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Secretoglobin, family 3A, member 2

UGRP1, uteroglobin-related protein 1, SCGB3A2
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010] (from NCBI)
Papers on UGRP1
Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation.
Kimura et al., Bethesda, United States. In J Biol Chem, 2011
Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation
The -112G>A polymorphism of the secretoglobin 3A2 (SCGB3A2) gene encoding uteroglobin-related protein 1 (UGRP1) increases risk for the development of Graves' disease in subsets of patients with elevated levels of immunoglobulin E.
Savost'anov et al., Moscow, Russia. In J Appl Genet, 2011
the SCGB3A2 -112G >A polymorphism may be considered as a likely marker linking susceptibility to allergy/asthma and Graves' disease
The cytokine-driven regulation of secretoglobins in normal human upper airway and their expression, particularly that of uteroglobin-related protein 1, in chronic rhinosinusitis.
Liu et al., Wuhan, China. In Respir Res, 2010
Reduced production of UGRP1, which is likely due, at least in part, to a local cytokine environment, may contribute to the hyper-inflammation in chronic rhinosinusitis and correlates with response to surgery.
Variation in Uteroglobin-Related Protein 1 (UGRP1) gene is associated with allergic rhinitis in Singapore Chinese.
Chew et al., Singapore, Singapore. In Bmc Med Genet, 2010
This study documents the association between polymorphisms in UGRP1 and the common cold, suggesting a potential role in its pathogenesis.
Development of a new sensitive ELISA for the determination of uteroglobin-related protein 1, a new potential biomarker.
Bernard et al., Brussels, Belgium. In Biomarkers, 2010
pattern of UGRP-1 concentration resembled that of Clara cell protein, both proteins occurring in high concentrations in amniotic fluid, sputum and BALF and in much lower concentrations in serum and urine
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