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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

UNC homeobox

Uncx4.1, Uncx
Top mentioned proteins: Pax1, Noggin, Meox1, p300, CAN
Papers on Uncx4.1
Small molecule-directed specification of sclerotome-like chondroprogenitors and induction of a somitic chondrogenesis program from embryonic stem cells.
Nakayama et al., Houston, United States. In Development, 2014
Mesodermal progeny generated using such small molecules were chondrogenic in vitro, and expressed trunk paraxial mesoderm markers such as Tcf15 and Meox1, and somite markers such as Uncx, but failed to express sclerotome markers such as Pax1.
Follistatin interacts with Noggin in the development of the axial skeleton.
Harland et al., In Mech Dev, 2014
Consistent with these observations, expression of the early sclerotome markers Pax1 and Uncx is diminished in Noggin;Follistatin compound mutants.
Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium.
McClintock et al., Lexington, United States. In Mol Cell Neurosci, 2010
UNCX acts downstream of neural determination factors to broadly control transcriptional mechanisms used by neural progenitor cells to specify neural phenotypes
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.
Arnheiter et al., Bethesda, United States. In Dev Biol, 2009
These abnormalities can be traced back to changes in the relative rates of cell proliferation in the rostral and caudal sclerotome compartments, and they are associated with alterations in the expression of at least three transcription factor genes, Tbx18, Uncx, and Bapx1.
Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.
Kusumi et al., Tempe, United States. In Dev Biol, 2009
These include Uncx, a somite gene required for rib and vertebral patterning, and Nrarp, a regulator of Notch/Wnt signaling in zebrafish and a cycling gene in mouse.
Comprehensive survey and classification of homeobox genes in the genome of amphioxus, Branchiostoma floridae.
Holland et al., Tokyo, Japan. In Dev Genes Evol, 2008
We find duplication of several homeobox genes in the cephalochordate lineage (Mnx, Evx, Emx, Vent, Nk1, Nedx, Uncx, Lhx2/9, Hmbox, Pou3, and Irx) and several divergent genes that probably originated by extensive sequence divergence (Hx, Ankx, Lcx, Acut, Atale, Azfh, Ahbx, Muxa, Muxb, Aprd1-6, and Ahnf).
The anuran Bauplan: a review of the adaptive, developmental, and genetic underpinnings of frog and tadpole morphology.
Wassersug et al., Halifax, Canada. In Biol Rev Camb Philos Soc, 2007
Specifically, we hypothesise that: (1) the formation of caudal vertebrae is precluded due to a failure of sclerotomes to form cartilaginous condensations, perhaps resulting from altered expression of a suite of genes, including Pax1, Pax9, Msx1, Uncx-4.1,
Examination of the Lunatic fringe and Uncx4.1 expression by whole-mount in situ hybridization in the embryo of the CKH-Jsr (jumbled spine and ribs) mouse.
Agui et al., Sapporo, Japan. In Jpn J Vet Res, 2005
We examined Lunatic Fringe (Lfng) and Uncx4.1 expression in the presomitic mesoderm (PSM) and somites of Jsr-mutant (CKH-Jsr/+) embryos to elucidate pathogenesis of the Jsr mutation.
Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.
de la Pompa et al., Toronto, Canada. In Curr Biol, 1999
Furthermore, expression of EphA4, mCer 1 and uncx4.1,
Cloning and characterization of four murine homeobox genes.
Nirenberg et al., Bethesda, United States. In Proc Natl Acad Sci U S A, 1996
Four novel murine homeobox genes, Uncx-4.1,
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