Detection of chromosomal breakpoints in patients with developmental delay and speech disorders.
Singapore, Singapore. In Plos One, 2013
Refinement of these regions by Sanger sequencing resulted in the identification of five disrupted genes in three individuals: guanine nucleotide binding protein, q polypeptide (GNAQ), RNA-binding protein, fox-1 homolog (RBFOX3), unc-5 homolog D (C.elegans) (UNC5D), transmembrane protein 47 (TMEM47), and X-linked inhibitor of apoptosis (XIAP).
Netrin-1 simultaneously suppresses corneal inflammation and neovascularization.
Xiamen, China. In Invest Ophthalmol Vis Sci, 2012
METHODS: The expression of netrin-1 and its receptors UNC5A, UNC5B, UNC5C, UNC5D, adenosine 2b receptor (A2BAR), deleted in colorectal cancer (DCC), and neogenin in normal and alkali-burned rat cornea were determined by RT-PCR and/or Western blot analysis, or immunostaining.
Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice.
Milwaukee, United States. In Mol Cancer Res, 2012
Major candidates in these loci are Sema5a, Fmn2, Grem2, Fap, Gsg1l, Xpo6, Rabep2, Eif3c, Unc5d, and Gpr65.