Unique Aspects of Plant Nonsense-Mediated mRNA Decay.
Ramat Gan, Israel. In Trends Plant Sci, Nov 2015
However, while the loop regulating UPF3 (up-frameshift 3) expression in not vital for mammalian NMD, the sensitivity of UPF3 to NMD is crucial for the overall regulation of plant NMD.
UPF1 P-body localization.
Birmingham, United Kingdom. In Biochem Soc Trans, 2008
However, recent studies have indicated that the core NMD factors UPF1 (up-frameshift-1), UPF2 and UPF3 can associate with P-bodies (processing bodies), which are large cytoplasmic granules replete with proteins involved in general mRNA decay and related processes.