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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 03 Jul 2015.

Vimentin

vimentin
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009] (from NCBI)
Top mentioned proteins: E-cadherin, Actin, CAN, HAD, cytokeratin
Papers using vimentin antibodies
Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns.
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Bogyo Matthew, In PLoS ONE, 2010
... The monoclonal antibody for E-cadherin was from BD Pharmingen (Burlington, ON), the monoclonal antibody for vimentin was from Dako (clone 3B4, Burlington, ON), ...
An orally available small molecule inhibitor of c-Met, PF-2341066, reduces tumor burden in a pre-clinical model of ovarian cancer metastasis.
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Lengyel E et al., In Oncogene, 2009
... Louis, MO), Ki-67 antibody from LabVision (Fremont, CA), vimentin, collagen IV and laminin antibodies were from Dako Cytomation (Carpinteria, CA) ...
The role of caveolin-1 in prostate cancer: clinical implications
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Hong Wanjin, In PLoS ONE, 2009
... Antibodies to E-cadherin and vimentin were from Cell Signaling Technology ...
Methylation-dependent binding of the Epstein–Barr virus BZLF1 protein to viral promoters
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Mallet François et al., In DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes, 2008
... It was found that 98% of the cells were vimentin positive and also positive for a monoclonal antibody against specific fibroblast antigen (clone ASO2, Dianova, Hamburg, Germany) ...
Polymerase chain reaction detection of Trypanosoma cruzi in Macaca fascicularis using archived tissues.
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Rodriguez Ana, In PLoS Neglected Tropical Diseases, 2008
... Anti-fd bacteriophage antibody (Sigma Aldrich), recombinant cytokeratin 18, cytokeratin 8, cytokeratin 20 and vimentin were commercially obtained (Cell Sciences).
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Papers on vimentin
PRRS virus receptors and their role for pathogenesis.
Review
New
Yoo et al., Urbana, United States. In Vet Microbiol, 12 Jul 2015
At least six cellular molecules have been described so far as putative receptors for PRRSV, and they include heparan sulfate, vimentin, CD151, sialoadhesin (CD169; siglec-1), dendritic cell-specific intercellular adhesion melecule-3-grabbing non-integrin (DC-SIGN; CD209), and CD163 (SRCR, cysteine-rich scavenger receptor).
Hybrid-polymerase chain reaction to identify novel target genes of miR-134 in paclitaxel resistant human ovarian carcinoma cells.
New
Chang et al., Shenyang, China. In Oncol Lett, 30 Jun 2015
By applying hybrid-PCR, 8 putative target genes of miR-134 in SKOV3-TR30 cells were identified, including C16orf72, PNAS-105, SRM, VIM, F-box protein 2, GAPDH, PRPF6 and RPL41.
Collecting duct carcinoma of the kidney: A case report.
New
Wang et al., Changchun, China. In Oncol Lett, 30 Jun 2015
Immunohistochemical staining revealed that the tumor cells were positive for epithelial membrane antigen and cytokeratin (CK)7, while they reacted focally with vimentin.
Protein lipoxidation: Detection strategies and challenges.
Review
New
Pérez-Sala et al., Milano, Italy. In Redox Biol, 21 Jun 2015
Under basal conditions, protein lipoxidation can contribute to normal cell homeostasis and participate in signaling or adaptive mechanisms, as exemplified by lipoxidation of Ras proteins or of the cytoskeletal protein vimentin, both of which behave as sensors of electrophilic species.
Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens.
Review
New
Toes et al., Leiden, Netherlands. In Nat Rev Rheumatol, 19 Jun 2015
In RA, understanding of the pathogenetic role of B-cell responses to citrullinated antigens, including vimentin, fibrinogen and α-enolase, is rapidly growing.
Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer.
New
Ferlini et al., Roma, Italy. In Oncotarget, 15 Jun 2015
In hypoglycemic conditions ZEB2 expression decreased, along with ZEB1, vimentin and cytoplasmic HuR, and a reduced cellular migration ability was observed.
Olfactory ensheathing cell tumor: A case report and review of the literature.
New
Hong et al., Changchun, China. In Oncol Lett, May 2015
The tumor was immunopositive for vimentin and S-100, and immunonegative for epithelial membrane antigen and Leu-7.
CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development.
New
Sebens et al., Kiel, Germany. In Oncoimmunology, Apr 2015
Particularly in the presence of activated T-effs, H6c7 cells acquired a spindle-shaped morphology, reduced E-cadherin expression, and elevated expression of the mesenchymal proteins vimentin, L1CAM, and ZEB-1.
Roles and Potential Clinical Applications of Intermediate Filament Proteins in Brain Tumors.
Review
New
Skalli et al., Memphis, United States. In Semin Pediatr Neurol, Mar 2015
In addition, brain cancer cells may also contain vimentin, nestin, and synemin, which are the IF proteins found in neural progenitor cells.
The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract.
Review
New
Wojnicz et al., Katowice, Poland. In Prz Gastroenterol, Dec 2014
Vimentin is an intermediate filament protein normally expressed in cells of mesenchymal origin, e.g.
Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy.
New
Impact
Weitz et al., Cambridge, United States. In Cell, Sep 2014
We further demonstrate that vimentin acts globally to anchor organelles against randomly fluctuating forces in the cytoplasm, with no effect on their magnitude.
Post-translational modifications of intermediate filament proteins: mechanisms and functions.
Review
New
Impact
Omary et al., Ann Arbor, United States. In Nat Rev Mol Cell Biol, Mar 2014
IFs, including nuclear lamins and those in the cytoplasm (keratins, vimentin, desmin, neurofilaments and glial fibrillary acidic protein, among others), are functionally regulated by post-translational modifications (PTMs).
Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non-small-cell lung cancer.
Impact
Farace et al., Villejuif, France. In J Clin Oncol, 2013
ALK-rearranged CTCs and tumor specimens were characterized for epithelial (cytokeratins, E-cadherin) and mesenchymal (vimentin, N-cadherin) marker expression.
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation.
Impact
Levine et al., Dallas, United States. In Science, 2012
Akt-mediated phosphorylation of Beclin 1 enhanced its interactions with 14-3-3 and vimentin intermediate filament proteins, and vimentin depletion increased autophagy and inhibited Akt-driven transformation.
Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly.
GeneRIF
Strelkov et al., Leuven, Belgium. In Proc Natl Acad Sci U S A, 2012
analysis of atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
GeneRIF
Hunt et al., Davis, United States. In J Biol Chem, 2012
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
Ablation of vimentin results in defective steroidogenesis.
GeneRIF
Kraemer et al., Palo Alto, United States. In Endocrinology, 2012
vimentin ablation results in defective steroidogenesis
Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation.
GeneRIF
Bayless et al., College Station, United States. In Angiogenesis, 2012
pro-angiogenic signals converge to activate calpain-dependent vimentin cleavage and increase vimentin solubility, which act upstream to facilitate MT1-MMP membrane translocation
Vascular and mesenchymal factors during heart development: a chronological study.
GeneRIF
Mogoantă et al., Craiova, Romania. In Rom J Morphol Embryol, 2011
analysis of CD105, CD31, alpha-SMA, vimentin and desmin expression on a series of normal human heart tissues varying between five and 33 weeks
A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer.
Impact
Camidge et al., Aurora, United States. In J Clin Oncol, 2011
EGFR, KRAS mutation, EGFR fluorescent in situ hybridization and immunohistochemistry, and E-cadherin and vimentin protein levels were also assessed.
More papers using vimentin antibodies
Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma.
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Kalinichenko Vladimir V., In PLoS ONE, 2008
... Antibody for Vimentin was from Cell Signaling Technology (Beverly, MA) ...
Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assembly
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Chen Hong-Chen et al., In The Journal of Cell Biology, 2007
... (H-191), anti-Tks5 (M300), and anti–MT1-MMP (L-15) antibodies, monoclonal anti–β-tubulin (D-10) antibody, and duplex siRNA to vimentin were purchased from Santa Cruz Biotechnology, Inc ...
Statistical meta-analysis with applications.
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Bernhard Eric J., In PLoS ONE, 2007
... The anti-E-cadherin antibody was purchased from BD Transduction Laboratories, anti-vimentin from Santa Cruz Biotechnology, anti- ...
To reg or not to reg: that is the question in COPD.
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Idzko Marco, In PLoS ONE, 2007
... Monoclonal mouse anti-human Cytokeratin 18 (Pierce) and monoclonal mouse anti-human Vimentin (Dako) mAbs were used as ...
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways.
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Lu Zi-Fan et al., In Molecular Vision, 2007
... Primary vimentin antibody was purchased from Epitomics Company (Burlingame, CA) ...
Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis.
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Meurs Eliane F., In PLoS ONE, 2006
... Antibodies (Abs) against IL-15 (L-20), IL-15Rα (sc-9172), IL-2Rβ (sc-1046), IL-2Rγ (sc-670), JAK3 (sc-513), and vimentin (sc-73260) were obtained from Santa Cruz Biotechnology (Delaware, CA) ...
A case of primary small cell carcinoma of the breast
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Bergkvist Leif et al., In Pathology Research International, 2006
... (Dako, clone Ks20.8, 1 : 100), CK7 (Dako, clone OVTL 12/30, 1 : 200), e-cadherin (Dako, clone NCH-38, 1 : 50), vimentin (Dako, clone Vim3B4, 1 : 600), calponin ...
Follicular dendritic cell sarcoma in the lymph nodes of the neck
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Adam Patrick et al., In Diagnostic Pathology, 2006
... VimentinDAKO ...
Antitumor and antimetastatic activities of docetaxel are enhanced by genistein through regulation of osteoprotegerin/receptor activator of nuclear factor-kappaB (RANK)/RANK ligand/MMP-9 signaling in prostate cancer.
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Cicek Muzaffer, In PLoS ONE, 2005
... anti-fibronectin (Santa Cruz), anti-RUNX2 (Santa Cruz), anti-osteopontin (Santa Cruz), anti-periostin (Santa Cruz), anti-E-cadherin (Santa Cruz), anti-vimentin (Dako), anti-RANKL (R&D, Danvers, MA), ...
Luteinising hormone-releasing hormone analogue reverses the cell adhesion profile of EGFR overexpressing DU-145 human prostate carcinoma subline
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Wells A et al., In British Journal of Cancer, 2004
... -catenin, p120 (BD Biosciences, San Jose, CA, USA) and vimentin (Dako Laboratories, Carpinteria, CA, USA) ...
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
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Borthwick Lee A. et al., In The American Journal of Pathology, 2004
... UK), fibronectin (F3648; Sigma-Aldrich, Poole, UK), cytokeratin-19 (sc-6278; Santa Cruz Biotechnology, Inc., Santa Cruz, CA), vimentin (sc-6260; Santa Cruz Biotechnology) and β-actin (a2228; Sigma-Aldrich) ...
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial–mesenchymal transition
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Landberg G et al., In British Journal of Cancer, 2003
... E-cadherin (1:500, clone 4A2C7; Zymed Laboratories, Invitrogen immunodetection, San Francisco, CA, USA), mouse monoclonal anti-human vimentin (1:250, clone V9; Dako, Glostrup, Denmark) antibody and ...
GADD34-PP1c recruited by Smad7 dephosphorylates TGF type I receptor.
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Goumans Marie Jose, In PLoS ONE, 2003
... Anti-Txnip antibody and Anti-Vimentin were from MBL. Anti-E-Cadherin antibody was from ...
NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
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Hong Seong-Doo et al., In Journal of Experimental & Clinical Cancer Research : CR, 2003
... Vimentin was obtained from BD Biosciences (Franklin Lakes, NJ) ...
Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy.
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Gartel Andrei L., In PLoS ONE, 2002
... against versican V1 isoform, Glycogen synthase kinase-3β serine-9 phosphorylation (GSK-3β, S9P), and monoclonal antibody against vimentin were obtained from Abcam.
Direct evidence for a role of β-catenin/LEF-1 signaling pathway in induction of EMT
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Kim Dong-Gyu et al., In Journal of Korean Medical Science, 2001
... antibodies against E-cadherin (R&D systems, Minneapolis, MN, U.S.A.), pancytokeratin (Sigma Aldrich, Saint Louis, MO, U.S.A.), vimentin (Sigma Aldrich, Saint Louis, U.S.A.), and ...
Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells.
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Ryffel Bernhard, In PLoS ONE, 2000
... human albumin (AL-01, mouse, Exbio, Vestec, Czech Republic), human cytokeratin-Alexa Fluor 488 (pan-reactive, Exbio), human vimentin-Dy-547 (Exbio), bovine vitronectin (rabbit, Acris ...
Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia
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Lian QingQuan et al., In Mediators of Inflammation, 1999
... Anti-CD31, anti-Vimentin and anti-COX-2 were purchased from Abcam.
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.
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Chatziantoniou Christos, In PLoS ONE, 1999
... Anti-E-cadherin, anti-α-SMA, anti-vimentin, anti-CK and anti-TGF-β1 antibodies were purchased from Santa Cruz Biotechnology, Inc ...
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
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Paul Marinus A. et al., In Pathology Research International, 1998
... (Novocastra), chromogranin, synaptophysin, calretinin, thrombomodulin, D2-40, CD31, CD34, Factor VIII, E-cadherin, Mib-1, thyroglobulin, P53, S100, vimentin (VUmc), and CDD99 (all from Dako if not otherwise indicated) ...
In vitro analysis of the origin and maintenance of O-2A adult progenitor cells
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Raff Martin C. et al., In The Journal of Cell Biology, 1991
... ); goat antiserum against vimentin (Santa Cruz Biotechnology); monoclonal anti-rat nestin (rat ...
Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons.
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Mei Lin, In PLoS ONE, 1987
... , Dynein intermediate chain (MAB 1618, Chemicon), actin (C4, MAB1501, Chemicon), Vimentin (Abcam, Chemicon), Peripherin (Chemicon), FAK ...
Intracellular free calcium concentration measured with 19F NMR spectroscopy in intact ferret hearts
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Mizuhashi Fukutaro et al., In Journal of Toxicologic Pathology, 1986
... by the labeled streptavidin-biotin method with several antibodies, including anti-porcine vimentin antibody (Dako A/S, Glustrup, Denmark), α-smooth ...
The ferret (Mustela putorius furo L.) as a laboratory animal
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Son Hwa-Young et al., In Laboratory Animal Research, 1970
... sections were covered with 10% goat normal serum for 30 min and incubated overnight with anti-vimentin (1:200, Dako, Glostrup, Denmark) and S-100 ...
Observations on the giant cells of the chinchilla placenta
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Miglino Maria Angelica et al., In Reproductive Biology and Endocrinology, 1960
... antibody against cytokeratin (1:500; PU071-UP, Biogenex, San Ramon, California, U.S.A.) or a goat polyclonal antibody against vimentin (1:500; SC -1226, Santa Cruz Biotechnology, Santa Cruz, California, U.S.A.) ...
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