Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Stanford, United States. In Nature, 2013
Here we show that in Ts65Dn mice, which are trisomic for 132 genes homologous to genes on human chromosome 21, triplication of Usp16 reduces the self-renewal of haematopoietic stem cells and the expansion of mammary epithelial cells, neural progenitors and fibroblasts.
Thyroid hormone-related regulation of gene expression in human fatty liver.
Boston, United States. In J Clin Endocrinol Metab, 2009
This gene set included genes related to RNA metabolism (SNRPE, HNRPH3, TIA1, and SFRS2), protein catabolism (PSMA1, PSMD12, USP9X, IBE2B, USP16, and PCMT1), and energy metabolism (ATP5C1, COX7C, UQCRB).