Title: Synergistic Association of Genetic Variants with Environmental Risk Factors in Susceptibility to Essential Hypertension.
Authors: Sousa, Ana Célia, et.al. .
Journal: Genetic testing and molecular biomarkers (Genet Test Mol Biomarkers), 2017 .
Snippet: RESULTS: The best model indicates that the interactions among the ADD1 rs4961 640T allele, diabetes, and obesity (body mass index ≥30) increase approximately four-fold the risk of EH (odds ratio = 3.725; 95% confidence interval: 2.945-4.711;
Affiliation: 1 Unidade de Investigação, Hospital Doutor Nélio Mendonça , Funchal, Portugal . 2 Laboratório de Genética Humana, Universidade da Madeira , Funchal, Portugal . 3 Faculty of Medical Sciences, New University of Lisbon , Lisboa, Portugal . .
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10: Title: Cryoprotective effect of resveratrol on DNA damage and crucial human sperm messenger RNAs, possibly through 5' AMP-activated protein kinase activation.
Journal: Cell and tissue banking (Cell Tissue Bank), 2017 .
Snippet: This work aimed at investigating the effect of resveratrol on (1) DNA integrity and (2) fertilizing capacity of sperm by quantifying the presence of key paternal transcripts considered as markers for male fertility (protamine 1 [PRM1] and protamine 2 [PRM2]) and pregnancy success (adducin 1 alpha [ADD1]) in cryopreserved human spermatozoa through modulation of AMP-activated protein kinase (AMPK).
Affiliation: Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, 1417613151, Iran. Department of Infertility, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, 1417613151, Iran. Famidi@sina.tums.ac.ir. Department of Infertility, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Famidi@sina.tums.ac.ir. .
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11: Title: α-Adducin gene promoter DNA methylation and the risk of essential hypertension.
Authors: Bayoumy, Nervana M K, et.al. .
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) (Clin Exp Hypertens), 2017 .
Snippet: Our results showed that females have a higher ADD1 DNA methylation than males and a significantly lower CpG1 methylation level is associated with increased risk of EH among them.
Affiliation: a Physiology Department, College of Medicine, Center of Excellence in Thrombosis & Hemostasis , King Saud University , Riyadh , Kingdom of Saudi Arabia. b Clinical and Chemical Pathology Department, Faculty of Medicine , Suez Canal University , Ismailia , Egypt. c Internal Medicine Department, Faculty of Medicine , Suez Canal University , Ismailia , Egypt. .
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12: Title: Adducin family proteins possess different nuclear export potentials.
Authors: Liu, Chia-Mei, et.al. .
Journal: Journal of biomedical science (J Biomed Sci), Vol. 24 (1): 30, 2017 .
Snippet: In addition, the interaction of ADD1 with RNA polymerase II and zinc-finger protein 331 implicates a potential role for ADD1 in the regulation of transcription.
Affiliation: Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan. Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, Taiwan. Institue of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan. Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan. hcchen@nchu.edu.tw. Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, Taiwan. hcchen@nchu.edu.tw. Institue of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan. hcchen@nchu.edu.tw. Rong-Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan. hcchen@nchu.edu.tw. Institute of Biochemistry and Molecular Biology, National Yang Ming University, No. 155, Sec. 2, Li-Nong St, Taipei, 11221, Taiwan. hcchen@nchu.edu.tw. .
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13: Title: Reversible Oxidative Addition at Carbon.
Authors: Eichhorn, Antonius F, et.al. .
Journal: Angewandte Chemie (International ed. in English) (Angew Chem Int Ed Engl), Vol. 56 (34): 10209-10213, 2017 .
Snippet: The reaction with NHCs leads to the reversible formation of thermally stable Lewis acid/base adducts Ar-B(OR)2 ⋅NHC (Add1-Add6).
Affiliation: Institut für Anorganische Chemie and Institute for Sustainable Chemistry & Catalysis with Boron, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074, Würzburg, Germany. .
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14: Title: Association between alpha-adducin gene rs4963 polymorphism and hypertension risk in Asian population: a meta-analysis.
Authors: Qu, Y-L, et.al. .
Journal: Cellular and molecular biology (Noisy-le-Grand, France) (Cell Mol Biol (noisy-le-grand)), Vol. 62 (13): 62-64, 2016 .
Snippet: The results showed that Chinese with ADD1 rs4963 polymorphism showed an increased hypertension risk (OR = 1.28; 95%CI, 1.09-1.51;
Affiliation: Department of Anesthesiology, No. 401 Hospital of PLA, Qingdao, China. Emergency Department, Qilu Hospital of Shandong University, Qingdao, China. Department of Medical Affairs, No. 401 Hospital of PLA, Qingdao, China. .
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15: Title: The impacts of the interaction of genetic variation, CYP11β2 and NEDD4L, with sodium intake on pediatric obesity with gender difference: a 3-year panel study.
Authors: Lee, M, et.al. .
Journal: International journal of obesity (2005) (Int J Obes (lond)), Vol. 41 (4): 542-550, 2017 .
Snippet: Backgrounds/Objectives:This panel study was to predict the incidences of pediatric obesity by the interaction of sodium (Na) intake and nine single-nucleotide polymorphisms (SNPs) of salt-sensitive genes (SSGs), ACE(angiotensin-converting enzyme), ADD1 G460W,AGT M235T,CYP11β2 (cytochrome P450 family 11-subfamily β-2, -aldosterone synthase),GNB3 C285T,GRK4(A142V)(G-protein-coupled receptor kinases type 4),GRK4 (A486V),NEDD4L (neural precursor cell expressed developmentally downregulated 4 like; rs2288774) and SLC12A3 (solute carrier family 12 (Na/Cl transporters)-member 3), selected from genome-wide association study.
Affiliation: Department of Food and Nutrition, Sungshin Women's University, Food and Nutrition (A-658), Sungshin University, Seoul, Republic of Korea. Division of Statistics, Research Institute of Obesity Sciences, Sugnshin Women's University, Seoul, Republic of Korea. Division of Nutrition and Metabolism Research, Korea Food Research Institute, Gyeonggi-do, Republic of Korea. .
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16: Title: Deep-targeted exon sequencing reveals renal polymorphisms associate with postexercise hypotension among African Americans.
Authors: Pescatello, Linda S, et.al. .
Journal: Physiological reports (Physiol Rep), Vol. 4 (19), 2016 .
Snippet: We found variants from the Angiotensinogen-Converting Enzyme (ACE), Angiotensin Type 1 Receptor (AGTR1), Aldosterone Synthase (CYP11B2), and Adducin (ADD1) genes exhibited intensity-dependent associations with the ambulatory blood pressure (BP) response following acute exercise, or postexercise hypotension (PEH).
Affiliation: Department of Kinesiology, University of Connecticut, Storrs, Connecticut Linda.Pescatello@uconn.edu. Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut. Department of Statistics, University of Connecticut, Storrs, Connecticut. School of Nursing, Yale University, New Haven, Connecticut. Department of Kinesiology, University of Connecticut, Storrs, Connecticut. Department of Preventive Cardiology, Hartford Hospital, Hartford, Connecticut. Department of Physical Activity Sciences, Rio de Janeiro State University, Rio de Janeiro, Brazil. .
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17: Title: Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer.
Authors: Deckers, Ivette A G, et.al. .
Journal: Scientific reports (Sci Rep), Vol. 6, 2016 .
Snippet: We investigated the ion transport mechanism (ITM) in renal cell cancer (RCC) etiology using gene-environment interactions between candidate single nucleotide polymorphisms (SNPs) and associated environmental factors, including dietary intakes of sodium, potassium and fluid, hypertension and diuretic medication.
Affiliation: Departments of Epidemiology School for Oncology and Developmental Biology (GROW), Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands. Departments of Pathology, School for Oncology and Developmental Biology (GROW), Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands. Department of Toxicology, School for Nutrition, Toxicology and Metabolism (NUTRIM), MUMC, Maastricht, The Netherlands. Department of Medical Informatics, Universitätsklinikum Aachen, Germany. Center for Environmental Sciences, Hasselt University, Diepenbeek, Belgium. .
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18: Title: Gene variants as risk factors for gastroschisis.
Authors: Padula, Amy M, et.al. .
Journal: American journal of medical genetics. Part A (Am J Med Genet A), Vol. 170 (11): 2788-2802, 2016 .
Snippet: NOS3, ADD1, ICAM1, ICAM4, and ICAM5 warrant further investigation in additional populations and with the interaction of additional environmental exposures.
Affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California. amy.padula@ucsf.edu. Department of Pediatrics, Stanford University School of Medicine, California. UCSF Benioff Children's Hospital Oakland, Oakland, California. .
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19: Title: Association of interactions between dietary salt consumption and hypertension-susceptibility genetic polymorphisms with blood pressure among Japanese male workers.
Authors: Imaizumi, Takahiro, et.al. .
Journal: Clinical and experimental nephrology (Clin Exp Nephrol), Vol. 21 (3): 457-464, 2017 .
Snippet: This study examined the SNPs AGT rs699 (Met235Thr), ADD1 rs4961 (Gly460Trp), NPPA rs5063 (Val32Met), GPX1 rs1050450 (Pro198Leu), and AGTR1 rs5186 (A1166C) in relation to hypertension and salt sensitivity.
Affiliation: Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan. mando@med.nagoya-u.ac.jp. Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan. Department of CKD Initiatives, Nagoya University Graduate School of Medicine, Nagoya, Japan. Department of Biotechnology, Graduate School of Engineering, Nagoya University, Nagoya, Japan. Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan. Safety and Health Promotion Division, Toyota Motor Corporation, Toyota, Japan. R & D management Division, Toyota Motor Corporation, Toyota, Japan. Innovative Research Center for Preventative Medical Engineering, Nagoya University, Nagoya, Japan. .
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20: Title: The Influence of Tetracycline Inducible Targeting Rat PPARγ Gene Silencing on the Osteogenic and Adipogenic Differentiation of Bone Marrow Stromal Cells.
Authors: Feng, Xiaobo, et.al. .
Journal: Current pharmaceutical design (Curr Pharm Des), Vol. 22 (41): 6330-6338, 2016 .
Snippet: The expression of the adipogenic factors adipocyte determination and differentiation-dependent factor 1 (ADD1) and recombinant CCAAT/enhancer binding protein alpha (C/EBPα) were decreased as measured by RT-PCR and Western blot assay following PPARγ silencing.
Affiliation: Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, Jiefang Avenue, No.1277, 430022, China. .
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