gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Hippocalcin-like 1

VILIP-3, NVL-3, HPCAL1, visinin-like protein 3, NVP-3
plays a role in neuronal calcium sensing [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: VILIP-1, NVP2, CIs, CsF, ACID
Papers on VILIP-3
Proteome-wide identification of novel ceramide-binding proteins by yeast surface cDNA display and deep sequencing.
New
Liu et al., United States. In Mol Cell Proteomics, Feb 2016
Interestingly, four of the verified ceramide-binding proteins (HPCA, HPCAL1, NCS1, and VSNL1) and an additional three candidate ceramide-binding proteins (NCALD, HPCAL4, and KCNIP3) belong to the neuronal calcium sensor (NCS) family of EF hand-containing proteins.
Hippocalcin-like 1 suppresses hepatocellular carcinoma progression by promoting p21(Waf/Cip1) stabilization via activating ERK1/2-MAPK pathway.
New
Liu et al., Shanghai, China. In Hepatology, Jan 2016
Hippocalcin-like 1(HPCAL1) is found as a calcium sensor protein.
Genome-wide association study of kidney function decline in individuals of European descent.
New
Böger et al., Regensburg, Germany. In Kidney Int, May 2015
In stage 1 GWAS meta-analysis, single-nucleotide polymorphisms (SNPs) at MEOX2, GALNT11, IL1RAP, NPPA, HPCAL1, and CDH23 showed the strongest associations for at least one trait, in addition to the known UMOD locus, which showed genome-wide significance with an annual change in eGFR.
Specific interaction to PIP2 increases the kinetic rate of membrane binding of VILIPs, a subfamily of Neuronal Calcium Sensors (NCS) proteins.
Girard-Egrot et al., Villeurbanne, France. In Biochim Biophys Acta, 2014
The interaction of two members of this family, VILIP-1 and VILIP-3, with Langmuir monolayers as membrane models has been investigated in order to study the effects of both myristoylation and the highly basic region containing conserved poly-lysine residues on membrane association kinetics and binding properties.
Mutations that disrupt PHOXB interaction with the neuronal calcium sensor HPCAL1 impede cellular differentiation in neuroblastoma.
George et al., Boston, United States. In Oncogene, 2014
The neuronal calcium sensor protein HPCAL1 (VILIP-3) exhibited strong binding to WT PHOX2B and a CCHS-associated polyalanine expansion mutant but only weakly or not at all to neuroblastoma-associated frameshift and truncation variants.
Identification of risk genes for autism spectrum disorder through copy number variation analysis in Austrian families.
Vincent et al., Toronto, Canada. In Neurogenetics, 2014
Twenty-two CNVs were validated from this set (five of which are apparently de novo), many of which appear likely to disrupt genes that may be considered as good candidates for neuropsychiatric disorders, including DLG2, S100B, ARX, DIP2A, HPCAL1, and GPHN.
Development and characterization of monoclonal antibodies against pancreatic cancer marker hippocalcin-like 1 protein.
Cao et al., Wuxi, China. In Monoclon Antib Immunodiagn Immunother, 2014
The hippocalcin-like 1 protein (HPCAL1) is expressed in most pancreatic cancer cell lines.
Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers.
Girard-Egrot et al., Villeurbanne, France. In Plos One, 2013
The neuronal calcium sensor proteins Visinin-like Proteins 1 (VILIP-1) and 3 (VILIP-3) are effectors of guanylyl cyclase and acetyl choline receptors, and transduce calcium signals in the brain.
The EHEC-host interactome reveals novel targets for the translocated intimin receptor.
Koegl et al., Heidelberg, Germany. In Sci Rep, 2013
Notably, the conserved interactions included those of serine/threonine kinase 16 (STK16), hippocalcin-like 1 (HPCAL1) as well as neurocalcin-delta (NCALD).
Technical note: identification of reference genes for gene expression studies in different bovine tissues focusing on different fat depots.
Mielenz et al., Bonn, Germany. In J Dairy Sci, 2012
The 3 most stable REF in individual fat tissues and muscle were EMD (emerin), POLR2A (RNA polymerase II), and LRP10 (lipoprotein receptor-related protein 10); in mammary gland were MARVELD1 (marvel domain containing 1), EMD, and LRP10; and in liver were HPCAL1 (hippocalcin-like 1), LRP10, and EIF3K (Eukaryotic translation initiation factor 3).
The visinin-like proteins VILIP-1 and VILIP-3 in Alzheimer's disease-old wine in new bottles.
Braunewell, Birmingham, United States. In Front Mol Neurosci, 2012
Genome-wide association studies (GWAS) show association of genetic variants of VILIP-1 (VSNL1) and VILIP-3 (HPCAL1) with AD+P (+psychosis) and late onset AD (LOAD), respectively.
Development and optimization of an antibody array method for potential cancer biomarker detection.
Cao et al., Nanjing, China. In J Biomed Res, 2011
The aim of the present study was to optimize the conditions of antibody arrays for detecting Hippocalcin-like 1 (HPCAL1), phosphatidylethanolamine binding protein 1 (PEBP1), lectin galactoside-binding soluble 7 (LGALS7), and serpin peptidase inhibitor clade E member 2 (SERPINE2) as biomarkers for pancreatic cancer detection in a single assay and to investigate antibodies' specificity and cross-reactivity.
Putative reference genes for gene expression studies in propionate and β-hydroxybutyrate treated bovine adipose tissue explants.
Mielenz et al., Bonn, Germany. In J Anim Physiol Anim Nutr (berl), 2010
geNorm™ and Normfinder(©) estimated the most stable RGs in the following sequence for subcutaneous and for retroperitoneal AT explants treated with propionate: low density lipoprotein receptor-related protein 10 (LRP10) > hippocalcin-like 1 (HPCAL1) > glyceraldehyde-phosphate-dehydrogenase (GAPDH) > ribosomal protein S9 (RPS9) > RNA polymerase II (Pol II) > beta2 actin (ACTB) > 18S ribosomal RNA (18S rRNA).
Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+ -sensor proteins.
Review
Szanto et al., Birmingham, United States. In Cell Tissue Res, 2009
The visinin-like protein (VSNL) subfamily, including VILIP-1 (the founder protein), VILIP-2, VILIP-3, hippocalcin, and neurocalcin delta, constitute a highly homologous subfamily of neuronal calcium sensor (NCS) proteins.
Functional contribution of Ca2+ and Mg2+ to the intermolecular interaction of visinin-like proteins.
GeneRIF
Chang et al., Kao-hsiung, Taiwan. In Protein J, 2006
The interaction of human VILIP1 and VILIP3 with divalent cations was explored using circular dichroism and fluorescence measurement.
Neuronal calcium sensor protein visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner.
GeneRIF
Tateno et al., Asahikawa, Japan. In J Biol Chem, 2004
visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner
Calcium-myristoyl switch, subcellular localization, and calcium-dependent translocation of the neuronal calcium sensor protein VILIP-3, and comparison with VILIP-1 in hippocampal neurons.
GeneRIF
Braunewell et al., Berlin, Germany. In Mol Cell Neurosci, 2003
direct comparison of the localization and calcium-dependent translocation of visinin-like-proteins 1 and 3 in hippocampal neurons
Evidence for different functional properties of the neuronal calcium sensor proteins VILIP-1 and VILIP-3: from subcellular localization to cellular function.
GeneRIF
Braunewell et al., Germany. In Biochim Biophys Acta, 2002
Evidence for different functional properties of NVP-1 and NVP-3: from subcellular localization to cellular function.
Abnormal localization of two neuronal calcium sensor proteins, visinin-like proteins (vilips)-1 and -3, in neocortical brain areas of Alzheimer disease patients.
GeneRIF
Bernstein et al., Magdeburg, Germany. In Dement Geriatr Cogn Disord, 2001
VILIP-3 immunostaining was found to be reduced in Alzheimer brains; immunoreactive material was detected in close association with amyloid plaques and neurofibrillar tangles, typical pathologic hallmarks of AD
Constitutive expression of C-myc in nih 3t3 cells which coexpress the colony stimulating factor-I receptor and the catalytic domain of the gtpase-activating protein restores colony stimulating factor-I dependent mitogenic growth.
Ostrowski et al., Durham, United States. In Int J Oncol, 1992
We find that modulation of the immediate early gene c-myc and a delayed early response represented by the retrotransposon NVL3 were selectively impaired in both situations.
share on facebooktweetadd +1mail to friends