ARL4, an ARF-like Protein That Is Developmentally Regulated and Localized to Nuclei and Nucleoli
In PLoS ONE, 1999
... ATPase, Bax (Santa Cruz Biotechnology, Santa Cruz, CA, USA), VDAC (Cell Signaling Technology, Danvers, MA, USA), ...
Polyphenols as mitochondria-targeted anticancer drugs.
Łódź, Poland. In Cancer Lett, 01 Nov 2015
(2013) according to their molecular mode of action into: hexokinase inhibitors; mimickers of the Bcl-2 homology-3 (BH3) domains; thiol redox inhibitors; deregulators of voltage-dependent anionic channel (VDAC)/adenine nucleotide translocase (ANT) complex; electron redox chain-targeting agents; lipophilic cations targeting the mitochondrial inner membrane; tricarboxylic acid cycle-targeting agents; and mitochondrial DNA-targeting agents.
The mitochondrial voltage-dependent anion channel 1 in tumor cells.
Beersheba, Israel. In Biochim Biophys Acta, 31 Oct 2015
In addressing the recently solved 3D structures of VDAC1, this review will point to structure-function relationships of VDAC as critical for deciphering how this channel can perform such a variety of roles, all of which are important for cell life and death.
TSPO is a REDOX regulator of cell mitophagy.
London, United Kingdom. In Biochem Soc Trans, Sep 2015
This review focuses on the current understanding of this pathway and focuses on the interplay with reactive oxygen species (ROS) and the voltage-dependent anion channel (VDAC), to which TSPO binds, in the regulation of cell mitophagy and hence homoeostasis of the mitochondrial network as a whole.
Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis.
Montréal, Canada. In Mol Cell Endocrinol, Jul 2015
Steroidogenesis begins with cholesterol transfer into mitochondria through the transduceosome, a complex composed of cytosolic proteins that include steroidogenesis acute regulatory protein (STAR), 14-3-3 adaptor proteins, and the outer mitochondrial membrane proteins Translocator Protein (TSPO) and Voltage-Dependent Anion Channel (VDAC).
[18 kDa translocator protein--implications in cell's functions].
Laizhou, China. In Postepy Hig Med Dosw (online), Dec 2014
TSPO has been shown to interact with other cellular proteins: 32 kDa voltage-dependent anion channel (VDAC), 30 kDa adenine nucleotide translocase (ANT), cyclophilin D, hexokinase, creatinine kinase, diazepam binding inhibitor (DBI), phosphate carrier and Bcl-2 family.