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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ubinuclein 1

UBN1, Ubinuclein, VT4
Top mentioned proteins: Histone, Tup1, histamine H1 receptor, HAD, STEP
Papers on UBN1
Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus.
Frigo et al., Houston, United States. In Mol Endocrinol, Oct 2015
Notable was the observation that ubinuclein 1 (UBN1), a key member of a histone H3.3 chaperone complex, was a transcriptional target of the AR/SH3YL1 complex, correlated with aggressive PCa in patients, and was necessary for the maximal androgen-mediated proliferation and migration of PCa cells.
The histone chaperone complex HIR maintains nucleosome occupancy and counterbalances impaired histone deposition in CAF-1 complex mutants.
Probst et al., Clermont-Ferrand, France. In Plant J, Mar 2015
Here, we characterize the role of the plant orthologs Histone Regulator A (HIRA), Ubinuclein (UBN) and Calcineurin Binding protein 1 (CABIN1), which constitute the HIR complex.
Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex.
Marmorstein et al., Philadelphia, United States. In Nat Commun, 2014
The HIRA histone chaperone complex, composed of HIRA, ubinuclein-1 (UBN1) and CABIN1, cooperates with the histone chaperone ASF1a to mediate H3.3-specific binding and chromatin deposition.
Identification of embryonic lethal genes in humans by autozygosity mapping and exome sequencing in consanguineous families.
Alkuraya et al., Riyadh, Saudi Arabia. In Genome Biol, 2014
In addition to revealing mutations in genes previously linked to embryonic lethality in severe cases, our approach revealed seven novel candidate genes (THSD1, PIGC, UBN1, MYOM1, DNAH14, GALNT14, and FZD6).
Improving ovarian tissue cryopreservation for oncologic patients: slow freezing versus vitrification, effect of different procedures and devices.
Pellicer et al., Valencia, Spain. In Fertil Steril, 2014
OBJECTIVE: To compare slow freezing (SF) with four vitrification techniques (VT) for cryopreservation of ovarian tissue (OT) and to evaluate the best protocol for human OT in a xenograft model.
Supratherapeutic vancomycin levels after trauma predict acute kidney injury and mortality.
Salim et al., Los Angeles, United States. In J Surg Res, 2013
Patients were stratified by VT into four groups: VT1 = 0-10 mg/L, VT2 = 10.1-15 mg/L, VT3 = 15.1-20 mg/L, VT4 >20 mg/L.
Placing the HIRA histone chaperone complex in the chromatin landscape.
Adams et al., Glasgow, United Kingdom. In Cell Rep, 2013
The HIRA chaperone complex, comprised of HIRA, UBN1, and CABIN1, collaborates with histone-binding protein ASF1a to incorporate histone variant H3.3 into chromatin in a DNA replication-independent manner.
[A preliminary study of using the expiratory limb of the pressure-volume curve to estimate the dead space in patients suffering from acute respiratory distress syndrome].
Xu et al., Tianjin, China. In Zhonghua Wei Zhong Bing Ji Jiu Yi Xue, 2013
The VT of spirometer (named VT3) and the predetermined VT (VT4) were recorded.
Interaction of Ubinuclein-1, a nuclear and adhesion junction protein, with the 14-3-3 epsilon protein in epithelial cells: implication of the PKA pathway.
Boyer et al., Grenoble, France. In Eur J Cell Biol, 2013
Ubinuclein-1 is a NACos (Nuclear and Adhesion junction Complex components) protein which shuttles between the nucleus and tight junctions, but its function in the latter is not understood.
Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus.
Loppin et al., Villeurbanne, France. In Plos Genet, 2012
Here, we show that Yemanuclein (YEM), the Drosophila member of the Hpc2/Ubinuclein family, is essential for histone deposition in the male pronucleus.
Identification of an ubinuclein 1 region required for stability and function of the human HIRA/UBN1/CABIN1/ASF1a histone H3.3 chaperone complex.
Marmorstein et al., Philadelphia, United States. In Biochemistry, 2012
NHRD domain of UBN1 as being an essential region for HIRA interaction and chromatin organization by the HUCA complex
Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1).
Boyer et al., Grenoble, France. In Exp Cell Res, 2012
a 184-amino acid region (from amino acids 39 to 223) at the N-terminal region of Ubn-1 was responsible for the interaction with the PDZ2 domain of ZO-1
Neural distribution of vasotocin receptor mRNA in two species of songbird.
Maney et al., Atlanta, United States. In Endocrinology, 2011
To identify and map the receptors likely to bind VT and mesotocin, we generated partial cDNA sequences for four VT receptor subtypes, VT1, VT2 (V1b), VT3 (oxytocin-like), and VT4 (V1a), in white-throated sparrow (Zonotrichia albicollis) and zebra finch (Taeniopygia guttata).
Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex.
Adams et al., Bearsden, United Kingdom. In Mol Cell Biol, 2011
Data show that, like HIRA, UBN1, and ASF1a, CABIN1 is involved in heterochromatinization of the genome of senescent human cells.
The nuclear and adherent junction complex component protein ubinuclein negatively regulates the productive cycle of Epstein-Barr virus in epithelial cells.
Manet et al., Lyon, France. In J Virol, 2011
By a chromatin immunoprecipitation (ChIP) assay, the authors show that Ubn-1 blocks EB1-human herpesvirus 4 DNA interaction.
A single mutation results in diploid gamete formation and parthenogenesis in a Drosophila yemanuclein-alpha meiosis I defective mutant.
Aït-Ahmed et al., Montpellier, France. In Bmc Genet, 2009
Yem-alpha is a member of the Ubinuclein/HPC2 family of proteins that have recently been implicated in playing roles in chromatin remodeling in concert with HIRA histone chaperone.
HIRA and Daxx constitute two independent histone H3.3-containing predeposition complexes.
Allis et al., New York City, United States. In Cold Spring Harb Symp Quant Biol, 2009
Here, we show that, before deposition, H3.3 exists in two biochemically distinct complexes, associated with either Daxx or HIRA, Ubinuclein-1, and Cabin-1.
Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.
Adams et al., Philadelphia, United States. In Mol Cell Biol, 2009
Hpc2-related domain of UBN1, UBN2, and Hpc2p is an evolutionarily conserved HIRA/Hir-binding domain, which directly interacts with the N-terminal WD repeats of HIRA/Hir.
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