Papers using
V-ATPase
antibodies
Papers on
V-ATPase
Rag GTPase in amino acid signaling.Kim et al., Seoul, South Korea. In Amino Acids, Feb 2016
In this review, we provide a current understanding on the amino acid-regulated cell growth control via Rag-mTORC1 with recently identified key players, including Ragulator, v-ATPase, and GATOR complexes.
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.Fitzgibbon et al., Cambridge, United States. In Nat Genet, Jan 2016
More than half of the mutations preferentially co-occurred with mutations in ATP6V1B2 and ATP6AP1, which encode components of the vacuolar H(+)-ATP ATPase (V-ATPase) known to be necessary for amino acid-induced activation of mTORC1.
Proton Transport and pH Control in Fungi.Kane, Syracuse, United States. In Adv Exp Med Biol, Dec 2015
The activities of Pma1 and the V-ATPase are coordinated under some conditions, suggesting that pH in the cytosol and organelles is not controlled independently.
Recent Insights into the Structure, Regulation, and Function of the V-ATPases.Forgac et al., Boston, United States. In Trends Biochem Sci, Oct 2015
This review focuses on recent insights into their structure and mechanism, the mechanisms that regulate V-ATPase activity (particularly regulated assembly and trafficking), and the role of V-ATPases in processes such as cell signaling and cancer.
Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.Rubinstein et al., Toronto, Canada. In Nature, Jun 2015
The eukaryotic V-ATPase is the most complex rotary ATPase: it has three peripheral stalks, a hetero-oligomeric proton-conducting proteolipid ring, several subunits not found in other rotary ATPases, and is regulated by reversible dissociation of its catalytic and proton-conducting regions.
Metabolism. Differential regulation of mTORC1 by leucine and glutamine.Guan et al., San Diego, United States. In Science, Feb 2015
Amino acids stimulate mTORC1 activation at the lysosome in a manner thought to be dependent on the Rag small guanosine triphosphatases (GTPases), the Ragulator complex, and the vacuolar H(+)-adenosine triphosphatase (v-ATPase).