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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Solute carrier family 17

VGLUT1, vesicular glutamate transporter 1
a Na(+)-dependent inorganic phosphate cotransporter; may be involved in neuronal Na+ transport [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: ACID, Rdl, CAN, VGAT, Synaptophysin
Papers using VGLUT1 antibodies
Real-time PCR for mRNA quantitation
Supplier
Thinakaran Gopal et al., In Molecular Neurodegeneration, 2004
... Double immunofluorescence analysis of calbindin and VGLUT1 or VGLUT-2 labeling in cerebellum of non-transgenic animals ...
Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons
Supplier
Chapman Edwin R. et al., In The Journal of Cell Biology, 2003
... (BD Biosciences), mouse monoclonal anti–SNAP-25-C (Research & Diagnostic Antibodies), rabbit polyclonal antisynapsin and guinea pig anti–vesicular glutamate transporter 1 (Chemicon), chicken polyclonal anti-GFP (Abcam), and mouse monoclonal anti-FLAG ...
Autolytic transition of mu-calpain upon activation as resolved by antibodies distinguishing between the pre- and post-autolysis forms.
Supplier
Okazawa Hitoshi, In PLoS ONE, 1991
... rabbit anti-Satb2 (1∶1000, Abcam, Cambridge, UK), rat anti-Ctip2 (1∶500, Abcam), rabbit anti-Tbr1 (1∶500, Abcam), rabbit anti-vGlut1 (1∶1000, Synaptic Systems, Göttingen, Germany), rabbit anti-Foxg1 ...
Papers on VGLUT1
Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult.
New
Shore et al., United States. In Neuroscience, Mar 2016
Vesicular glutamate transporters 1 and 2 (VGLUT1 and VGLUT2) have distinct distributions in the cochlear nucleus that correspond to sources of the labeled terminals.
DGKθ Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses.
New
Raben et al., Baltimore, United States. In Cell Rep, Feb 2016
Using synaptophysin- and vGlut1-pHluorin optical reporters, we found that acute and chronic deletion of DGKθ attenuated the recovery of SVs following neuronal stimulation.
Lipoic acid improves neuronal insulin signalling and rescues cognitive function regulating VGlut1 expression in high-fat-fed rats: Implications for Alzheimer's disease.
New
Ramirez et al., Pamplona, Spain. In Biochim Biophys Acta, Feb 2016
Moreover, some lines of evidence indicated that VGlut1 is impaired in frontal regions of AD patients and this impairment is correlated with the progression of cognitive decline in AD.
Possible contribution of epigenetic changes in the development of schizophrenia-like behavior in vasopressin-deficient Brattleboro rats.
New
Zelena et al., Budapest, Hungary. In Behav Brain Res, Jan 2016
DNA methyltransferase1 (DNMT1), DNMT3a, as well as COMT, GAD, VGLUT1, 5HT2A, BDNF mRNA levels in prefrontal brain region and hippocampus were studied by qRT-PCR.
Structural Changes and Lack of HCN1 Channels in the Binaural Auditory Brainstem of the Naked Mole-Rat (Heterocephalus glaber).
New
Koch et al., Berlin, Germany. In Plos One, Dec 2015
Using antibody stainings against excitatory and inhibitory presynaptic structures, namely the vesicular glutamate transporter VGluT1 and the glycine transporter GlyT2 we identified all major auditory brainstem nuclei except the superior paraolivary nucleus in these animals.
Effects of Fluoxetine and Visual Experience on Glutamatergic and GABAergic Synaptic Proteins in Adult Rat Visual Cortex(1,2,3).
New
Murphy et al., Hamilton, Canada. In Eneuro, Nov 2015
To test this we studied the effect of fluoxetine treatment in adult rats, alone or in combination with visual deprivation [monocular deprivation (MD)], on a set of highly conserved presynaptic and postsynaptic proteins (synapsin, synaptophysin, VGLUT1, VGAT, PSD-95, gephyrin, GluN1, GluA2, GluN2B, GluN2A, GABAAα1, GABAAα3).
Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?
Review
Smolders et al., Brussels, Belgium. In Front Cell Neurosci, 2012
We will first describe the current knowledge on vesicular glutamate transporters (VGLUT1/2/3), the vesicular excitatory amino acid transporter (VEAT), the vesicular nucleotide transporter (VNUT), vesicular monoamine transporters (VMAT1/2), the vesicular acetylcholine transporter (VAChT) and the vesicular γ-aminobutyric acid (GABA) transporter (VGAT) in the brain.
[Genetics and epigenetics of schizophrenia].
Review
Celli et al., Roma, Italy. In Clin Ter, 2012
Researches in molecular biology field have allowed the identification of genes that confer susceptibility to schizophrenia on chromosomes 1, 2, 3, 5, 6, 8, 10, 11, 13, 14, 20 and 22. Epigenetic modifications of gene expression, that not involve the primary DNA sequence, may also predispose to schizophrenia, in particular the methylation of genes involved in neurotransmission (RELN, GAD1, MARLIN-1, and NR3B GRIA2, VGLUT1 and 2, 5HT2a, COMT and BDNF), the histone modifications and the action of non-coding RNAs.
Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons.
GeneRIF
Liposits et al., Budapest, Hungary. In Endocrinology, 2012
Data indicate that GABAergic axons were labeled with vesicular inhibitory aa transporter (VIAAT) antibodies, whereas glutamatergic axons were detected with antisera against the major vesicular glutamate transporter (VGLUT) isoforms, VGLUT1 and VGLUT2.
Sensorimotor gating, working and social memory deficits in mice with reduced expression of the vesicular glutamate transporter VGLUT1.
GeneRIF
Gass et al., Mannheim, Germany. In Behav Brain Res, 2012
This study indicated that VGLUT1 may play an important role in some abnormalities associated with schizophrenia, particularly cognitive deficits
VGLUT1 is localized in astrocytic processes in several brain regions.
GeneRIF
Gundersen et al., Oslo, Norway. In Glia, 2012
VGLUT1 labeling is concentrated in astrocytic processes from wild type, and not in VGLUT1 knockout hippocampus.
Vesicular glutamate transporter immunoreactivity in the periodontal ligament of the rat incisor.
GeneRIF
Wakisaka et al., Ōsaka, Japan. In Anat Rec (hoboken), 2012
VGluT1 immunoreactions are localized within the cytoplasm for all sizes of trigeminal neurons, although predominantly in medium-large trigeminal neurons.
In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice.
GeneRIF
Brose et al., Göttingen, Germany. In J Neurosci, 2011
This study provide a detailed analysis of synaptic vesicle sharing in vitro, and show that network homeostasis leads to dynamic scaling of synaptic VGLUT1 levels.
A role for glia in the progression of Rett's syndrome.
Impact
Mandel et al., Portland, United States. In Nature, 2011
Furthermore, restoration of MeCP2 in the mutant astrocytes exerted a non-cell-autonomous positive effect on mutant neurons in vivo, restoring normal dendritic morphology and increasing levels of the excitatory glutamate transporter VGLUT1.
Glutamatergic drive of the dorsal raphe nucleus.
Review
Commons et al., Boston, United States. In J Chem Neuroanat, 2011
Within the DR, glutamate-containing axon terminals can be identified by their content of one of three types of vesicular glutamate transporter, VGLUT1, 2 or 3.
From glutamate co-release to vesicular synergy: vesicular glutamate transporters.
Review
Impact
Trudeau et al., Paris, France. In Nat Rev Neurosci, 2011
This notion has been strengthened by the demonstration that three vesicular glutamate transporters (vesicular glutamate transporter 1 (VGLUT1), VGLUT2 and VGLUT3) are present in central monoamine, acetylcholine and GABA neurons, as well as in primarily glutamatergic neurons.
VGLUT1 and VGLUT2 mRNA expression in the primate auditory pathway.
Review
Balaram et al., Nashville, United States. In Hear Res, 2011
These patterns imply that VGLUT2 is the main vesicular glutamate transporter in subcortical and thalamocortical (TC) circuits, whereas VGLUT1 is dominant in corticocortical (CC) and corticothalamic (CT) systems of projections.
Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites.
Impact
GeneRIF
Edwards et al., San Francisco, United States. In Science, 2004
developing hippocampal neurons transiently coexpressed VGLUT2 and VGLUT1 at distinct synaptic sites with different short-term plasticity; the loss of VGLUT1 reduced the reserve pool of synaptic vesicles [vglut1]
Neurobiology. Long-sought protein packages glutamate.
Impact
Helmuth, In Science, 2000
On page 957, researchers report that they've found this elusive transporter, dubbed VGLUT1.
Uptake of glutamate into synaptic vesicles by an inorganic phosphate transporter.
Impact
Edwards et al., San Francisco, United States. In Science, 2000
In addition, we show that this vesicular glutamate transporter, VGLUT1, exhibits a conductance for chloride that is blocked by glutamate.
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