Vitamin D-Binding Protein
Nutrient interface with biology and aging.
Saint Louis, United States. In Curr Opin Clin Nutr Metab Care, Jan 2016
The understanding of the role of ethnicity in the levels of vitamin D-binding protein has questioned the measurement of 25(OH)vitamin D by itself.
Vitamin D and thyroid diseases.
Praha, Czech Republic. In Physiol Res, 2014
A higher risk of Graves´ disease development is also associated with several polymorphisms in the gene encoding for vitamin D binding protein and for the specific receptor of active form of vitamin D - 1,25-(OH)(2)D(3) in the respective target cells.
Urinary biomarkers for the non-invasive diagnosis of endometriosis.
Auckland, New Zealand. In Cochrane Database Syst Rev, 2014
Five studies evaluated the diagnostic performance of four urinary biomarkers for endometriosis, including three biomarkers distinguishing women with and without endometriosis (enolase 1 (NNE); vitamin D binding protein (VDBP); and urinary peptide profiling); and one biomarker (cytokeratin 19 (CK 19)) showing no significant difference between the two groups.
Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes.
Seattle, United States. In Jama, 2012
Substrate 25-hydroxyvitamin D must be converted to 1,25-dihydroxyvitamin D for full biological activity, and complex metabolic pathways suggest that interindividual variability in vitamin D metabolism may alter the clinical consequences of measured serum 25-hydroxyvitamin D. OBJECTIVE: To investigate whether common variation within genes encoding the vitamin D-binding protein, megalin, cubilin, CYP27B1, CYP24A1, and the vitamin D receptor (VDR) modify associations of low 25-hydroxyvitamin D with major clinical outcomes.