Isoform-Level Gene Expression Profiles of Human Y Chromosome Azoospermia Factor Genes and Their X Chromosome Paralogs in the Testicular Tissue of Non-Obstructive Azoospermia Patients.
Tehrān, Iran. In J Proteome Res, 04 Oct 2015
We profiled the expression of 41 alternative transcripts encoded by 14 AZFa, AZFb, and AZFc region genes (USP9Y, DDX3Y, XKRY, HSFY1, CYORF15A, CYORF15B, KDM5D, EIF1AY, RPS4Y2, RBMY1A1, PRY, BPY2, DAZ1, and CDY1) as well as their X chromosome homologue transcripts and a few autosomal homologues.
USP10: friend and foe.
Leiden, Netherlands. In Cell, 2010
In this issue, Yuan et al. (2010) identify the deubiquitinating protease USP10 as a new regulator of p53 in the DNA damage response and tumor development.
Spermatogenesis in a man with complete deletion of USP9Y.
Siena, Italy. In N Engl J Med, 2009
Deletions in the azoospermia factor region AZFa on the human Y chromosome and, more specifically, in the region that encompasses the ubiquitin-specific peptidase 9, Y-linked gene USP9Y have been implicated in infertility associated with oligospermia and azoospermia.
Role of the AZFa candidate genes in male infertility.
Padova, Italy. In J Endocrinol Invest, 2000
It contains three genes, USP9Y, DBY and UTY, but only the former two can be at present considered candidate genes for the infertile phenotype associated with deletion of this interval.