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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ubiquitin D

Ubiquitin, FAT10, UBD, diubiquitin
human homolog is a diubiquitin protein that may function in antigen processing and presentation [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, V1a, ACID, HAD, Smt3
Papers using Ubiquitin antibodies
Stepwise development of hematopoietic stem cells from embryonic stem cells.
Schmidt Edward E., In PLoS ONE, 2008
... PCR-amplified PRE (EcoRI-NheI), human Ubiquitin C (Ubc) promoter (NheI-XbaI), reverse tet tarnsactivator (rtTA) (XbaI-XhoI) from pTet-on Advanced (CLONTECH) and IRES2 EGFP (XhoI-XhoI) ...
Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Ca(v)2.1 knockin migraine mice.
Cox Gregory A., In PLoS Genetics, 2008
... Eugene, OR, USA); GAPDH (6C5) mouse monoclonal antibody (sc-32233, Santa Cruz Biotechnology Inc., California, USA); Ubiquitin (P4D1), mouse monoclonal antibody (sc-8017, Santa Cruz Biotechnology Inc ...
IRE1 signaling affects cell fate during the unfolded protein response.
Ahmed Niyaz, In PLoS ONE, 2006
... Antibodies to phospho-eIF2α and eIF2α were from Cell Signaling Technology and the IFNAR1 and anti-Ubiquitin antibodies were from Santa Cruz Biotechnology.
Pim kinase substrate identification and specificity
Sapkota Gopal P. et al., In Open Biology, 2006
... Ubiquitin antibody was from Dako (no ...
Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells
Saikumar Pothana et al., In Oncogene, 2005
... Ubiquitin antibody was from Biomol (Plymouth Meeting, PA) and ...
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Papers on Ubiquitin
Effects of inhibition of ubiquitin C-terminal hydrolase L1 (UCH-L1) on sperm incorporation and cortical tension in mouse eggs.
Evans et al., Baltimore, United States. In Mol Reprod Dev, Feb 2016
UNASSIGNED: Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) is thought to have multiple functions in mammalian oocytes and early embryos (e.g., Mtango et al. 2011; Sekiguchi et al. 2006); indeed, UCH-L1 is enriched in the egg cortex (Sekiguchi et al. 2006).
Lipid Geometry and Bilayer Curvature Modulate LC3/GABARAP-Mediated Model Autophagosomal Elongation.
Alonso et al., Bilbao, Spain. In Biophys J, Feb 2016
Ubiquitin-like ATG8 has been related to both membrane expansion and membrane fusion, but the underlying molecular mechanisms are poorly understood.
Antagonistic roles for the ubiquitin ligase Asr1 and the ubiquitin-specific protease Ubp3 in subtelomeric gene silencing.
Tansey et al., Nashville, United States. In Proc Natl Acad Sci U S A, Feb 2016
UNASSIGNED: Ubiquitin, and components of the ubiquitin-proteasome system, feature extensively in the regulation of gene transcription.
Identification of KSHV vIRF1 as a novel interaction partner of human deubiquitinase USP7.
Saridakis et al., Canada. In J Biol Chem, Feb 2016
Ubiquitin Specific Protease 7 (USP7) deubiquitinates p53 and Hdm2 and regulates their stability.
Ubiquitin in the activation and attenuation of innate antiviral immunity.
Dixit et al., Australia. In J Exp Med, Feb 2016
Ubiquitin modifications and cross-talk between proteins within these signaling cascades potentiate IFN-I expression, and inversely, a growing number of viruses are found to weaponize the ubiquitin modification system to suppress IFN-I.
Diabetic Cardiomyopathy: Role of the E3 Ubiquitin Ligase.
Cai et al., Jilin, China. In Am J Physiol Endocrinol Metab, Feb 2016
The E3 ubiquitin ligases (E3s), one component of the ubiquitin-proteasome system, play vital roles in all of the features of DCM listed above.
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
Dixit et al., San Francisco, United States. In Cell, Jan 2016
Here, we show that post-translational regulation of the transcription factors ETV1, ETV4, and ETV5 by the ubiquitin ligase COP1 (also called RFWD2) in β cells is critical for insulin secretion.
In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues.
Morais et al., Leuven, Belgium. In Plos One, Dec 2015
Nonetheless, both Tc and human PINK1 phosphorylate Parkin and Ubiquitin, two physiological substrates of PINK1.
Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment.
Li et al., Atlanta, United States. In Transl Neurodegener, Dec 2015
The identification of mutations in mitochondrial serine/threonine kinase PINK1 or E3 ubiquitin-protein ligase parkin as the cause of autosomal recessive PD opens up new avenues for uncovering neuroprotective pathways and PD pathogenic mechanisms.
Ubiquitin facilitates a quality-control pathway that removes damaged chloroplasts.
Chory et al., Tübingen, Germany. In Science, Nov 2015
A genetic screen identified the plant U-box 4 (PUB4) E3 ubiquitin ligase as being necessary for this process.
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.
Xavier et al., Boston, United States. In Immunity, Nov 2015
CARD9 is a central component of anti-fungal innate immune signaling via C-type lectin receptors, and several immune-related disorders are associated with CARD9 alterations.
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill.
Larsson et al., Erlangen, Germany. In Physiol Rev, Jul 2015
Ubiquitin proteasome and calpain activation trigger muscle proteolysis and atrophy while protein synthesis is impaired.
E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity.
Liu et al., Los Angeles, United States. In Immunity, Jul 2015
Here, we report that the E3 ubiquitin ligase VHL is essential for Treg cell function.
[Research progress on ubiquitin-specific protease in antiviral immunity].
Wei-Lin et al., Hangzhou, China. In Zhejiang Da Xue Xue Bao Yi Xue Ban, Jun 2015
Ubiquitin-specific protease(USP), which belongs to cysteine protease, is an important member of the deubiquitinating enzyme family(DUB).
Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors.
Patrick et al., San Diego, United States. In Front Mol Neurosci, 2014
Changes in synaptic strength underlie the basis of learning and memory and are controlled, in part, by the insertion or removal of AMPA-type glutamate receptors at the postsynaptic membrane of excitatory synapses.
Identification of a novel binding protein of FAT10: eukaryotic translation elongation factor 1A1.
Shao et al., Nanchang, China. In Dig Dis Sci, 2012
This study identified eEF1A1 as a FAT10-specific binding protein, and when the expression of FAT10 was reduced by siRNA knockdown, this resulted in downregulation of eEF1A1 expression in hepatoma cells.
The FAT10- and ubiquitin-dependent degradation machineries exhibit common and distinct requirements for MHC class I antigen presentation.
Kloetzel et al., Berlin, Germany. In Cell Mol Life Sci, 2012
FAT10 modification of the HCMV-derived antigen pp65 (FAT10-pp65) enhances the presentation of the HLA-A2-restricted pp65495-509 antigenic peptide and provide evidence that FAT10- pp65 differs from Ub-modified pp65 in using the proteasome machinery.
Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.
Dick et al., Cambridge, United States. In J Biol Chem, 2012
Data indicate the potential role of cytokine-induced FAT10 expression in regulating Uba6 pathways.
The inherited blindness protein AIPL1 regulates the ubiquitin-like FAT10 pathway.
van der Spuy et al., London, United Kingdom. In Plos One, 2011
implicate FAT10 in retinal cell biology and Leber congenital amaurosis pathogenesis, and reveal a new role of AIPL1 in regulating the FAT10 pathway.
FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis.
Groettrup et al., Konstanz, Germany. In Nat Commun, 2011
findings show how FAT10 and NUB1L dock with the 26S proteasome to initiate proteolysis; identified the 26S proteasome subunit hRpn10/S5a as the receptor for FAT10, whereas NUB1L can bind to both Rpn10 and Rpn1/S2.
More papers using Ubiquitin antibodies
Neuronal ubiquitin and neurofilament expression in different lysosomal storage disorders
Elleder Milan et al., In Acta Neuropathologica, 1991
... Ubiquitin (rabbit polyclonal)DAKO, Copenhagen, Denmark ...
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