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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 21 May 2016.

Vimentin

vimentin
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009] (from NCBI)
Top mentioned proteins: E-cadherin, Actin, CAN, HAD, V1a
Papers using vimentin antibodies
Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns.
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Bogyo Matthew, In PLoS ONE, 2010
... The monoclonal antibody for E-cadherin was from BD Pharmingen (Burlington, ON), the monoclonal antibody for vimentin was from Dako (clone 3B4, Burlington, ON), ...
An orally available small molecule inhibitor of c-Met, PF-2341066, reduces tumor burden in a pre-clinical model of ovarian cancer metastasis.
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Lengyel E et al., In Oncogene, 2009
... Louis, MO), Ki-67 antibody from LabVision (Fremont, CA), vimentin, collagen IV and laminin antibodies were from Dako Cytomation (Carpinteria, CA) ...
The role of caveolin-1 in prostate cancer: clinical implications
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Hong Wanjin, In PLoS ONE, 2009
... Antibodies to E-cadherin and vimentin were from Cell Signaling Technology ...
Methylation-dependent binding of the Epstein–Barr virus BZLF1 protein to viral promoters
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Mallet François et al., In DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes, 2008
... It was found that 98% of the cells were vimentin positive and also positive for a monoclonal antibody against specific fibroblast antigen (clone ASO2, Dianova, Hamburg, Germany) ...
Polymerase chain reaction detection of Trypanosoma cruzi in Macaca fascicularis using archived tissues.
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Rodriguez Ana, In PLoS Neglected Tropical Diseases, 2008
... Anti-fd bacteriophage antibody (Sigma Aldrich), recombinant cytokeratin 18, cytokeratin 8, cytokeratin 20 and vimentin were commercially obtained (Cell Sciences).
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Papers on vimentin
Abelmoschus esculentus fractions potently inhibited the pathogenic targets associated with diabetic renal epithelial to mesenchymal transition.
New
Ker et al., Taiwan. In Food Funct, Feb 2016
Our recent studies have focused on diabetic renal epithelial to mesenchymal transition (EMT), which plays a critical role in fibrosis that accompanies increasing vimentin and suggested signals DPP-4/AT-1/TGF-β1.
Protective effect of Ac-SDKP on alveolar epithelial cells through inhibition of EMT via TGF-β1/ROCK1 pathway in silicosis in rat.
New
Yang et al., Tangshan, China. In Toxicol Appl Pharmacol, Feb 2016
Western blot analysis was used to examine for changes in the protein levels of E-cadherin (E-cad) and SP-A (epithelial cell markers), vimentin (mesenchymal cell marker), α-SMA (active myofibroblast marker), and collagen I and III in both in vivo and in vitro experiments.
Clinical impacts of a micropapillary pattern in lung adenocarcinoma: a review.
Review
New
Yuan et al., Hangzhou, China. In Onco Targets Ther, Dec 2015
Molecular markers, including vimentin, napsin A, phosphorylated c-Met, cytoplasmic maspin, Notch-1, MUC1, and tumoral CD10, may have higher expression in MPPAC than other subtypes; conversely, markers such as MUC4 and surfactant apoprotein A have lower expression in MPPAC.
ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.
New
Haura et al., Kitakyūshū, Japan. In Plos One, Dec 2015
Furthermore, numerous ZEB1 responsive genes, such as CDH1 (E-cadherin), ST14, and vimentin, were coordinately regulated along with increased ZEB1 in HCC4006ER cells.
Dermatofibrosarcoma protuberans with pit-like lesions: A case report and literature review.
New
Xiao et al., Xi'an, China. In Oncol Lett, Dec 2015
Immunohistochemical studies revealed positive staining for cluster of differentiation 34, vimentin and lysozyme, which could be used as diagnostic markers of DFSP.
Early changes in blood-based joint tissue destruction biomarkers are predictive of response to tocilizumab in the LITHE study.
New
Karsdal et al., Denmark. In Arthritis Res Ther, Dec 2015
METHOD: Serum biomarkers (CRPM, VICM, C1M, C2M, C3M (MMP-degraded CRP, vimentin type I, II and III collagen), CTX-I/OC (bone turnover), and CRP) were measured in 740 RA patients (the LITHE study) treated with Placebo, or 4 or 8 mg/kg TCZ.
Lipid droplets and steroidogenic cells.
Review
New
Kraemer et al., Stanford, United States. In Exp Cell Res, Dec 2015
Through the interaction of HSL with vimentin and StAR, FC is translocated to mitochondria for steroid hormone production.
Thyroid-like follicular carcinoma of the kidney: one case report and review of the literature.
Review
New
Nodit et al., Pittsburgh, United States. In Am J Clin Pathol, Nov 2015
The tumor cells strongly expressed CK7, PAX-8, PAX-2, vimentin, EMA, and CK19 immunostains.
A Review of the Literature on Primary Leiomyosarcoma of the Prostate Gland.
Review
Venyo, Manchester, United Kingdom. In Adv Urol, 2014
Immunohistochemical staining tends to be positive for vimentin, CD44, smooth muscle actin, and calponin, focally positive for desmin, and at times positive for keratin.
Altered Traffic of Cardiolipin during Apoptosis: Exposure on the Cell Surface as a Trigger for "Antiphospholipid Antibodies".
Review
Sorice et al., Roma, Italy. In J Immunol Res, 2014
In addition, CL association with cytoskeleton protein vimentin was observed.
Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy.
Impact
Weitz et al., Cambridge, United States. In Cell, 2014
We further demonstrate that vimentin acts globally to anchor organelles against randomly fluctuating forces in the cytoplasm, with no effect on their magnitude.
Post-translational modifications of intermediate filament proteins: mechanisms and functions.
Review
Impact
Omary et al., Ann Arbor, United States. In Nat Rev Mol Cell Biol, 2014
IFs, including nuclear lamins and those in the cytoplasm (keratins, vimentin, desmin, neurofilaments and glial fibrillary acidic protein, among others), are functionally regulated by post-translational modifications (PTMs).
Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non-small-cell lung cancer.
Impact
Farace et al., Villejuif, France. In J Clin Oncol, 2013
ALK-rearranged CTCs and tumor specimens were characterized for epithelial (cytokeratins, E-cadherin) and mesenchymal (vimentin, N-cadherin) marker expression.
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation.
Impact
Levine et al., Dallas, United States. In Science, 2012
Akt-mediated phosphorylation of Beclin 1 enhanced its interactions with 14-3-3 and vimentin intermediate filament proteins, and vimentin depletion increased autophagy and inhibited Akt-driven transformation.
Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly.
GeneRIF
Strelkov et al., Leuven, Belgium. In Proc Natl Acad Sci U S A, 2012
analysis of atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
GeneRIF
Hunt et al., Davis, United States. In J Biol Chem, 2012
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
Ablation of vimentin results in defective steroidogenesis.
GeneRIF
Kraemer et al., Palo Alto, United States. In Endocrinology, 2012
vimentin ablation results in defective steroidogenesis
Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation.
GeneRIF
Bayless et al., College Station, United States. In Angiogenesis, 2012
pro-angiogenic signals converge to activate calpain-dependent vimentin cleavage and increase vimentin solubility, which act upstream to facilitate MT1-MMP membrane translocation
Vascular and mesenchymal factors during heart development: a chronological study.
GeneRIF
Mogoantă et al., Craiova, Romania. In Rom J Morphol Embryol, 2011
analysis of CD105, CD31, alpha-SMA, vimentin and desmin expression on a series of normal human heart tissues varying between five and 33 weeks
A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer.
Impact
Camidge et al., Aurora, United States. In J Clin Oncol, 2011
EGFR, KRAS mutation, EGFR fluorescent in situ hybridization and immunohistochemistry, and E-cadherin and vimentin protein levels were also assessed.
More papers using vimentin antibodies
Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma.
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Kalinichenko Vladimir V., In PLoS ONE, 2008
... Antibody for Vimentin was from Cell Signaling Technology (Beverly, MA) ...
Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assembly
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Chen Hong-Chen et al., In The Journal of Cell Biology, 2007
... (H-191), anti-Tks5 (M300), and anti–MT1-MMP (L-15) antibodies, monoclonal anti–β-tubulin (D-10) antibody, and duplex siRNA to vimentin were purchased from Santa Cruz Biotechnology, Inc ...
Statistical meta-analysis with applications.
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Bernhard Eric J., In PLoS ONE, 2007
... The anti-E-cadherin antibody was purchased from BD Transduction Laboratories, anti-vimentin from Santa Cruz Biotechnology, anti- ...
To reg or not to reg: that is the question in COPD.
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Idzko Marco, In PLoS ONE, 2007
... Monoclonal mouse anti-human Cytokeratin 18 (Pierce) and monoclonal mouse anti-human Vimentin (Dako) mAbs were used as ...
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways.
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Lu Zi-Fan et al., In Molecular Vision, 2007
... Primary vimentin antibody was purchased from Epitomics Company (Burlingame, CA) ...
Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis.
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Meurs Eliane F., In PLoS ONE, 2006
... Antibodies (Abs) against IL-15 (L-20), IL-15Rα (sc-9172), IL-2Rβ (sc-1046), IL-2Rγ (sc-670), JAK3 (sc-513), and vimentin (sc-73260) were obtained from Santa Cruz Biotechnology (Delaware, CA) ...
A case of primary small cell carcinoma of the breast
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Bergkvist Leif et al., In Pathology Research International, 2006
... (Dako, clone Ks20.8, 1 : 100), CK7 (Dako, clone OVTL 12/30, 1 : 200), e-cadherin (Dako, clone NCH-38, 1 : 50), vimentin (Dako, clone Vim3B4, 1 : 600), calponin ...
Follicular dendritic cell sarcoma in the lymph nodes of the neck
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Adam Patrick et al., In Diagnostic Pathology, 2006
... VimentinDAKO ...
Antitumor and antimetastatic activities of docetaxel are enhanced by genistein through regulation of osteoprotegerin/receptor activator of nuclear factor-kappaB (RANK)/RANK ligand/MMP-9 signaling in prostate cancer.
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Cicek Muzaffer, In PLoS ONE, 2005
... anti-fibronectin (Santa Cruz), anti-RUNX2 (Santa Cruz), anti-osteopontin (Santa Cruz), anti-periostin (Santa Cruz), anti-E-cadherin (Santa Cruz), anti-vimentin (Dako), anti-RANKL (R&D, Danvers, MA), ...
Luteinising hormone-releasing hormone analogue reverses the cell adhesion profile of EGFR overexpressing DU-145 human prostate carcinoma subline
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Wells A et al., In British Journal of Cancer, 2004
... -catenin, p120 (BD Biosciences, San Jose, CA, USA) and vimentin (Dako Laboratories, Carpinteria, CA, USA) ...
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
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Borthwick Lee A. et al., In The American Journal of Pathology, 2004
... UK), fibronectin (F3648; Sigma-Aldrich, Poole, UK), cytokeratin-19 (sc-6278; Santa Cruz Biotechnology, Inc., Santa Cruz, CA), vimentin (sc-6260; Santa Cruz Biotechnology) and β-actin (a2228; Sigma-Aldrich) ...
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial–mesenchymal transition
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Landberg G et al., In British Journal of Cancer, 2003
... E-cadherin (1:500, clone 4A2C7; Zymed Laboratories, Invitrogen immunodetection, San Francisco, CA, USA), mouse monoclonal anti-human vimentin (1:250, clone V9; Dako, Glostrup, Denmark) antibody and ...
GADD34-PP1c recruited by Smad7 dephosphorylates TGF type I receptor.
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Goumans Marie Jose, In PLoS ONE, 2003
... Anti-Txnip antibody and Anti-Vimentin were from MBL. Anti-E-Cadherin antibody was from ...
NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
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Hong Seong-Doo et al., In Journal of Experimental & Clinical Cancer Research : CR, 2003
... Vimentin was obtained from BD Biosciences (Franklin Lakes, NJ) ...
Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy.
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Gartel Andrei L., In PLoS ONE, 2002
... against versican V1 isoform, Glycogen synthase kinase-3β serine-9 phosphorylation (GSK-3β, S9P), and monoclonal antibody against vimentin were obtained from Abcam.
Direct evidence for a role of β-catenin/LEF-1 signaling pathway in induction of EMT
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Kim Dong-Gyu et al., In Journal of Korean Medical Science, 2001
... antibodies against E-cadherin (R&D systems, Minneapolis, MN, U.S.A.), pancytokeratin (Sigma Aldrich, Saint Louis, MO, U.S.A.), vimentin (Sigma Aldrich, Saint Louis, U.S.A.), and ...
Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells.
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Ryffel Bernhard, In PLoS ONE, 2000
... human albumin (AL-01, mouse, Exbio, Vestec, Czech Republic), human cytokeratin-Alexa Fluor 488 (pan-reactive, Exbio), human vimentin-Dy-547 (Exbio), bovine vitronectin (rabbit, Acris ...
Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia
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Lian QingQuan et al., In Mediators of Inflammation, 1999
... Anti-CD31, anti-Vimentin and anti-COX-2 were purchased from Abcam.
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.
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Chatziantoniou Christos, In PLoS ONE, 1999
... Anti-E-cadherin, anti-α-SMA, anti-vimentin, anti-CK and anti-TGF-β1 antibodies were purchased from Santa Cruz Biotechnology, Inc ...
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
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Paul Marinus A. et al., In Pathology Research International, 1998
... (Novocastra), chromogranin, synaptophysin, calretinin, thrombomodulin, D2-40, CD31, CD34, Factor VIII, E-cadherin, Mib-1, thyroglobulin, P53, S100, vimentin (VUmc), and CDD99 (all from Dako if not otherwise indicated) ...
In vitro analysis of the origin and maintenance of O-2A adult progenitor cells
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Raff Martin C. et al., In The Journal of Cell Biology, 1991
... ); goat antiserum against vimentin (Santa Cruz Biotechnology); monoclonal anti-rat nestin (rat ...
Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons.
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Mei Lin, In PLoS ONE, 1987
... , Dynein intermediate chain (MAB 1618, Chemicon), actin (C4, MAB1501, Chemicon), Vimentin (Abcam, Chemicon), Peripherin (Chemicon), FAK ...
Intracellular free calcium concentration measured with 19F NMR spectroscopy in intact ferret hearts
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Mizuhashi Fukutaro et al., In Journal of Toxicologic Pathology, 1986
... by the labeled streptavidin-biotin method with several antibodies, including anti-porcine vimentin antibody (Dako A/S, Glustrup, Denmark), α-smooth ...
The ferret (Mustela putorius furo L.) as a laboratory animal
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Son Hwa-Young et al., In Laboratory Animal Research, 1970
... sections were covered with 10% goat normal serum for 30 min and incubated overnight with anti-vimentin (1:200, Dako, Glostrup, Denmark) and S-100 ...
Observations on the giant cells of the chinchilla placenta
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Miglino Maria Angelica et al., In Reproductive Biology and Endocrinology, 1960
... antibody against cytokeratin (1:500; PU071-UP, Biogenex, San Ramon, California, U.S.A.) or a goat polyclonal antibody against vimentin (1:500; SC -1226, Santa Cruz Biotechnology, Santa Cruz, California, U.S.A.) ...
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