Divergent pathways lead to ESCRT-III-catalyzed membrane fission.
Bristol, United Kingdom. In Trends Biochem Sci, 2011
Although receptor sorting at the endosomal membrane producing MVBs employs the regulated assembly of ESCRT-0 followed by ESCRT-I, -II, -III and the vacuolar protein sorting (VPS)4 complex, other ESCRT-catalyzed processes require only a subset of complexes which commonly includes ESCRT-III and VPS4.
Structure and function of ESCRT-III.
Grenoble, France. In Biochem Soc Trans, 2009
Progress towards the understanding of the structures and function of ESCRT-III, its activation, its regulation by accessory factors and its role in abscission of membrane enveloped structures in concert with VPS4 are discussed.
Maturation of autophagic vacuoles in Mammalian cells.
Kiel, Germany. In Autophagy, 2005
The list of newly discovered molecules that regulate the maturation of autophagosomes to degradative autolysosomes includes the AAA ATPase SKD1, the small GTP binding protein Rab7, and possibly also the Alzheimer-linked presenilin 1.