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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 25 Jan 2016.

Ubiquitin specific peptidase 9, Y-linked

USP9Y, DFFRY, USP10
This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009] (from NCBI)
Top mentioned proteins: Ubiquitin, MEN, HAD, DAZ, CAN
Papers on USP9Y
Expression and clinical implication of S100A12 in gastric carcinoma.
New
Yuan et al., Wuhan, China. In Tumour Biol, 05 Jan 2016
Moreover, survival analysis was performed and the correlation between S100A12 and ubiquitin-specific protease 10 (USP10) and p53 was determined.
USP10 Expression in Normal Adrenal Gland and Various Adrenal Tumors.
New
Xiong et al., Wuhan, China. In Endocr Pathol, 31 Dec 2015
Ubiquitin-specific protease 10 (USP10), a novel deubiquitinating enzyme, is associated with androgen receptor transcriptional activity and pathological processes of tumor.
Crystal structure of the G3BP2 NTF2-like domain in complex with a canonical FGDF motif peptide.
New
Kristensen, Copenhagen, Denmark. In Biochem Biophys Res Commun, 06 Dec 2015
The most studied binding partners, USP10 and viral nsP3, interfere with essential G3BP functions related to assembly of cellular stress granules.
Isoform-Level Gene Expression Profiles of Human Y Chromosome Azoospermia Factor Genes and Their X Chromosome Paralogs in the Testicular Tissue of Non-Obstructive Azoospermia Patients.
New
Salekdeh et al., Tehrān, Iran. In J Proteome Res, Oct 2015
We profiled the expression of 41 alternative transcripts encoded by 14 AZFa, AZFb, and AZFc region genes (USP9Y, DDX3Y, XKRY, HSFY1, CYORF15A, CYORF15B, KDM5D, EIF1AY, RPS4Y2, RBMY1A1, PRY, BPY2, DAZ1, and CDY1) as well as their X chromosome homologue transcripts and a few autosomal homologues.
DDX3Y, a Male-Specific Region of Y Chromosome Gene, May Modulate Neuronal Differentiation.
New
Salekdeh et al., Tehrān, Iran. In J Proteome Res, Oct 2015
The expression level of 12 Y-linked genes significantly increased over neural differentiation, including RBMY1, EIF1AY, DDX3Y, HSFY1, BPY2, PCDH11Y, UTY, RPS4Y1, USP9Y, SRY, PRY, and ZFY.
Clinical utility of a novel urine-based gene fusion TTTY15-USP9Y in predicting prostate biopsy outcome.
New
Sun et al., Shanghai, China. In Urol Oncol, Sep 2015
Our previous study has demonstrated the high prevalence of TTTY15-USP9Y in prostate cancer samples from a Chinese population.
TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.
New
Wu et al., Nanchang, China. In J Biol Chem, Jun 2015
We found TANK formed a complex with MCPIP1 (also known as ZC3H12A) and a deubiquitinase, USP10, which was essential for the USP10-dependent deubiquitination of TRAF6 and the resolution of genotoxic NF-κB activation upon DNA damage.
High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer.
Ren et al., Hangzhou, China. In Int J Clin Exp Med, 2014
Four high-frequency prostate cancer (CaP) specific fusion genes, SDK1:AMACR, RAD50:PDLIM4, CTAGE5:KHDRBS3 and USP9Y:TTTY15 have been reported in Chinese CaP samples through a transcriptome sequencing study.
A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation.
Tjian et al., United States. In Elife, 2014
We found that Huwe1 activity on TBP is antagonized by the deubiquitinase USP10, which protects TBP from degradation.
DDX3Y gene rescue of a Y chromosome AZFa deletion restores germ cell formation and transcriptional programs.
Reijo Pera et al., Stanford, United States. In Sci Rep, 2014
Deletions of the AZFa region typically encompass two genes: DDX3Y and USP9Y.
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13.
Impact
GeneRIF
Yuan et al., Shanghai, China. In Cell, 2011
USP10 mediates the deubiquitination of p53, regulating deubiquitination activity of USP10 and USP13 by Beclin1 provides a mechanism for Beclin1 to control the levels of p53.
The deubiquitinating enzyme USP10 regulates the endocytic recycling of CFTR in airway epithelial cells.
GeneRIF
Stanton et al., United States. In Channels (austin), 2010
a novel function for USP10 in facilitating the deubiquitination of CFTR in early endosomes, thereby enhancing the endocytic recycling and cell surface expression of CFTR.
USP10 regulates p53 localization and stability by deubiquitinating p53.
Impact
GeneRIF
Lou et al., Rochester, United States. In Cell, 2010
Findings reveal USP10 to be a novel regulator of p53, providing an alternative mechanism of p53 inhibition in cancers with wild-type p53.
USP10: friend and foe.
Impact
Shiloh et al., Leiden, Netherlands. In Cell, 2010
In this issue, Yuan et al. (2010) identify the deubiquitinating protease USP10 as a new regulator of p53 in the DNA damage response and tumor development.
The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells.
GeneRIF
Stanton et al., United States. In J Biol Chem, 2009
USP10 has a role in facilitating the deubiquitination of CFTR in early endosomes and thereby enhancing the endocytic recycling of CFTR
Spermatogenesis in a man with complete deletion of USP9Y.
Impact
Piomboni et al., Siena, Italy. In N Engl J Med, 2009
Deletions in the azoospermia factor region AZFa on the human Y chromosome and, more specifically, in the region that encompasses the ubiquitin-specific peptidase 9, Y-linked gene USP9Y have been implicated in infertility associated with oligospermia and azoospermia.
AZF gene expression analysis in peripheral leukocytes and testicular cells from idiopathic infertility.
GeneRIF
Wu et al., Nanjing, China. In Arch Androl, 2007
Frequency of AZF microdeletions in peripheral leukocytes and testicular cells in Chinese men with idiopathic infertility.
A Y-encoded subunit of the translation initiation factor Eif2 is essential for mouse spermatogenesis.
Impact
Burgoyne et al., London, United Kingdom. In Nat Genet, 2001
4,5), Smcy, Uty, Usp9y (also known as Dffry), Eif2s3y (also known as Eif-2gammay) and Dby10; all have closely similar X-encoded homologs.
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